Titlebook: Anticancer Plants: Mechanisms and Molecular Interactions; Volume 4 Mohd Sayeed Akhtar,Mallappa Kumara Swamy Book 2018 Springer Nature Singa

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Omics: A Holistic Approach in Cancer Treatment,hemicals like camptothecin derivatives, vinblastine, vincristine, withanolides, withaferin A, topotecan, irinotecan, etoposide, and paclitaxel (taxol) are part of the armamentarium to treat cancer. Various approaches can be used in studying molecular markers to distinguish subtypes of disease and pr

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Plant miRNAs and Phytomolecules As Anticancer Therapeutics,components, i.e., plant microRNA, has been overlooked since years and may prove to play a major role as a therapeutic molecule. MicroRNAs are attributed to control gene expression at a very fine level both transcriptionally and posttranscriptionally. Studies have indicated that aberrant expression o

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CADD Studies Applied to Secondary Metabolites in the Anticancer Drug Research,puter-aided drug design) studies are increasingly being used in both industries and universities. They involve an understanding of the molecular interactions from both qualitative and quantitative points of view. These methods generate and manipulate three-dimensional (3D) molecular structures, calc

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Anticancerous Plant Compounds Affecting the Power House of Cancerous Cells: A Possible Herbal Mitoc signaling pathways inside cancer cells. This emerging class of drugs is called as mitocans that affect the activities related to mitochondria, such as hexokinase inhibition, electron transport/respiratory chain blockage, activation of the mitochondrial membrane permeability transition pore targetin

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Phytoestrogens as a Natural Source for the Possible Colon Cancer Treatment,rase activities and also by suppressing the process of angiogenesis. Findings from molecular, cellular, and animal studies suggest that PE may potentially confer health benefits related to colon cancer (CC) pathology. High incidence of CC might be resulted with the intake of high-calorie diet includ

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Bioinformatics Approaches for Genomics and Post Genomics Applications of Anticancer Plants, new plants with anticancer potential. Also, certain agents that have failed in earlier clinical studies are considered for evaluation to obtain novel anticancer drugs using bioinformatics approaches and this field has triggered more interest among researchers in recent years. The aim of this chapte