Titlebook: Antibody Engineering; Roland Kontermann,Stefan Dübel Book 20011st edition Springer-Verlag Berlin Heidelberg 2001 Amino acid.Antigen.Cell p

headlong

Proximity (ProxiMol) and Step-Back Selectionsnically complex and this results in difficulties in specifically selecting antibodies which bind to a given cell surface molecule without selecting for a host of unwanted specificities in parallel. The desired antigen specificity can in many cases be obtained, but only after an intensive screening p

違抗

全能

Selection of Human Antibody Fragments by Anti-Idiotypic Interaction compared to the background phages or the antigen is not available in a suitable form, resulting in nonspecific adherence of the phages. For this reason researchers used anti-idiotypic antibodies for the panning procedure. These were generated by immunization of rabbits with human IgG Fab (idiotype)

SPASM

金桌活畫(huà)面

objection

erythema

Recombinant Antibodiesle, an immense number of different molecules, bearing different specificities, is required. This diversity is generated by somatic recombination and hypermutagenesis of a set of variant genes. The genetic information for this repertoire of different antibodies is stored in the B-cell pool of our lymphatic system.

extinct

平淡而無(wú)味

遺產(chǎn)

https://doi.org/10.1007/978-3-662-04605-0Amino acid; Antigen; Cell preparation; Expression; Immunologie; Polymerasekettenreaktion; Zellpreparatione