Titlebook: Antibiotic Resistance Methods and Protocols; Stephen H. Gillespie Book 20011st edition The Editor(s) (if applicable) and The Author(s), un

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Stephen H. GillespieIncludes supplementary material:

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The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

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https://doi.org/10.1007/3-7908-1666-3The first appearance of clinically significant penicillin-resistant . (pneumococcus) occurred in 1967 in Australia (.) and penicillin resistant and multiresistant pneumococci have subsequently spread globally and reached high prevalence in many countries (.).

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Drug Susceptibility of ,Through the Mycolic Acid IndexThe methods accepted to determine antimicrobial drug susceptibility of mycobacteria are based on the determination of the microorganisms’ growth on solid or liquid medium containing a specified concentration of a single drug.

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Rapid Rifamycin Susceptibility Testing of Small-Volume , Cultures by Detection of Precursor rRNAClinical laboratory identification of . and the . complex (MAC) has been facilitated in recent years by new DNA and RNA amplification tests (.-.). However, drug susceptibility testing of slowly-growing mycobacteria remains time-consuming and costly, and the need for more rapid tests remains acute (.).

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Detection of Penicillin Resistance in , by a Seminested PCR StrategyThe first appearance of clinically significant penicillin-resistant . (pneumococcus) occurred in 1967 in Australia (.) and penicillin resistant and multiresistant pneumococci have subsequently spread globally and reached high prevalence in many countries (.).