Titlebook: Antibiofilm Strategies; Current and Future A Katharina Richter,Kasper N?rskov Kragh Book 2022 The Editor(s) (if applicable) and The Author(

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Springer Series on Biofilmshttp://image.papertrans.cn/a/image/158399.jpg

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Antibiotic Resistance Development in Bacterial Biofilmss. This mode of growth is characteristically associated with chronic infections, marked by the persistence of the bacteria regardless of proper antimicrobial therapies. Biofilms are up to 100–1000 times more resistant to antibiotics than planktonic cells. The basis for resistance to antimicrobials i

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Clinical Translation of Biofilm Dispersal Agentsdeveloping new agents that address chronic infection is arduous. As biofilms are a major strategy used by microbes to evade the immune response and antibiotics, developing therapeutics that prevent or destroy biofilms has become a major focus for many researchers. One promising anti-biofilm strategy

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Chemical Regulation of , Biofilm Formation as a Potential Treatment for Persistent Infectionsesearch in biofilms, revealing that the biofilm life form is an essential factor for bacteria to develop persistent infections, which is because of an increased resistance to the immune system and conventional antibiotics. However, the increased scientific focus on studying the underlying mechanisms

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Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections re-sensitizing infectious biofilms to antibiotics by supplemental O. has recently been explained by the pathophysiological conditions of the infectious microenvironment. In this chapter, we argue that multifactorial restrictions of O., caused by O. depletion within the infectious microenvironment,