Titlebook: Antibacterials; Volume I Jed F. Fisher,Shahriar Mobashery,Marvin J. Miller Book 2018 Springer International Publishing AG, part of Springer

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1862-2461 teractions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known978-3-030-09821-6978-3-319-68097-2Series ISSN 1862-2461 Series E-ISSN 1862-247X

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The Antibiotic Future,tly grapple with the key scientific challenges that prevent forward motion. The future fate of antibiotic discovery will depend upon the degree to which the rate limiting steps of discovery are fully recognized, and the discovery technology turns to overcoming these blockades.

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Synergistic Antibiotic Combinations,lly with no clinical data to support their use. Because combination therapy will continue to be used in the absence of supportive clinical data, it will be important in the future to investigate mechanistic principles that may lead to predictive models for successful patient outcomes.

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Topics in Medicinal Chemistryhttp://image.papertrans.cn/a/image/158395.jpg

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https://doi.org/10.1007/978-3-642-49191-7cterial pathogens, referred to here as antibiotics? What role will these small-molecule antibiotics have in the control of the bacterial infections of the future? Although there is today increased activity in the field of new antibiotic discovery, the history of this field over the past 30?years is

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