Titlebook: Anti-Idiotypic Vaccines; P.-A. Cazenave Book 1991 Springer-Verlag New York Inc. 1991 Antigen.cell.genes.parasite.parasites.research.vaccin

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0941-875X pic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the978-1-4612-7750-7978-1-4612-2992-6Series ISSN 0941-875X

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Anti-Idiotypic Antibodies as Potential Viral Vaccines,ve led to the development of a new generation of vaccines. Recombinant proteins, synthetic peptides, and anti-idiotypic antibodies represent relatively new technologies that are currently being examined for their potential use in stimulating immunity against various microorganisms (reviewed in 3 and

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Small Human VH Gene Families Show Remarkably Little Polymorphism,geneity in that no two sequences were more than 85% identical. As murine proteins were sequenced in the late 1960s and early 1970s, more homogeneous structures were seen, and, as an understanding of the V, D, and J gene segments became apparent, it was obvious that, although rare, occasionally two i

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Anti-Idiotypic Vaccines for Carbohydrate Antigens,o a carbohydrate determinant, whether a polysaccharide or an oligosaccharide side chain of a glycoprotein or a synthetic conjugate. In each case the subject will be discussed in terms of the ability of anti-idiotypes to stimulate a response and in terms of the data presented that suggest that the an

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Anti-Idiotypic Tumor Vaccines,stimulation of the lymphocyte clones, which have the potential to mount a response to tumor-associated antigens (TAAs) (1) or due to suppression of cytotoxic T lymphocyte activity by progressive tumor growth (2). A common explanation for the absence of antitumor immunity is that the immune system ha

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,Utilization of Anti-Idiotypic Antibodies as Molecular Probes of Virus—Receptor Interaction,athology. We will describe our work in two different viral systems. First we review our studies of the reovirus type 3 system. We have utilized the reovirus type 3—cellular receptor interaction as a model system to develop such a strategy. We demonstrate the utility of monoclonal anti-idiotypic (ant