Titlebook: Antenatal Diagnosis of Fetal Abnormalities; James O. Drife (Professor of Obstetrics and Gynaec Book 1991 Springer-Verlag London Limited 19

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The Northern Regional Fetal Abnormality Surveyng programme is first set up, but the only available information on the accuracy of sonar diagnosis was coming from a small number of referral centres with a concentration of specialist experience serving an ill-defined catchment area.

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Book 1991, detailed ultrasound scanning and cordocentesis are being evaluated by obstetricians, and refinement of biochemical testing is widening the scope of maternal serum screening. In the laboratory, dramatic advances in molecular biology are occurring: families at risk of genetic disease can be investig

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James O. Drife (Professor of Obstetrics and Gynaec

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Herwart Opitz,Wilfried K?nig,Manfred Schütterkers on ultrasound scan [1] very important. Although secondary prevention is all that is possible at present for mutant chromosomal disorders, attention must be focused on the need to understand those factors which cause constitutional chromosomal abnormalities to occur, so that primary prevention

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Book 1991fits and limitations of prenatal diagnosis. Obstetricians, scientists and health service managers will face the difficult task of deciding how prenatal diagnosis can be made available to women in a caring and cost-effective way. Recognising the rapid progress in this field, the Royal College of Obst

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t the benefits and limitations of prenatal diagnosis. Obstetricians, scientists and health service managers will face the difficult task of deciding how prenatal diagnosis can be made available to women in a caring and cost-effective way. Recognising the rapid progress in this field, the Royal College of Obst978-1-4471-1856-5978-1-4471-1854-1

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Fetal Karyotyping Using Chorionic Villus Samplesrkers on ultrasound scan [1] very important. Although secondary prevention is all that is possible at present for mutant chromosomal disorders, attention must be focused on the need to understand those factors which cause constitutional chromosomal abnormalities to occur, so that primary prevention

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Trends in Prevalence of Congenital Abnormalitiesses, better obstetric care and the improvement in social and environmental conditions. Congenital abnormalities, with a few exceptions, have not shared this amelioration. In 1978, the Medical Research Council, London, in a review of clinical genetics, emphasised that “handicaps due to a genetic diso