Titlebook: Animal models in cardiovascular research; David R. Gross Book 19942nd edition Springer Science+Business Media Dordrecht 1994 anesthesia.at

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Cardiovascular effects of other drugs commonly used in cardiovascular research,nvestigators to minimize these effects. This has been done by reducing dosages, increasing the use of narcotic analgesics, whose deleterious cardiovascular effects are less than those of the general anesthetics, and by the use of neurolept analgesia regimens. Under these circumstances, voluntary and

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General anesthesia,eviewed data obtained from microelectrode studies of single cardiac cells, isolated hearts and intact animals. Pentobarbital, injected into the sinus node artery produces a dose-dependent negative chronotropy, SA nodal block and AV nodal rhythms, at high doses. Barbiturates, in general, prolong AV j

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