Titlebook: Animal Models of Depression; George F. Koob,Cindy L. Ehlers,David J. Kupfer (Pr Book 1989 Birkh?user Boston 1989 behavior.biology.central

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Electrophysiology of the Locus Coeruleus: Implications for Stress-Induced Depressionn. This procedure represents the most widely studied animal model of psychopathology. As a result of this extensive study, similarity of the model to human depression has been shown with respect to etiology, symptomatology, and responsiveness to treatment. These similarities will now be reviewed briefly.

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Anhedonia as an Animal Model of Depressiontoms of a major depressive episode is a failure to obtain pleasure from activities that previously brought enjoyment (Klein, 1974). Recreational activities, sex, and eating now provide little or no gratification. The mood of the individual is characterized as depressed, sad, hopeless, and discouraged.

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Pharmacological Probes in Primate Social Behaviore in major psychiatric categories. Therefore, animal models of these disorders which include evaluation of social behavior add an important dimension to the model. Non-human primates have been used as subjects in most social studies because of their well documented social structure and noted behavioral similarities to humans.

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Basis of Development of Animal Models in Psychiatry: An Overviews expanded enormously. There are many approaches to developing animal models of depression in particular, and it will quickly become apparent that there is quite a variety of studies underway. In order to understand and evaluate the rapidly expanding literature in several areas of animal modeling re

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Animal Models: Promises and Problems the etiology of the illness but to effect a cure. The problem is that it is not easy to develop a true model of a mental illness. It could be that animal models are not possible because mental illnesses may be uniquely human disorders.

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