| 期刊全稱 | Animal Models of Dementia | | 影響因子2023 | Peter Paul De Deyn,Debby Van Dam | | 視頻video | http://file.papertrans.cn/158/157635/157635.mp4 | | 發(fā)行地址 | Appeals to a broad readership from neuropathologists, pharmacists, biochemists, and biologists to clinical neurologists.Features a large, comprehensive section on Alzheimer’s disease.Includes contribu | | 學(xué)科分類 | Neuromethods | | 圖書封面 |  | | 影響因子 | With an ever-increasing elderly population and the resultant rising levels of dementia-related disorders, preclinical research based on animal models is pivotal to our knowledge of underlying molecular mechanisms and drug discovery aiming at the development of therapeutic strategies alleviating or preventing the neurological devastation.In Animal Models of Dementia, expert researchers provide contributions that stress the importance of extensively validated animal models in drug discovery and development in order to predict clinical activity.Beginning with general aspects of animal modeling, related ethical issues, and essential methodological considerations, the highly detailed volume then continues with various levels of model validation, including pathological, behavioral, neurochemical, pharmacological, and imaging aspects, followed by sections focused on specific disorders, such as Alzheimer’s disease, Parkinson’s disease, metachromatic leukodystrophy and adrenoleukodystrophy, amyotrophic lateral sclerosis, frontotemporal dementia as well as vascular dementia and more.As a volume in the renowned Neuromethods series, this book offers a detailed, yet accessible, overview of curr | | Pindex | Book 2011 |
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