Titlebook: Animal Models of Behavior Genetics; Jonathan C. Gewirtz,Yong-Kyu Kim Book 2016 Springer Science+Business Media New York 2016 animal models

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A , Model for Aggressiony genes, environment, and interaction between genes and environment. The fruit fly . model system offers the advantage of having powerful genetic tools that can be used to unravel the roles of genes and other factors in behavior. In this chapter, studies of aggressive behavior in . will be reviewed

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The Genetics of Impulsivity: A Synthesis of Findings in Humans and Rodent Modelsogical disorders such as pathological gambling, drug addiction, attention deficit hyperactivity disorder, and Parkinson’s disease. Given the central role of impulsivity in these and other brain disorders there has been widespread interest in elucidating the neurobiological mechanisms and particularl

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The Neurobiology and Genetics of Affiliation and Social Bonding in Animal Models. Although very little is known regarding the underlying neurobiological mechanisms influencing the development of human relationships, studies using animal models have gained insights into the regulation of this process in other species. In this chapter we will discuss several animal models that ha

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Genetic Models of Alzheimer’s Disease: The Influence of Apolipoprotein E allele Isoforms on Behaviou, presenilin 1, presenilin 2 and the apolipoprotein E (APOE) genes. We focus here on the behavioural impact in laboratory animals of polymorphisms in the APOE gene. In humans, this gene presents in the form of three allele variants (ε2, ε3 and ε4), with the ε4 polymorphism conferring a significantly

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Social Endophenotypes in Mouse Models of Psychiatric Diseasespectrum disorders (ASDs) and schizophrenia, are impairments in socio-communicative behavior. These impairments have been proposed as candidate endophenotypes of disease processes, being present in prodromal and active stages of disease, as well as in undiagnosed relatives. The genetic bases for the

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Animal Models of Addiction: Genetic Influencesrstanding of the role genes play in the vulnerability to such compulsive behaviors. Rodent models, in particular, have shown that traits such as impulsivity and high sweet consumption, among others, are under strong genetic influence and positively associated with drug intake, similar to human popul