Titlebook: Animal Models in Psychopharmacology; B. Olivier,J. Mos,J. L. Slangen Book 1991 Springer Basel AG 1991 pharmacology.psychopharmacology.rese

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Optimum Population: An Introductionair” model of depression is available for primates, neuroscience work would be facilitated by a simplified model that could be used routinely. In the following work we analyzed the ability of social isolation to facilitate immobility in the mouse forced swimming test and to decrease separation induc

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Animal Models and Recent Developments in the Search for Novel Anxiolyticse development and validation of animal models. It has been proposed that anxiolytic activity may be shown by compounds acting at serotonin receptors (5HT., 5HT., 5HT.) and at excitatory amino acid receptors, as well as by ω (BZ) receptor ligands which differ structurally from benzodiazepines. The be

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Rat Pup Ultrasonic Vocalizations: An Ethologically Relevant Behaviour Responsive to Anxiolytics by several different classes of anxiogenics. In addition to detecting anxiolytic efficacy, this behaviour may be a useful tool for studying selective aspects of the neurobiology of anxiety. It should be noted however that pharmacologic results with rat pup studies depend on both the ontogeny of the

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