Titlebook: Animal Cell Technology: Basic & Applied Aspects; Proceedings of the F Kazumi Yagasaki,Yutaka Miura,Yoshihiro Nomura Conference proceedings

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Optimization of the Production of Retroviral Vectors ./genmed). Despite of their limitations (i.e. relatively low titer and activity, use limited to dividing cells), MLV vectors lead to permanent gene transfer and expression and the first clinical success of gene therapy has been obtained using this technology (Cavazzana-Calvo et al. 2000).

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https://doi.org/10.1007/978-1-4419-0699-1at involve the WW domain have been implicated in human diseases including Muscular Dystrophy (MD) and Alzheimer’s Disease (AD) [4]. Recently, the WW domain was mapped in the human proteome and more than 69 000 interactions mediated by 70 WW domains were uncovered and characterized [5].

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