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Titlebook: Analysis of Psychiatric Drugs; Alan A. Boulton,Glen B. Baker,Ronald T. Coutts Book 1988 Springer Science+Business Media New York 1988

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期刊全稱Analysis of Psychiatric Drugs
影響因子2023Alan A. Boulton,Glen B. Baker,Ronald T. Coutts
視頻videohttp://file.papertrans.cn/157/156424/156424.mp4
學(xué)科分類Neuromethods
圖書封面Titlebook: Analysis of Psychiatric Drugs;  Alan A. Boulton,Glen B. Baker,Ronald T. Coutts Book 1988 Springer Science+Business Media New York 1988
影響因子In this volume, we hope to cover the malor techniques that are presently being used to analyze the actions of drugs used in psyc- atry. The contributors of the chapters are active researchers who have considerable practical experience with the techniques they are describing, and the emphasis in the chapters is on three types of psychiatric drugs, namely antidepressants, antipsychotics, and anxiolytics. The first chapter, by Curry and Yu, discusses protein binding of psychotropic drugs, with special reference to equilibrium ana- sis as the method of assessment and to lipophilicity correlations. Since many of the drugs used in treating psychiatric disorders are bound extensively to protein, this aspect is of great importance with regard to their therapeutic actions and toxicity, Basic mat- matical models, techniques for the study of protein binding, molecular aspects of protein binding, binding in relation to lipophilicity, indirect approaches to measurement of the fraction of drug bound, the function of protein binding, and tissue binding are among the topics discussed. Chapter 2, by Norman and B- rows, deals with the principles of isotope derivative assays and their applications to
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Use of Direct Democracy in the Jura Conflictic symptoms. The first goal, i.e., identifying drugs that may be clinically useful, and the second goal, i.e., analyzing the mechanisms of action of psychotherapeutic drugs with animal behavior, are in fact intertwined. This chapter is written from a pragmatic viewpoint utilizing currently acceptabl
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Lars P. Feld,Gebhard Kirchg?ssnernts have been used extensively. Foremost among these is [.H]-imipramine, a tricyclic antidepressant that inhibits neuronal serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (noradrenaline, NA) transport. Other radiolabeled antidepressants whose high-affinity binding sites have been studied in
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,Gas Chromatographic— Mass Spectrometric Analysis of Antidepressants, Neuroleptics, and Benzodiazepi drugs and their relevant metabolites. These properties make MS the method of choice for the analysis of these compounds. Disadvantages of this technique, however, include the initial high cost of equipment, the sophisticated level of skill required for the operation and maintenance of the instrumen
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High-Performance Liquid Chromatographic Analysis of Antidepressants, Neuroleptics, and Benzodiazepi storage, and handling and specimen preparation prior to chromatography will be addressed. Detailed evaluations of individual methods will not be done, and the appropriate articles should be searched for more specific information.
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High-Affinity Binding of Antidepressants to Platelets and Brain Tissues,nts have been used extensively. Foremost among these is [.H]-imipramine, a tricyclic antidepressant that inhibits neuronal serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (noradrenaline, NA) transport. Other radiolabeled antidepressants whose high-affinity binding sites have been studied in
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