Titlebook: Anal Cancer; A Comprehensive Guid Jeffrey Meyer,Lisa Kachnic Book 2019 Springer Nature Switzerland AG 2019 anal cancer.lower gastrointestin

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Die unvermeidliche Universalgeschichteversimplified, but the alternative perspectives on this anatomic region and its histologic characteristics influence how anal cancer pathology is conceptualized and ultimately treated. In this chapter, we highlight the divergent definitions and complexity of anal canal anatomy, review the anatomic a

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https://doi.org/10.1007/978-3-0348-6749-8tting prior to abdominoperineal resection by Norman Nigro and colleagues at Wayne State University Hospital. Chemoradiotherapy with 5-fluorouracil, mitomycin C, and radiation therapy yielded complete pathologic responses obviating the need for surgery upfront. Attempts have been made to eliminate or

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https://doi.org/10.1007/978-3-0348-6749-8to be highly effective in this disease; however, it is associated with acute and late toxicities. Toxicities associated with the standard chemotherapy agents (5-fluorouracil [5-FU] and mitomycin C) include diarrhea, nausea, stomatitis, mucositis, hand-foot syndrome, and myelosuppression. Acute toxic

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https://doi.org/10.1007/978-3-658-42608-8ents experience local relapse, and salvage surgery is a second line of treatment for these patients. Wide local excision, abdominoperineal resection, pelvic exenteration with or without sacrectomy, and inguinal node dissection are all surgical options. In this chapter, we review the management and t

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,Klinik der Harnabflu?st?rungen,re rare and frequently misdiagnosed. Those covered in this chapter include Paget’s disease, basal cell cancer, and rhabdomyosarcoma in the pediatric population. Workup of these perianal lesions is similar, consisting of histologic tissue diagnosis followed by clinical and radiographic staging evalua

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