Titlebook: Amino Acid Availability and Brain Function in Health and Disease; Gerald Huether Conference proceedings 1988 Springer-Verlag Berlin Heidel

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The Importance of the Liver as a Regulator of Amino Acid Supply to the Brainn the liver. The concentrations of the amino acids in the blood are regulated by the rates of dietary intake, protein turnover and peripheral metabolism (occurring mostly in the liver; see Figure 1). The aromatic amino acids are of particular interest because of their role as precursors of several n

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Bioavailability of Amino Acids and Amino Acid Precursors for Neurotransmitter Action: The Role of Hotate), precursors of neurotransmitters (tyrosine and tryptophan), and transducers of transmitter components (glycine and serine in transmethylation processes). These amino acids derive exogenously from nutrients, and endogenously from the intermediary metabolism, and from the degradation of protein

吼叫

Feeding, Stress, Exercise and the Supply of Amino Acids to the Brainursors of transmitter amines. In the past, most attention has been paid to two of these, tyrosine and tryptophan, which through the action of tyrosine hydroxylase and tryptophan hydroxylase respectively are converted to 3,4-dihydroxyphenylalanine (dopa) and 5-hydroxytryptophan by reactions which are

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Enzymes of the Cerebrovascular Endothelium; Possible Relevance to the Interpretation of Precursor-Loto restrict solute entry into the brain, but more generally as a regulatory system consisting of transport processes, enzymatic mechanisms and a receptive surface to neurotransmitters (NTs) and neurohormones which limits the actions of blood-borne substances on brain function. However, BBB function

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Effects of Tryptophan Administration on the Synthesis, Storage and Metabolism of Serotonin in the Hy. The initial and rate-limiting step in the synthesis of 5HT is the conversion of L-tryptophan to 5-hydroxytryptophan (5HTP), a reaction catalyzed by tryptophan hydroxylase. Newly formed 5HTP is rapidly decarboxylated by aromatic L-amino acid decarboxylase to 5HT which is either stored in vesicles f