Titlebook: Amine Oxidases: Function and Dysfunction; Proceedings of the 5 K. F. Tipton,M. B. H. Youdim,G. A. Lyles Conference proceedings 1994 Springe

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https://doi.org/10.1007/978-3-7091-7742-6decrease in MAO-B in the older animals. These results show marked species differences in the distribution and age-related changes of MAO and might help to elucidate the high sensitivity of B1/C57 mouse of MPTP, which increases with age.

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Die Entstehungsgeschichte des Problems,in the mouse heart. Heart MAO-B activity was found to significantly increase (about 70%) with age in both male and female mice, whereas MAO-A activity remained unchanged. Compared to age-matched rats, serotonin-deaminating activity was about 35 times and 204 times lower in young and old mice, respectively.

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Species differences in changes of heart monoamine oxidase activities with agein the mouse heart. Heart MAO-B activity was found to significantly increase (about 70%) with age in both male and female mice, whereas MAO-A activity remained unchanged. Compared to age-matched rats, serotonin-deaminating activity was about 35 times and 204 times lower in young and old mice, respectively.

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