Titlebook: Alzheimer: 100 Years and Beyond; Mathias Jucker,Konrad Beyreuther,Yves Christen Book 2006 Springer-Verlag Berlin Heidelberg 2006 Alzheimer

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0945-6066 ection comprised mainly of articles by the invited speakers and also of a few other prominent researchers, is meant to be a record of those events..978-3-642-07232-1978-3-540-37652-1Series ISSN 0945-6066 Series E-ISSN 2196-310X

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https://doi.org/10.1007/978-3-642-90801-9est. In the search for improved symptomatic and possibly neuroprotective treatments, acetylcholine may have an unexpected role. The observation that M1 and M3 receptor stimulation with cholinergic drugs drives APP processing into the α-secretase pathway adds a modern coda to the acetylcholine-AD story that is still unfinished.

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Acetylcholine in AD: Expectations meet realityest. In the search for improved symptomatic and possibly neuroprotective treatments, acetylcholine may have an unexpected role. The observation that M1 and M3 receptor stimulation with cholinergic drugs drives APP processing into the α-secretase pathway adds a modern coda to the acetylcholine-AD story that is still unfinished.

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A chapter in the development on Alzheimer’s disease researchedge on the disease was accumulated since the 1970s. The dramatic research advances during the last three decades propelled the disease from near obscurity to the forefront of modern biomedical science. The remarkable transformation of this field of study is reflected by the exponential increase in

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Presenile forms of Alzheimer’s disease in 2006 to be characterized by the early onset of important disturbances of instrumental functions. Moreover, atypical presentations, which are characterized by the progressive disruption of one instrumental function (visual or linguistic), appear to be more frequent in younger subjects. This pattern is li

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