Titlebook: Alternatives to Animal Testing; Proceedings of Asian Hajime Kojima,Troy Seidle,Horst Spielmann Conference proceedings‘‘‘‘‘‘‘‘ 2019 The Edit

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Conference proceedings‘‘‘‘‘‘‘‘ 2019educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of .Alternatives to Animal Testing. is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0..

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Testing Method Development and Validation for , Skin Irritation Testing (SIT) by Using Reconstructeend has been changed from . to . testing due to 3R (replacement, reduction, refinement) requirements has resulted from a recent animal testing ban in Taiwan. RhE (Reconstructed human Epidermis) models use normal human keratinocytes to form a multi-layered epidermis including a stratum corneum at the

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Guidance on the Use of Alternative Test Methods for the Safety Assessment of Cosmetics and Quasi-drlternative Methods (JaCVAM) has accelerated applications for new test methods developed as alternatives to animal testing for the safety assessment of the manufacture and sales of cosmetic products and quasi-drug products that contain new ingredients. Taking advantage of this opportunity to strongly

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