Titlebook: Allergy and Allergic Diseases; The New Mechanisms a Judah A. Denburg Book 1998 Springer Science+Business Media New York 1998 Immunity.infla

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Human Langerhans Cellskin-associated lymphoid tissue (SALT) . or skin immune system (SIS) . contains all elements required for recognition and efficient immune response against foreign structures invading this interface epithelium, which is in close contact with the environment. In this first line of immunosurveillance i

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Role of Basophils in Allergic Reactionsmine in their granules and express high-affinity immunoglobulin E (IgE) binding sites .,.. In addition, blood basophils can release their mediators in response to an allergen or other stimuli. In patients with allergic asthma, rhinitis, or contact dermatitis, basophils can be detected at the sites o

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The Role of the Bone Marrow in Allergic Diseasetically summarized in Fig. 1. The development of airway inflammation occurs in response to the multiple actions of mediators released primarily from mast cells and T-helper 2 (Th2) cells, including autocrine upregulation and recruitment of inflammatory cells via target cell priming, adhesion molecul

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Neurogenic Inflammation in Allergic Diseasees to cause symptoms, such as cough and chest tightness, sneezing, and itching, which are among the most troublesome aspects of allergic diseases. Sensory nerves themselves may also release neurotransmitters that increase inflammation, and this is termed neurogenic inflammation. The phenomenon of ne

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