Titlebook: Algorithms and Methods in Structural Bioinformatics; Nurit Haspel,Filip Jagodzinski,Kevin Molloy Book 2022 The Editor(s) (if applicable) a

DOTE

Explaining Small Molecule Binding Specificity with Volumetric Representations of Protein Binding Siplanations about mechanisms for achieving specificity. As a result, mechanistic explanations can potentially be extended to a large space of mutations, including the identification of those that may alter overall binding preferences.

ATP861

Machine Learning-Based Approaches for Protein Conformational Exploration,omings, and their improved variants. We then focus on new machine learning-based strategies that have been a research hot spot for computational biologists in recent years. These strategies either suggest new approaches or enhancements of existing ones.

ENACT

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Frank J. Robertz,Ruben Wickenh?userions have a stronger correlation with functional changes in the respective proteins compared to the other kinds of mutations. In this review article, we overview various aspects of InDels, including their origin, their detection among protein sequences, and various methods of analyzing their effects.

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Detection and Analysis of Amino Acid Insertions and Deletions,ions have a stronger correlation with functional changes in the respective proteins compared to the other kinds of mutations. In this review article, we overview various aspects of InDels, including their origin, their detection among protein sequences, and various methods of analyzing their effects.

Osteoporosis

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Algorithms and Methods in Structural Bioinformatics978-3-031-05914-8Series ISSN 1568-2684 Series E-ISSN 2662-2432

匯總

Angiogenesis

Frank J. Robertz,Ruben Wickenh?userprotein that performs vital functions. Hence, investigating and interpreting protein dynamics as well as their structures can provide us with invaluable insights regarding how proteins perform their functions. In this chapter we survey both experimental and . methods used to study protein dynamics a

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Frank J. Robertz,Ruben Wickenh?usery of debilitating diseases. Performing point mutations via mutagenesis experiments on physical proteins to infer the effects of the mutations is time consuming even for a single amino acid substitution, let alone for all possible mutations. Computational approaches are available for generating mutan