Titlebook: Aldehyde Dehydrogenases; From Alcohol Metabol Jun Ren,Yingmei Zhang,Junbo Ge Book 2019 Springer Nature Singapore Pte Ltd. 2019 Aldehyde deh

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https://doi.org/10.1007/978-94-017-1209-5st Asians and is a significant risk factor for both coronary spasm and AMI through accumulation of toxic aldehydes, thereby contributing to oxidative stress, endothelial damage, vasoconstriction, and thrombosis. Toxic aldehydes are thus identified as risk factors to be targeted for the treatment of coronary spasm and AMI.

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Association of East Asian Variant Aldehyde Dehydrogenase 2 Genotype (,2*2*) with Coronary Spasm andst Asians and is a significant risk factor for both coronary spasm and AMI through accumulation of toxic aldehydes, thereby contributing to oxidative stress, endothelial damage, vasoconstriction, and thrombosis. Toxic aldehydes are thus identified as risk factors to be targeted for the treatment of coronary spasm and AMI.

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Aldehyde Dehydrogenase (ALDH) 2 in Diabetic Heart Diseases,g cardiac function. This chapter assesses the role of ALDH2 in diabetic heart diseases by examining preclinical studies where ALDH2 activity is perturbed in both decreased and increased directions. In doing so, issues in improving ALDH2 activity in select human populations are elucidated, and further research directions are discussed.

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ALDH2 Polymorphism and Ethanol Consumption: A Genetic-Environmental Interaction in Carcinogenesis, when ALDH2 mutation combined with heavy alcohol consumption, suggesting a genetic-environmental interaction in carcinogenesis. This may provide us with a potential target for cancer prevention and treatment.

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Book 2019ese processes. It thoroughly reviews the roles of ALDH family in alcohol metabolism, as well as recent findings of their emerging roles in a variety of human pathologies such as cardiovascular diseases, diabetes, obesity, stroke, cancer, liver diseases and kidney diseases. Delicate contribution of A

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Aldehyde Dehydrogenases Genetic Polymorphism and Obesity: From Genomics to Behavior and Health,nsumption behavior in physiological mechanism studies, we proposed a model by which the physiological and behavioral consequences of alcohol consumption serve as an intermediary process between polymorphisms in . and obesity.