Titlebook: Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction; David Raeburn (Department Head),Mark A. Giembycz ( Book 19

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David Raeburn (Department Head),Mark A. Giembycz (

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Vorbereitung des Trainings und Nachbetreuungthesis and release of . and related kinins such as kallidin (Lys-BK, KD) have been reviewed [1–4], and will not be detailed further at present. . exerts numerous effects, via cell-surface receptors, on virtually every mammalian organ, tissue and cell type [4–7]. In addition, kinins have been implica

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https://doi.org/10.1007/978-3-662-68783-3ting lung function and activating reflex bronchoconstriction and cough. In this context, capsaicin, the natural pungent ingredient of red peppers, has been extensively used by respiratory physiologists as a chemical probe to activate reflexes arising from the airways.

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https://doi.org/10.1007/978-3-662-68783-3it was identified in the central and peripheral nervous systems [3], and has since been recognized as a neuropeptide with wide distribution, acting as a neuroransmitter or neuromodulator in the lung and practically all other organs and tissues. The discovery and characterization of VIP has spawned a

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https://doi.org/10.1007/978-3-662-68783-3. It is now known that this extract contained a peptide, atrial natriuretic peptide (ANP) or atrial natriuretic factor, which is one of a family of hormones known to have an important role in salt and water homeostasis [2–6]. Natriuretic peptides are produced primarily in the heart but are also rele

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https://doi.org/10.1007/978-3-662-68783-3nes, either primary or secondary are thought to play a determining role in acute and chronic pathological disorders. The protein cytokines are a unique group of extracellular signalling molecules with critical roles in these processes. Cytokines (also termed growth factors) are pleiotrophic molecule

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