Titlebook: Aging in Cell and Tissue Culture; Proceedings of a sym Emma Hole?ková,Vincent J. Cristofalo (Associate Me Conference proceedings 1970 Plenu

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, of age-related changes in the proliferative capacity of cells in vitro. For example, cells derived from human fetal lung retain many properties of normal cells including a stable normal diploid karyotype and these cultures have been shown to have a limited life-span in vitro. In addi- tion, cultures derived978-1-4684-1823-1978-1-4684-1821-7

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Cell Strain Senescence in Vitro: Cell Culture Anomaly or an Expression of a Fundamental Inability oy of cells derived by dissociation of a given animal tissue. The second class, the so-called permanent cell lines, evolves during serial propagation of primary lines. We will be concerned mainly with the growth properties of primary cell lines in this discussion.

MANIA

d as part of this meeting was a symposium on "Aging in Cell and Tissue Culture." This volume contains the papers presented at that symposium. The use of cell and tissue culture techniques to study the mechanism of aging is not new. For example, it has long been known that age-associated changes whic

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Changes of the Latent Period of Explanted Tissues During Ontogenesis,loid cells in culture. This lifespan is longer for cells cultured from embryos than for cells cultured from mature donors. Both phenomena have been studied in our laboratory. This paper deals with our findings concerning the relationship between the latent period of fragment cultures from different rat organs and age.

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