Titlebook: Aging at the Molecular Level; Thomas Zglinicki (Professor of Cellular Gerontolog Book 2003 Springer Science+Business Media Dordrecht 2003

震驚

Oxidative Damage to Proteins,olites of molecular oxygen known as reactive oxygen species (ROS). The appropriate and inappropriate production of oxidants, together with the ability of organisms to respond to oxidative stress, is intricately connected to aging and life span.

ANTI

Mitochondria and Aging,n of protons across the membrane by complexes I,III and IV [2, 3]. This stored energy is then coupled to the formation of ATP by the controlled flow of protons down their chemical gradient within complex V, the ATP synthase.

THROB

Metabolic Regulation of Gene Silencing and Life Span,g, there is evidence that gene silencing may be important for determining lifespan. This chapter will provide an introduction to mechanisms of gene silencing and discuss how this (and related mechanisms) may influence longevity. There will be particular focus on how the environment and metabolic activity may regulate gene silencing and lifespan.

粗糙

Concrete

her contributions from an international team of authors, this volume will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutraceutical and health-care industry.978-90-481-6482-0978-94-017-0667-4

PANIC

refine

LATHE

Book 2003 field of study and research. The essential cause of aging is molecular damage that slowly overwhelms cellular and organismic defense, repair and maintenance systems. In recent years, a wealth of highly sophisticated research has transformed this idea from a credible hypothesis not only to a major t

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