Titlebook: Aerosol Inhalation: Recent Research Frontiers; Prodeedings of the I J. C. M. Marijnissen,L. Gradoń Book 1996 Kluwer Academic Publishers 199

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A Mechanistic Approach to Assessing the Lung Cancer Risk of Diesel Exhaust and Carbon Black, the data to assess human lung cancer risk. Current mechanistic data on the pathogenesis of lung cancer induced in rats by diesel soot and carbon black are reviewed. The mechanism of lung tumor induction in rats is apparently unique to high-level exposures, and a threshold relationship exists betwee

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Expostulate

Aerosol Delivery to the Respiratory tract in Experimental Animals,s, the inhaled dose can be calculated from a filter sample drawn in the breathing zone of the animal during exposure. Simultaneously the aerosol can be monitored in real-time to measure changes in the particle concentration. This is an advantage as the aerosol concentration can be adjusted during de

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The Challenge of the Epidemiologic Evidence for Excess Mortality and Morbidity Associated with Atmo air and rates of mortality and morbidity in populations exposed to concentrations below current USEPA standards and WHO-EURO air quality guidelines. When other known risk factors have been taken into account in regression analyses, it has been possible to show that daily changes of ambient particul

Excitotoxin

A Mechanistic Approach to Assessing the Lung Cancer Risk of Diesel Exhaust and Carbon Black,nment because of the widespread use of diesel engines. Carbon black is produced in large quantities and has many commercial uses around the world. Because the particle size of both materials is small, they are readily inhaled and deposited in the lung, giving rise to concern for induction of lung ca

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