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Titlebook: Advances in Peptic Ulcer Pathogenesis; W. D. W. Rees (Consultant Physician and Gastroente Book 1988 MTP Press Limited 1988 bacteria.epidem

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發(fā)表于 2025-3-21 17:50:03 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Advances in Peptic Ulcer Pathogenesis
影響因子2023W. D. W. Rees (Consultant Physician and Gastroente
視頻videohttp://file.papertrans.cn/150/149342/149342.mp4
圖書封面Titlebook: Advances in Peptic Ulcer Pathogenesis;  W. D. W. Rees (Consultant Physician and Gastroente Book 1988 MTP Press Limited 1988 bacteria.epidem
影響因子Over the past decade a great deal of research activity has occurred on either side of the gastroduodenal epithelial interface, with the common goal of elucidating the mechanisms of mucosal protection and how these may be compromised in peptic ulcer disease. A prime stimulus to such research has been the realization that abnormal acid secretion or its delivery into the duodenum in excessive amount cannot fully explain ulcer pathogenesis in the majority of patients. One may envisage the stomach and proximal duodenum as being in a dynamic equilibrium, with aggressive luminal factors, such as acid and pepsin, being counteracted by protective mucosal mechanisms. Until recently, the mechanisms involved in mucosal protection had been poorly defined while the physiology and pathophysiology of acid and pepsin secretion had been elucidated. The impression that gastroduodenal mucosa was protected by a single mechanism has at last been replaced by a more realistic view, suggesting a number of protective zones acting in series. Some of these zones may act as first or second line defences against aggressive factors while certain zones may specifically protect against certain aggressors.
Pindex Book 1988
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發(fā)表于 2025-3-21 22:54:05 | 只看該作者
https://doi.org/10.1007/978-94-011-4251-9c mucosal defence, reviews the studies of an association between changes in the microcirculation and changes in the capacity of the mucosa to resist injury and examines links between the microcirculation and acid peptic disease of the stomach.
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發(fā)表于 2025-3-22 04:09:34 | 只看該作者
on goal of elucidating the mechanisms of mucosal protection and how these may be compromised in peptic ulcer disease. A prime stimulus to such research has been the realization that abnormal acid secretion or its delivery into the duodenum in excessive amount cannot fully explain ulcer pathogenesis
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Book 1988 elucidating the mechanisms of mucosal protection and how these may be compromised in peptic ulcer disease. A prime stimulus to such research has been the realization that abnormal acid secretion or its delivery into the duodenum in excessive amount cannot fully explain ulcer pathogenesis in the maj
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發(fā)表于 2025-3-23 06:28:19 | 只看該作者
https://doi.org/10.1007/b137952us to either the measurement of ‘natural’ gastric acid secretion in response to a whole meal or the measurement of intragastric acidity (which is the end-result of not only gastric acid secretion, but also food and liquid taken by mouth and also gastric emptying).
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