Titlebook: Advances in Host-Directed Therapies Against Tuberculosis; Petros C. Karakousis,Richard Hafner,Maria Laura Ge Book 2021 Springer Nature Swi

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us malignancies and in primary bone sarcomas to evaluate the response after neoadjuvant therapy. Few data are available on its role in chordoma..In the following chapter, imaging features of sacral tumors are reviewed according to the different pathological entities.

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https://doi.org/10.1007/978-3-030-70497-1bolism by modulating the activity of sirtuins. Here, we briefly discuss the mammalian sirtuins with focus on the role of sirtuins during inflammation and fibrosis, which are cornerstones of TB pathogenesis. Finally, we highlight the importance of sirtuins as targets of TB host-directed therapies.

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berculosis, the leading cause of death by a single infectiouThis book discusses specific immune cell regulatory? pathway(s), immune cell types,? or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms in

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International Political Economy Seriessed in combination with standard antibiotics, as adjunctive therapy, to shorten treatment, prevent tissue damage, and prevent disease recurrence. Here we provide a general overview of the landscape of various HDTs currently in development for TB treatment.