Titlebook: Advanced Technologies for Protein Complex Production and Characterization; M. Cristina Vega Book 2016 The Editor(s) (if applicable) and Th

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Sumaya Gabriels,Natashia Muna,Kate le Rouxtimizing drug potency and selectivity. As it becomes increasingly evident, most disease relevant drug targets do not act as a single protein. In the body, they are instead generally found in complex with protein cofactors that are highly relevant for their correct function and regulation. This revie

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Biomedical and Computational Biologynge from low yield and poor solubility of a single-subunit enzyme to the wrong stoichiometry or the incomplete assembly of a multiprotein complex. Whatever the reason, overcoming the difficulties will take the researcher into a journey through the seemingly countless options that exist for protein e

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Polymer Science and Technology Seriesboratory level. Specifically, the developments made in the wake of these initiatives have revitalized the use of . as major host for heterologous protein expression. In parallel to these improvements for single expression, technologies for complex reconstitution by co-expression in . have been devel

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