| 期刊全稱 | Acute Myelogenous Leukemia in Childhood | | 期刊簡(jiǎn)稱 | Implications of Ther | | 影響因子2023 | Ursula Creutzig,J?rg Ritter,Günther Schellong | | 視頻video | http://file.papertrans.cn/145/144396/144396.mp4 | | 圖書封面 |  | | 影響因子 | The results of treatment for childhood acute myelogenous leukemia (AML) have improved considerably during the last ten years. This progress was demonstrated by the two consecutive multicenter studies, AML-BFM-78 and -83, in which almost identical extended multi drug regimes of che- motherapy were administered for eight weeks and followed up by two years maintenance. The main difference in the second study was the addition of an eight-day intensive in- duction course. Due to this new element, the relapse rate was reduced significantly. Another result of the BFM-83 study was the definition of two risk groups on the basis of standardized treatment, which has lead to a risk-adapted treatment strategy in the third ongoing trial, AML-BFM- 87. This improvement was only possible thanks to the coop- eration of pediatricians, physicians, radiotherapists, statisti- cians, and especially the staff at the hospitals and reference laboratories. Thus, we would like to thank everyone who has been involved in these studies and hope that they will be further encouraged to improve treatment strategies for AML in children. The coordination, enforcement, and analyses of the stud- ies would not have been | | Pindex | Book 1990 |
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