| 期刊全稱 | Actin Polymerization in Apicomplexan | | 期刊簡(jiǎn)稱 | A Structural, Functi | | 影響因子2023 | Avinash Kale | | 視頻video | http://file.papertrans.cn/145/144093/144093.mp4 | | 發(fā)行地址 | Reviews the mechanism of gliding motility in apicomplexan organisms.Discusses the structural, evolutionary, and functional role of actin-regulatory proteins.Introduces a mathematical model to help und | | 圖書(shū)封面 |  | | 影響因子 | .This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements...The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CPα and CPβ), cyclase-associated protein (CAP) and coronin 13–24 as potential drug targets against malaria.? As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design...Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics.?. | | Pindex | Book 2019 |
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