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Titlebook: Acoustic Levitation-Based Trace-Level Biosensing; Design of Detection Akihisa Miyagawa Book 2021 The Editor(s) (if applicable) and The Aut

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發(fā)表于 2025-3-21 18:48:09 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Acoustic Levitation-Based Trace-Level Biosensing
期刊簡稱Design of Detection
影響因子2023Akihisa Miyagawa
視頻videohttp://file.papertrans.cn/144/143972/143972.mp4
發(fā)行地址Nominated as an outstanding Ph.D. thesis by the Tokyo Institute of Technology.Proposes a novel trace detection concept based on a coupled acoustic-gravitational field.Analyzes the kinetics and thermod
學科分類Springer Theses
圖書封面Titlebook: Acoustic Levitation-Based Trace-Level Biosensing; Design of Detection  Akihisa Miyagawa Book 2021 The Editor(s) (if applicable) and The Aut
影響因子This book shows the availability and potential of the coupled acoustic-gravitational (CAG) field for trace-level biosensing. The proposed detection scheme also allows the evaluation of the kinetics and thermodynamics of the reaction occurring on a single microparticle (MP). This method has wide applicability in important fields, involving not only chemistry but also life, environmental, and medical sciences.?.The author proposes novel trace-level biosensing based on measurements of the levitation coordinate shift of an MP in the CAG field. The levitation coordinate of the MP in the CAG field is determined by its density and compressibility. The levitation coordinate shift is induced by the binding of gold nanoparticles (AuNPs) to the MP through interparticle reactions. Therefore, the quantity of molecules involved in the reaction can be determined from the levitation coordinate shift. The author demonstrates the zmol level detection for biotin, DNA/RNA, and organic molecules. In addition, the kinetics and thermodynamics are evaluated for various reactions occurring between the MP and AuNP, such as the avidin-biotin reaction, direct hybridization, sandwich hybridization, and aptamer
Pindex Book 2021
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沙發(fā)
發(fā)表于 2025-3-21 23:50:02 | 只看該作者
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https://doi.org/10.1007/978-3-658-18736-1d applications of ultrasound are discussed in Sect.?.. Particle separation and manipulation using external fields, such as dielectric, magnetic, electric, optical, thermal, and acoustic fields, are reviewed in Sects.?. and .. Finally, the purpose of this thesis is described in Sect.?..
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https://doi.org/10.1007/978-3-642-93709-5nchoring of target molecules on the microparticle or AuNP, which may lead to a change in the chemical and/or physical properties of the target molecules. In this chapter, a label-free detection scheme using DNA/RNA sandwich hybridization is demonstrated. In Sect.?., the effect of the bp number, invo
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發(fā)表于 2025-3-22 20:57:48 | 只看該作者
Hans-Jürgen M?ller,Norbert Müllerlecule with a specific sequence that selectively binds to a target. Aptamer DNA mediates the binding between PMMA and AuNPs to form AuNP-bound PMMA. When the target interacts with the aptamer, AuNP is released from the PMMA, which induces the levitation coordinate shift. This concept is confirmed fo
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發(fā)表于 2025-3-22 22:14:16 | 只看該作者
Acoustic Levitation-Based Trace-Level Biosensing978-981-16-1425-5Series ISSN 2190-5053 Series E-ISSN 2190-5061
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https://doi.org/10.1007/978-3-658-18736-1In this chapter, the principle of an acoustic radiation force and a combined acoustic-gravitational (CAG) field is discussed. From Sect.?. to Sect.?., the mathematical interpretation of the acoustic radiation force is described. Based on this, the principle of the CAG field is constructed in Sect.?..
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