| 期刊全稱 | ADP-Ribosylation of Proteins | | 期刊簡稱 | Enzymology and Biolo | | 影響因子2023 | Felix R. Althaus,Christoph Richter | | 視頻video | http://file.papertrans.cn/143/142717/142717.mp4 | | 學(xué)科分類 | Molecular Biology, Biochemistry and Biophysics‘ Molekularbiologie, Biochemie und Biophysik | | 圖書封面 |  | | 影響因子 | In 1966, a paper entitled "On the formation of a novel adenylylic compound by enzymatic extracts of liver nuclei" from Paul Mandel‘s laboratory in Strasbourg, France, planted the seed for a rapidly growing new field of biological research focusing on ADP-ribosylation reactions. The development of this field over the past 2 decades reflects very much a modern trend of biological research. As more detailed knowledge accumulates, enigmatic phenomena turn into concepts which create their own enigmata. This process tends to favor the development of multiple, seemingly disconnected, research lines until simplicity emerges from chaos and unifying concepts substitute for controversy. It appears that the field of ADP-ribosylation reactions has not yet attained this latter stage. For example, with the identification of two different classes of ADP-ribosylation reactions, i.e., mono-ADP-ribosyla- tion and poly-ADP-ribosylation reactions, the field split very early into two separate branches of research. With the present volume, we have divided the task of reviewing these two classes of ADP- ribosylation accordingly, although their coexistence in eukaryotes may involve a closer functional link | | Pindex | Book 1987 |
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