Titlebook: A Clinician‘s Guide to Sperm DNA and Chromatin Damage; Armand Zini,Ashok Agarwal Book 2018 Springer International Publishing AG 2018 Abort

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Statistics for Industry and Technology DNA fragmentation that provides the most relevant information for the clinicians and the patients alike. TUNEL test is fast becoming the assay of choice. In this chapter, we provide details on the measurement of sperm DNA fragmentation using a simple bench flow cytometer.

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M. Nikulin,L. Gerville-Réache,S. Orazio in different clinical applications on a global basis for more than a decade. The utility of the SCD test is further enhanced when it is conducted dynamically in analyzing sperm DNA longevity; when spermatozoa are incubated in vitro, it is possible to reveal underlying DNA damage that is not apparen

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Tomasz Rychlik,Magdalena Szymkowiakenotoxic. Therefore, it is important to minimize oxidative stress. This can either be achieved by elimination of conditions causing oxidative stress or by antioxidants. However, an oversupply of antioxidants in the body can cause the opposite condition of oxidative stress known as reductive stress,

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Yong Bao,Xiaotian Liu,Aman Ullahlium where the spermatogonial cells are found and differentiate toward the lumen where meiosis and spermatogenesis occur. During regular spermatogenesis, testicular germ cells can degenerate by an apoptotic process. The significance of regulating the cell population by apoptosis is more apparent whe

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https://doi.org/10.1007/978-3-030-62900-7espite that condensing proteins in spermatids may represent an impediment to this process. Insertion and deletions are expected to be created from the repair of mechanical or enzyme-induced breaks. Interestingly, from an evolutionary standpoint, the lower reliability of the repair process could also

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Tomasz Rychlik,Magdalena Szymkowiakal compartment in a process called spermatocytogenesis. After spermatocytogenesis, spermatids elongate to form spermatozoa by the process of spermiogenesis, a morphological development phase in which the nuclear transformations involving chromatin remodeling and compaction occur. Finally, spermatozo