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Tomasz Wi?liczr of the cell. It is generally assumed that Ca. enters the tubular cell at the luminal segment of the plasma membrane by a diffusional mechanism but that Ca. has to be transported actively out of the cell at the basolateral membrane against both a chemical gradient and membrane potential (Fig. 8.1).

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Masaaki Okubonnot determine whether it is useless or unnecessary; a paradox which is not uncommon in the history of science. As for the third charge of absurdity, it derives from the questionable proposition that things are by nature necessarily either qualitative or quantitative.

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