標(biāo)題: Titlebook: Uptake and Trafficking of Protein Toxins; Holger Barth Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusive license [打印本頁] 作者: crusade 時間: 2025-3-21 17:24
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作者: 名字 時間: 2025-3-21 22:53 作者: 真實的你 時間: 2025-3-22 00:27
Ralf Gerhardüberwiegend komplex berechnet. In Matrixschreibweise spiegelt sich das Zusammensetzen der Teilsysteme Lagerb?cke A, B mit Rotor S in der Bewegungsgleichung durch gekoppelte Blockmatrizen. In den Eigenschwingungen schwingt das System r?umlich. Bei Lager-Isotropie ist Instabilit?t m?glich; hinreichend作者: 填料 時間: 2025-3-22 05:20 作者: vibrant 時間: 2025-3-22 11:25 作者: 抱怨 時間: 2025-3-22 16:34 作者: 煞費苦心 時間: 2025-3-22 19:52
Katharina Ernst,Leonie Schnell,Holger Bartheniger Jahre erlangte, hat sich naturgem?? auch auf die Neuro-Traumatologie ausgewirkt. So ist nicht nur das Ausma? traumati- scher Hirnsch?den in der Akutphase klarer zu beurteilen, sondern auch die überwachung der posttraumatischen Verl?ufe ist um vieles exakter und sicherer geworden. Mit zunehmen作者: patriarch 時間: 2025-3-23 00:58
Roland Benz,Holger Barth Arzneimittel zu finden war; der Arzt kann hier, bevor er ein bestimmtes Medikament verordnet, nachschlagen, was bisher über die Nebenwirkungen des betreffenden Heilmittels bekannt- geworden ist. Er wird jedes Medikament besser anwenden k?nnen, wenn er au?er seinen Vorteilen auch seine Nachteile ken作者: cliche 時間: 2025-3-23 01:32
0070-217X s into the cytosol and therefore might lead to novel therapeutic strategies for toxin-associated diseases. These substances include pharmacological inhibitors of the host cell chaperones involved, as well as mu978-3-319-86502-7978-3-319-58893-3Series ISSN 0070-217X Series E-ISSN 2196-9965 作者: 虛構(gòu)的東西 時間: 2025-3-23 09:20 作者: Left-Atrium 時間: 2025-3-23 12:49
Uptake of Clostridial Neurotoxins into Cells and Dissemination, and undergoes a retrograde axonal transport to the spinal cord or brain, where the whole undissociated toxin is delivered and interacts with target neurons. Botulism most often results from ingestion of food contaminated with BoNT. Thus, BoNT passes through the intestinal epithelial barrier mainly 作者: construct 時間: 2025-3-23 14:58
Receptors and Binding Structures for , Toxins A and B,entry into host cells by redundant endocytotic pathways. Although both homologous toxins do obviously not share the same receptors, this principle of redundant binding domains found for TcdB does also account for TcdA.作者: 手段 時間: 2025-3-23 19:22
Cell Entry of C3 Exoenzyme from , ,cess to the intact cell. To date, no specific mechanism for internalization of C3 exoenzyme has been identified. Recently, vimentin was identified as membranous C3-binding partner involved in binding and uptake of C3. Although vimentin is not detected in neurons, vimentin is re-expressed after damag作者: chandel 時間: 2025-3-24 00:13 作者: 石墨 時間: 2025-3-24 03:22 作者: Biomarker 時間: 2025-3-24 09:03 作者: Diluge 時間: 2025-3-24 12:19
Book 2017ng chapters focus on compounds which inhibit the transport of the A subunits from endosomes into the cytosol and therefore might lead to novel therapeutic strategies for toxin-associated diseases. These substances include pharmacological inhibitors of the host cell chaperones involved, as well as mu作者: commodity 時間: 2025-3-24 14:59
Andreas Rummel?tzliche Koordinaten eingeführt werden. Linearisierte Kreiselgleichungen werden nach geeigneten Koordinatenumformungen mit Hilfe des Lagrange-Formalismus hergeleitet. Als Beispiel dient eine fliegend gelagerte Kreiselscheibe, für die freie und erzwungene Schwingungen reell und komplex berechnet und 作者: Infiltrate 時間: 2025-3-24 22:32 作者: NUL 時間: 2025-3-25 02:54
Ralf Gerhard?tzliche Koordinaten eingeführt werden. Linearisierte Kreiselgleichungen werden nach geeigneten Koordinatenumformungen mit Hilfe des Lagrange-Formalismus hergeleitet. Als Beispiel dient eine fliegend gelagerte Kreiselscheibe, für die freie und erzwungene Schwingungen reell und komplex berechnet und 作者: definition 時間: 2025-3-25 07:15 作者: 人類學(xué)家 時間: 2025-3-25 09:15 作者: 設(shè)想 時間: 2025-3-25 15:36
Bradley G. Stilesn Prozess involviert sind und Verantwortung für dessen gemeinsame Entwicklung übernehmen müssen. Abb. 2.1 zeigt die Wechselwirkung zwischen Hybridfahrzeug, Subsystem (bestehend aus den wesentlichen technischen Komponenten des Fahrzeuges) und ., welches jene ?u?eren Einflüsse beschreibt, die auf Fahr作者: Commemorate 時間: 2025-3-25 16:45 作者: MONY 時間: 2025-3-25 20:24 作者: 傷心 時間: 2025-3-26 01:57
Holger BarthProvides new insights into the development of tailored transport systems for the targeted drug delivery into mammalian cells.Reviews the key recent research on the role of cellular receptors, toxin po作者: electrolyte 時間: 2025-3-26 07:00 作者: hurricane 時間: 2025-3-26 11:49
https://doi.org/10.1007/978-3-319-58893-3Bordetella pertussis; Botulinum neurotoxins; Clostridium difficile; Clostridium perfringens toxin; Anthr作者: Meditate 時間: 2025-3-26 16:04 作者: Cytology 時間: 2025-3-26 19:59
Uptake and Trafficking of Protein Toxins978-3-319-58893-3Series ISSN 0070-217X Series E-ISSN 2196-9965 作者: Creatinine-Test 時間: 2025-3-27 00:05 作者: 阻止 時間: 2025-3-27 02:50 作者: 閑聊 時間: 2025-3-27 06:44 作者: Gobble 時間: 2025-3-27 10:59 作者: Isolate 時間: 2025-3-27 16:49
Receptors and Binding Structures for , Toxins A and B,First, these toxins are huge single-chain but multidomain proteins that display their action intracellularly within the cytosol of host cells. And second, albeit various cell types highly differ in their sensitivity toward these toxins, no toxin-resistant cell type has been described yet. Investigat作者: chapel 時間: 2025-3-27 18:29
Cell Entry of C3 Exoenzyme from , , downstream signaling pathways. It is used as pharmacological tool to study cellular Rho functions. In addition, C3bot harbors a transferase-independent activity on neurons to promote axonal and dendritic growth and branching. Many bacterial protein toxins interact specifically with proteins and/or 作者: Offbeat 時間: 2025-3-27 22:23
Receptor-Binding and Uptake of Binary Actin-ADP-Ribosylating Toxins,ase, which modifies actin thereby inhibiting actin polymerization, and a binding component that forms heptamers after proteolytic activation. While C2 toxin interacts with carbohydrate structures on host cells, the group of iota-like toxins binds to lipolysis-stimulated lipoprotein receptor 作者: 小木槌 時間: 2025-3-28 05:46
,Clostridial Binary Toxins: Basic Understandings that Include Cell Surface Binding and an Internal “, . and . are one group of enteric-acting toxins that attack the actin cytoskeleton of various cell types. These enterotoxins consist of A (enzymatic) and B (cell binding/membrane translocation) components that assemble on the targeted cell surface or in solution, forming a multimeric complex. Once 作者: Abrupt 時間: 2025-3-28 09:29 作者: cleaver 時間: 2025-3-28 11:33
Multivalent Inhibitors of Channel-Forming Bacterial Toxins,ng multiple finely-tuned points of contact between multivalent ligands and their supposed multivalent targets. Here, we describe several prominent examples where the multivalent blockers were investigated for their ability to directly obstruct oligomeric channel-forming bacterial exotoxins, such as 作者: 舊石器時代 時間: 2025-3-28 18:17
Toxin Transport by A-B Type of Toxins in Eukaryotic Target Cells and Its Inhibition by Positively Cax toxin of . and the different A-B type clostridial toxins that are the causative agents of severe human and animal diseases and could serve as biological weapons. The components of all these toxins comprise one binding/transport (B) subunit and one or two separate, non-linked enzymatically active 作者: alabaster 時間: 2025-3-28 20:22
Book 2017inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of .Clostridium botulinum. neurotoxins, .Clostridium botulinum. C3 toxin, .Clostridium difficile. toxins, binary clostridial enterotoxins, anthrax toxins and dipht
