標(biāo)題: Titlebook: Subarachnoid Hemorrhage; Neurological Care an Robert D. Martin,Warren Boling,John H. Zhang Book 2020 Springer Nature Switzerland AG 2020 Ce [打印本頁] 作者: 叛亂分子 時(shí)間: 2025-3-21 20:09
書目名稱Subarachnoid Hemorrhage影響因子(影響力)
作者: Axillary 時(shí)間: 2025-3-21 20:43 作者: 四溢 時(shí)間: 2025-3-22 01:39
Kenji Kanamaruhe receptors, and ultimately the actions of the retinoid-humoral system. It is therefore truly important to know the precise concentrations and exact nature of the retinoids present at definite times and specific loci during development, and indeed, during any event mediated by retinoids. To determi作者: narcotic 時(shí)間: 2025-3-22 07:27 作者: gruelling 時(shí)間: 2025-3-22 12:16 作者: 拱形面包 時(shí)間: 2025-3-22 15:38
han inductive reasoning. Because of this it is not infrequent that we are presented with compounds that are therapeutically effective but whose mode of action remains mysterious. It is worthwhile bearing in mind that it is only in the past 20 or 30 years that we have understood how digitalis and mor作者: Champion 時(shí)間: 2025-3-22 19:37 作者: 乳汁 時(shí)間: 2025-3-22 22:50 作者: 大雨 時(shí)間: 2025-3-23 05:00 作者: Fillet,Filet 時(shí)間: 2025-3-23 08:53
Jinjin Wang,Yin Liu,Haitao Shen,Haiying Li,Zhong Wang,Gang Chenical targets and current drug development paradigms are largely based on their nuclear transcription mechanism (genomic action). However, the side effects and limited therapeutic efficacy of retinoid-like drugs with such strategy remain a problem in clinical practice. Increasing evidences have demon作者: 原諒 時(shí)間: 2025-3-23 10:25
Fumi Nakano,Fumihiro Kawakita,Lei Liu,Yoshinari Nakatsuka,Hirofumi Nishikawa,Takeshi Okada,Masato Shkey regulators of gene expression, retinol being oxidized via a retinaldehyde intermediate to retinoic acid (RA) which activates specific nuclear receptors, the signalling of which is turned off by oxidative inactivation of the ligand to 4-oxo-RA and other metabolites. Many of these retinoids are pr作者: 最小 時(shí)間: 2025-3-23 14:44 作者: FRONT 時(shí)間: 2025-3-23 21:34
Hirofumi Nishikawa,Fumi Nakano,Lei Liu,Yoshinari Nakatsuka,Takeshi Okada,Masato Shiba,Hidenori Suzukdecrease the toxic side effects associated with retinoid therapy. Retinoids are known to mediate many different biological processes, including cellular differentiation and proliferation, epithelial homeostasis, immunocompetence, and embryogenesis (. et al. 1994; .-. 1992). Currently, retinoids are 作者: conjunctivitis 時(shí)間: 2025-3-24 00:27
Yuchun Zuo,Tibiao He,Peiqiang Liao,Kai Zhuang,Xiaoxin Yan,Fei Liudecrease the toxic side effects associated with retinoid therapy. Retinoids are known to mediate many different biological processes, including cellular differentiation and proliferation, epithelial homeostasis, immunocompetence, and embryogenesis (. et al. 1994; .-. 1992). Currently, retinoids are 作者: 辭職 時(shí)間: 2025-3-24 04:50 作者: Paleontology 時(shí)間: 2025-3-24 09:47 作者: 細(xì)胞 時(shí)間: 2025-3-24 14:27
Hidenori Suzuki,Masashi Fujimoto,Fumihiro Kawakita,Lei Liu,Fumi Nakano,Hirofumi Nishikawa,Takeshi Okltaneous fitting of single i. v. and oral data to a three-compartment model assuming first-order absorption was possible. Using Nonlin parameter estimates of the single-dose data, one is able to predict the decline in plasma levels of parent drug following cessation of a 10 days multiple dosing regi作者: 極少 時(shí)間: 2025-3-24 15:06 作者: 生來 時(shí)間: 2025-3-24 22:52 作者: 運(yùn)動(dòng)的我 時(shí)間: 2025-3-25 00:46
Zhiyuan Vera Zheng,Ping Kuen Lam,Wai Sang Poon,Kwok Chu George Wong a major homeostatic role. The authors of this monograph have provided an overview of the current understanding of retinoid biology with particular reference to the use of this class of agents in the prevention and treatment of malignancy. It is clear from the discussions in this book that, although作者: 歡笑 時(shí)間: 2025-3-25 06:30
Heparin Treatment in Aneurysmal Subarachnoid Hemorrhage: A Review of Human Studies,ciated with significant hemorrhagic complications; however, vigilance is essential for early detection of heparin-induced thrombocytopenia in order to prevent devastating sequelae. Multicenter randomized controlled trials are necessary for objective characterization of the effects of heparin.作者: Encoding 時(shí)間: 2025-3-25 10:32 作者: MILL 時(shí)間: 2025-3-25 12:29 作者: 虛弱 時(shí)間: 2025-3-25 17:36 作者: 業(yè)余愛好者 時(shí)間: 2025-3-25 21:46 作者: nonplus 時(shí)間: 2025-3-26 00:28 作者: abolish 時(shí)間: 2025-3-26 04:29
Subarachnoid Hemorrhage,Related Epilepsy,ly increases mortality rates in those who are affected. The development of epilepsy from subarachnoid hemorrhage (SAH) has an important negative impact on long-term survival, functional status, and cognitive recovery in patients following aneurysmal rupture. Anticonvulsant medication (AED) administr作者: paroxysm 時(shí)間: 2025-3-26 10:02 作者: 調(diào)色板 時(shí)間: 2025-3-26 13:44 作者: 防止 時(shí)間: 2025-3-26 18:14
Possible Involvement of Caspase-Independent Pathway in Neuronal Death After Subarachnoid Hemorrhage euronal apoptosis is one of the constituents of early brain injury. Caspase family is popular proteases in apoptotic pathways, but there also exist caspase-independent cell death pathways in many pathologic states. In this study, we investigated the ratio of caspase-related and caspase-unrelated neu作者: nitric-oxide 時(shí)間: 2025-3-26 23:47
Nox2 and Nox4 Participate in ROS-Induced Neuronal Apoptosis and Brain Injury During Ischemia-Reperfute in brain damage caused by ischemia-reperfusion (I/R). The aim of this study is to investigate the effects of specific chemical inhibitors of Nox2 and Nox4 on cerebral I/R-induced brain injury in rats...: At 0.5?h before MCAO surgery, the rats were pretreated with vehicle, Nox2 inhibitor (gp91ds-t作者: figment 時(shí)間: 2025-3-27 03:08
Link Between Receptors That Engage in Developing Vasospasm After Subarachnoid Hemorrhage in Micerotein and reported to increase in spastic cerebral artery wall after SAH, is a ligand for both Toll-like receptor 4 (TLR4) and epidermal growth factor receptor (EGFR). Our previous studies suggested the involvement of TNC and these receptors in vasoconstriction or vasospasm after SAH. In this study作者: 不透氣 時(shí)間: 2025-3-27 08:04 作者: Arresting 時(shí)間: 2025-3-27 11:21 作者: Fibrinogen 時(shí)間: 2025-3-27 17:12
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Sughlighted with inflammation occurs early after SAH. As the main cause of DCI, microthrombosis associated with the prognosis of SAH. The aim of this study was to show HSP90 inhibitor 17-AAG effect on microthrombosis after SAH in rats...: Ninety-five SD rats were used for the experiment. For time cour作者: confederacy 時(shí)間: 2025-3-27 21:17 作者: 比目魚 時(shí)間: 2025-3-28 01:53
Subarachnoid Hemorrhage Pattern Predicts Acute Cerebral Blood Flow Response in the?Ratlot better predicts the development of delayed cerebral ischemia and poor outcomes. In a rodent model of acute SAH, we directly measured the effects of the volume of blood injected versus the pattern of distribution of hemorrhage in the subarachnoid space on markers of early brain injury, namely, ce作者: 盡責(zé) 時(shí)間: 2025-3-28 02:33
Toll-Like Receptor 4 and Tenascin-C Signaling in Cerebral Vasospasm and Brain Injuries After Subaracamily members. TLR4 can be activated by many endogenous ligands having damage-associated molecular patterns including heme and fibrinogen at the rupture of a cerebral aneurysm, and therefore its activation is reasonable as an initial step of cascades to brain injuries after aneurysmal subarachnoid h作者: 嗎啡 時(shí)間: 2025-3-28 06:36
Spreading Depolarization during the Acute Stage of Experimental Subarachnoid Hemorrhage in Miceole of SD during the acute phase of SAH is still unclear. The objective of this study was to investigate (a) the occurrence of SD with intrinsic optical signal (IOS) imaging, (b) the effect of ketamine on SD, and (c) the resulting brain edema (brain water content (BWC)) during the acute stage of exp作者: 規(guī)范要多 時(shí)間: 2025-3-28 12:16
The PERK Pathway Plays a Neuroprotective Role During the Early Phase of Secondary Brain Injury Inducf pathophysiological processes of neurological diseases. However, few studies have investigated the role of the PERK in intracerebral hemorrhage (ICH). The present study evaluated the role of the PERK pathway during the early phase of ICH-induced secondary brain injury (SBI) and its potential mechan作者: 標(biāo)準(zhǔn) 時(shí)間: 2025-3-28 17:26
The Time Course of Cognitive Deficits in Experimental Subarachnoid Hemorrhageve deficits. To enrich the pre-clinical research on the neurological deficits after SAH, we investigate the temporal cognitive deficits and the longitudinal course of cognitive recovery in endovascular perforation SAH murine model. The SAH mice show reproducible body weakness and headache-symbolized作者: Alveoli 時(shí)間: 2025-3-28 20:00
0065-1419 l trials, academic and industrial interactions.Discusses ani.This book highlights the latest developments in acute and delayed neurovascular injury studies including delayed cerebral vasospasm, early brain injury, micro-circulation compromise, spreading cortical depolarization, neuroinflammation, an作者: Eclampsia 時(shí)間: 2025-3-29 02:31 作者: 連接 時(shí)間: 2025-3-29 04:50
Book 2020ry, micro-circulation compromise, spreading cortical depolarization, neuroinflammation, and long-term cognitive dysfunctions after subarachnoid hemorrhage. About 32 chapters cover original presentations from the 14.th. international conference on neurovascular events after subarachnoid hemorrhage, h作者: V洗浴 時(shí)間: 2025-3-29 10:11 作者: bourgeois 時(shí)間: 2025-3-29 13:47 作者: 愛社交 時(shí)間: 2025-3-29 17:44
The Time Course of Cognitive Deficits in Experimental Subarachnoid Hemorrhageort-term and long-term memory. The cognitive deficits occur mostly in the early phase and recover gradually till day 10 after SAH. The systematical assessments of cognitive function after experimental aneurysmal SAH elucidate the time course of cognitive deficits and provide the time window of potential interventions.作者: 小卒 時(shí)間: 2025-3-29 23:42
Acta Neurochirurgica Supplementhttp://image.papertrans.cn/t/image/881239.jpg作者: emulsify 時(shí)間: 2025-3-30 00:25
https://doi.org/10.1007/978-3-030-04615-6Cerebral Vasospasm; Early Brain Injury; Acute Neurovascular Event; Delayed Cerebral Vasospasm; Neuroinfl作者: Needlework 時(shí)間: 2025-3-30 08:04 作者: LAST 時(shí)間: 2025-3-30 09:47
Robert D. Martin,Warren Boling,John H. ZhangSummarizes the latest studies on acute and delayed neurovascular injuries after subarachnoid hemorrhage.Covers new pilot treatments, clinical trials, academic and industrial interactions.Discusses ani作者: Heresy 時(shí)間: 2025-3-30 13:22
Springer Nature Switzerland AG 2020作者: Ruptured-Disk 時(shí)間: 2025-3-30 17:23 作者: 蝕刻術(shù) 時(shí)間: 2025-3-30 21:58
oxy RA, 4-oxo RA, and 1%hydroxy RA. 13-. RA also binds to RARs, but with a .. value higher than the former group. Retinol can also induce responses in RA-sensitive systems; generally at doses ~200-fold higher than RA. In RA-dependent responses, retinol probably functions through conversion into RA (作者: organic-matrix 時(shí)間: 2025-3-31 02:02 作者: Chagrin 時(shí)間: 2025-3-31 06:13
Kenji Kanamaruoxy RA, 4-oxo RA, and 1%hydroxy RA. 13-. RA also binds to RARs, but with a .. value higher than the former group. Retinol can also induce responses in RA-sensitive systems; generally at doses ~200-fold higher than RA. In RA-dependent responses, retinol probably functions through conversion into RA (作者: Medley 時(shí)間: 2025-3-31 11:07 作者: BALK 時(shí)間: 2025-3-31 16:54
Warren Boling,Lydia Kore(as with the corticosteroids). This is certainly the case with the retinoids. Here are drugs that are active in psoriasis (plaque type, erythro-dermic, pustular and arthropathic), the disorders of keratinization (including the ichthyotic disorders, erythrokeratoderma variabilis and Darier’s disease)作者: arthroscopy 時(shí)間: 2025-3-31 21:32
(as with the corticosteroids). This is certainly the case with the retinoids. Here are drugs that are active in psoriasis (plaque type, erythro-dermic, pustular and arthropathic), the disorders of keratinization (including the ichthyotic disorders, erythrokeratoderma variabilis and Darier’s disease)作者: GRATE 時(shí)間: 2025-3-31 21:56
Alejandra N. Martinez,Crissey L. Pascale,Peter S. Amenta,Rachel Israilevich,Aaron S. Dumont der Rhee ... regularly measured the height and urinary hydroxyproline excretion in five children during treatment with etretinate. No signs of growth retardation were found for the treatment periods studied (varying between 11 and 17 months). Tamayo and Ruiz-Maldonado. concluded from their experien作者: extinct 時(shí)間: 2025-4-1 05:55 作者: 象形文字 時(shí)間: 2025-4-1 09:00
Fumi Nakano,Lei Liu,Fumihiro Kawakita,Yoshinari Nakatsuka,Hirofumi Nishikawa,Takeshi Okada,Masato Shn of additional nuclear receptors that partner with RXR. Because rexinoids often exhibit selectivity for RXR activation, versus activating the retinoic-acid-receptor (RAR), rexinoid treatment avoids the cutaneous toxicity commonly associated as a side effect with retinoids. There are many examples o作者: Cocker 時(shí)間: 2025-4-1 14:10
Jinjin Wang,Yin Liu,Haitao Shen,Haiying Li,Zhong Wang,Gang Chentumor suppressive effect. This chapter provides methodology for identification of acacetin as a ligand and regulator of non-genomic signaling of RARγ. These laboratory protocols should be helpful for those researchers and beginners who are passionate about identifying chemical leads to probe the non作者: menopause 時(shí)間: 2025-4-1 17:39
Fumi Nakano,Fumihiro Kawakita,Lei Liu,Yoshinari Nakatsuka,Hirofumi Nishikawa,Takeshi Okada,Masato Shous system. Similarly, a patterned distribution of RA controls function of the adult CNS, a tissue particularly difficult to analyse for RA because of its high lipid content. To understand how these patterns are organized in the brain and change over time, it is essential to determine the concentrat作者: 政府 時(shí)間: 2025-4-1 20:19 作者: A精確的 時(shí)間: 2025-4-1 23:45
Hirofumi Nishikawa,Fumi Nakano,Lei Liu,Yoshinari Nakatsuka,Takeshi Okada,Masato Shiba,Hidenori Suzukcan be developed. The probability of finding retinoids with better therapeutic indices has increased dramatically in the past few years because our understanding of the molecular mechanisms of retinoid action has progressed rapidly since the discovery of the six known retinoid receptors, RARα, RARβ,
