標(biāo)題: Titlebook: Sodium Channels, Pain, and Analgesia; Michael J. Parnham (Senior Scientific Advisor),Kev Book 2005 Birkh?user Basel 2005 Nervous System.So [打印本頁] 作者: cerebral 時(shí)間: 2025-3-21 17:28
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作者: Crohns-disease 時(shí)間: 2025-3-21 20:40
Sodium Channels, Pain, and Analgesia978-3-7643-7411-2Series ISSN 1422-7746 Series E-ISSN 2296-4525 作者: 轎車 時(shí)間: 2025-3-22 03:50
Michael J. Parnham (Senior Scientific Advisor),KevWritten by well-known scientists in their respective fields.The Nav1.8 sodium channel is discussed.Provides current opinion and future direction.Includes supplementary material: 作者: Proclaim 時(shí)間: 2025-3-22 04:47
Progress in Inflammation Researchhttp://image.papertrans.cn/s/image/870395.jpg作者: 努力趕上 時(shí)間: 2025-3-22 09:20 作者: 蝕刻 時(shí)間: 2025-3-22 14:50 作者: Keratin 時(shí)間: 2025-3-22 18:49 作者: 擔(dān)心 時(shí)間: 2025-3-23 00:54
Future directions in sodium channel research, all may amplify the repertoire of voltage-gated sodium channels. Using adult inducible knockouts of the various components of sodium channel complexes should provide invaluable information for defining new targets for therapeutic intervention in a much more efficient way than conventional pharmacology allows.作者: Irksome 時(shí)間: 2025-3-23 01:28 作者: 搖曳 時(shí)間: 2025-3-23 08:15 作者: Sciatica 時(shí)間: 2025-3-23 11:48 作者: 火花 時(shí)間: 2025-3-23 14:16 作者: orthopedist 時(shí)間: 2025-3-23 18:17
NaV1.8 as a drug target for pain,ciceptive neurons continues to be regarded as an important contributory event to the onset and/or maintenance of the pain state. As such, molecules that determine nociceptor signalling are prime targets for development of analgesic drugs. Na.1.8 is one of these molecules since (1) its expression is 作者: BRAVE 時(shí)間: 2025-3-24 01:27
Role of voltage-gated sodium channels in oral and craniofacial pain,ars indicates that the biophysical properties, expression pattern and/or distribution of VGSCs are subject to change and that such changes underlie pain associated with injury. The majority of this evidence has come from study of spinal afferents where specific patterns of changes in VGSCs have been作者: 冒號(hào) 時(shí)間: 2025-3-24 06:12
Future directions in sodium channel research,l excitability in response to external cues. Splice variants, channel editing, post-translational modification and association with accessory proteins all may amplify the repertoire of voltage-gated sodium channels. Using adult inducible knockouts of the various components of sodium channel complexe作者: 殺子女者 時(shí)間: 2025-3-24 09:08
Voltage-gated sodium channels and pain associated with nerve injury and neuropathies,作者: 高歌 時(shí)間: 2025-3-24 13:45 作者: 傻 時(shí)間: 2025-3-24 17:48 作者: 責(zé)難 時(shí)間: 2025-3-24 19:58
Lodewijk V. Dekker,David Cronktrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was give978-94-010-5157-6978-94-011-2618-2Series ISSN 1389-2185 作者: 虛構(gòu)的東西 時(shí)間: 2025-3-25 01:59 作者: OTTER 時(shí)間: 2025-3-25 07:10
Andreas Scholztrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was give978-94-010-5157-6978-94-011-2618-2Series ISSN 1389-2185 作者: Exaggerate 時(shí)間: 2025-3-25 10:02 作者: 迅速飛過 時(shí)間: 2025-3-25 14:42 作者: Oratory 時(shí)間: 2025-3-25 16:52
Book 2005The final chapter highlights the functional diversity of sodium channels in part provided by post-transcriptional processing and the insights into sodium channel function that are being provided by tissue specific and inducible gene knock-out technology..作者: Jacket 時(shí)間: 2025-3-26 00:02 作者: Largess 時(shí)間: 2025-3-26 01:13
Sodium channels and nociceptive nerve endings,ry pain. For example, increased expression of both TTX-sensitive and TTX-resistant Na. channels may also contribute to lowering the voltage threshold and changing the firing characteristics of nociceptive nerve endings..Based on current evidence, selective blockade of Na. channel subtypes, in partic作者: carotenoids 時(shí)間: 2025-3-26 06:43
NaV1.8 as a drug target for pain,is now a feasible drug target with cell lines being developed that allow high-throughput screening of Na.1.8 in a physiological context and screening technology being available to measure sodium channel activity in high-throughput functional assays. However, ultimately only the availability of drugs作者: notice 時(shí)間: 2025-3-26 12:19 作者: 津貼 時(shí)間: 2025-3-26 13:23
metric analysis can readily be expanded for analysis of other lipid classes not mentioned as long as appropriate sample preparation is conducted, and should aid researchers in the field to better understand and manage the technology for analysis of cellular lipidomes.作者: 外表讀作 時(shí)間: 2025-3-26 19:26 作者: Processes 時(shí)間: 2025-3-27 00:58 作者: 乏味 時(shí)間: 2025-3-27 02:12
Kenji Okuse,Mark D. Bakerative samples and generate absolute concentration information on metabolites for which the standards are available. Combined with statistical analysis and metabolite identification tools, this method can be used to identify key metabolites involved in differentiating comparative samples such as dise作者: Ordeal 時(shí)間: 2025-3-27 05:46 作者: PURG 時(shí)間: 2025-3-27 10:37 作者: 云狀 時(shí)間: 2025-3-27 15:44
John N. Woodethylated alditol acetates (PMAAs). The following paper reviews the major literature pertaining to the specific protocol for linkage analysis of carbohydrates outlined herein. The review details additional steps necessary for the completion of uronic acid linkage analysis, as well as analysis of chi作者: transplantation 時(shí)間: 2025-3-27 17:52 作者: 體貼 時(shí)間: 2025-3-28 01:08
s practices due to its high efficiency, sensitivity, and reproducibility, as well as its broad coverage. This platform has been broadly used to determine the altered content and/or composition of lipid classes, subclasses, and individual molecular species induced by diseases, genetic manipulations, 作者: maladorit 時(shí)間: 2025-3-28 05:24 作者: Memorial 時(shí)間: 2025-3-28 09:06 作者: Exonerate 時(shí)間: 2025-3-28 13:41 作者: 提升 時(shí)間: 2025-3-28 17:20
Kenji Okuse,Mark D. Bakeraccuracy. Herein we describe a high-performance CIL LC-MS method for generating quantitative and comprehensive profiles of the metabolome for metabolomics applications. After mixing two comparative samples separately labeled by light or heavy isotopic tags through chemical reactions, the peak intens作者: FLINT 時(shí)間: 2025-3-28 21:44 作者: Crepitus 時(shí)間: 2025-3-29 02:19 作者: 籠子 時(shí)間: 2025-3-29 04:30 作者: Incorruptible 時(shí)間: 2025-3-29 09:59
Michael S. Gold achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhan作者: 頌揚(yáng)國家 時(shí)間: 2025-3-29 12:37
Andreas Scholz achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhan
