標(biāo)題: Titlebook: Small Molecule Microarrays; Methods and Protocol Mahesh Uttamchandani,Shao Q. Yao Book 2017Latest edition Springer Science+Business Media N [打印本頁] 作者: 劉興旺 時(shí)間: 2025-3-21 18:36
書目名稱Small Molecule Microarrays影響因子(影響力)
作者: Malaise 時(shí)間: 2025-3-21 22:04
Avijit K. Adak,Ting-Wei Lin,Ben-Yuan Li,Chun-Cheng Lin作者: 剝削 時(shí)間: 2025-3-22 01:45
Caterina Zilio,Laura Sola,Marina Cretich,Anna Bernardi,Marcella Chiari作者: Expertise 時(shí)間: 2025-3-22 06:48
Ping Wang,Liqian Gao,Haipeng Lei,Su Seong Lee,Shao Q. Yao,Hongyan Sun作者: 佛刊 時(shí)間: 2025-3-22 11:15
Zhenkun Na,Sijun Pan,Mahesh Uttamchandani,Shao Q. Yao作者: congenial 時(shí)間: 2025-3-22 16:56
Colleen M. Connelly,Fardokht A. Abulwerdi,John S. Schneekloth Jr.作者: instill 時(shí)間: 2025-3-22 19:38 作者: Pituitary-Gland 時(shí)間: 2025-3-22 22:49
Moon-Hyeong Seo,Satra Nim,Jouhyun Jeon,Philip M. Kim作者: patriarch 時(shí)間: 2025-3-23 02:28
Fabrication of Bio-function-Preserved Saccharide Microarray Chips with Cyanuric Chloride as a Rotatn hydroxyl-terminated surfaces. This facilitates the second chlorine on one of the upper “Y-branch” to react with saccharides at ca. 25 °C, a very convenient room temperature for practical manipulation. The third chlorine can further react with saccharides but at ca. 50 °C which is not too difficult作者: arbovirus 時(shí)間: 2025-3-23 09:37
Fabrication of Carbohydrate Microarrays by Boronate Formation,vatized with high-affinity boronic acid ligands. The immobilized ligands in these microarrays maintain the receptor-binding activities including those of lectins and antibodies according to the structures of their pendant carbohydrates for rapid analysis of a number of carbohydrate-recognition event作者: 敏捷 時(shí)間: 2025-3-23 12:58 作者: 感情 時(shí)間: 2025-3-23 15:50 作者: Macronutrients 時(shí)間: 2025-3-23 20:25
Label-Free Sensing on Microarrays,ensors, to a certain extent, take the place of fluorescent methods by providing a comparable sensitivity as well as retaining the conformational and functional integrality of biomolecules to be investigated. More importantly, some of these biosensors are capable of real-time monitoring probe–target 作者: 陶瓷 時(shí)間: 2025-3-23 23:56
Profiling Phosphopeptide-Binding Domain Recognition Specificity Using Peptide Microarrays, chemical properties of the domain binding surface that, aside from offering a hydrophilic pocket for the phosphorylated residue, shows preference for specific sequences. Although the protein structure and the cell context are also important to ensure specificity, the amino acid sequence flanking th作者: laceration 時(shí)間: 2025-3-24 04:29
Validation Procedure for Multiplex Antibiotic Immunoassays Using Flow-Based Chemiluminescence Micro the European Communities 2002/657/EC) for multiplex immunoassays performed as flow-through chemiluminescence microarrays, using the example of a small molecule microarray for the simultaneous detection of 13 antibiotics in milk. By this means, we suggest to accept multianalyte immunoassays as confi作者: Sciatica 時(shí)間: 2025-3-24 08:23
Synthetic Glycan Microarrays, custom glycan microarrays that are used to examine glycan–GBP binding specificities. Conjugation-ready synthetic glycans are covalently attached to microarray surfaces through nucleophilic linker moieties. Microarrays are incubated with GBPs, and binding events are quantitatively detected by fluore作者: Chipmunk 時(shí)間: 2025-3-24 12:37 作者: 皮薩 時(shí)間: 2025-3-24 14:51 作者: connoisseur 時(shí)間: 2025-3-24 21:33 作者: Fester 時(shí)間: 2025-3-25 02:57 作者: BYRE 時(shí)間: 2025-3-25 06:01
The Expanding World of Small Molecule Microarrays,nal screening throughput and versatility. The concept at the heart of the technology is elegant, yet simple: by presenting large collections of molecules in high density on a flat surface, one is able to interrogate all possible interactions with desired targets, in just a single step. SMMs have bec作者: 吹牛者 時(shí)間: 2025-3-25 09:05
Novel Substrates for Microarrays,nal substrates such as glass and nitrocellulose often entail complicated preparation processes such as the activation and functionalization of the reaction spots and surface blocking to prevent nonspecific molecule adsorption. In addition, coffee-ring morphology of the spots is a common issue in the作者: Obsessed 時(shí)間: 2025-3-25 14:26
Fabrication of Bio-function-Preserved Saccharide Microarray Chips with Cyanuric Chloride as a Rotatroblems, which have led to many strategies proposed but nearly none can immobilize small saccharides without losing their bio-affinity. Herein introduced is an easy strategy able to directly immobilize all intact saccharides on solid surface with excellent preservation of their molecular recognition作者: 記憶法 時(shí)間: 2025-3-25 17:25 作者: 舊石器時(shí)代 時(shí)間: 2025-3-26 00:02 作者: sundowning 時(shí)間: 2025-3-26 01:03 作者: Hippocampus 時(shí)間: 2025-3-26 06:39
Label-Free Sensing on Microarrays,f thousands of biomolecular interactions simultaneously, facilitating the functional characterization of these biomolecules in areas of genomics, proteomics, glycomics, and cytomics. Routinely, analysis of binding reactions between solution-phased probes and surface-immobilized targets involves some作者: 鐵塔等 時(shí)間: 2025-3-26 10:03
Optical Microscopy for Detecting Binding on Small Molecule Microarrays, simultaneous detection of up to thousands of biological interactions. Conventional detection technique employed in SMMs is fluorescence spectroscopy. However, the possibility of fluorescent labels affecting the binding properties of small molecules drives the development of label-free screening tec作者: 黑豹 時(shí)間: 2025-3-26 15:06
Array-on-Array Strategy For Activity-Based Enzyme Profiling,ts of spotting a first array with large droplets of enzymes with varying concentrations and subsequently spotting a second array with small droplets of fluorogenic substrate on top of the enzyme array. By varying the array on array spotting patterns of different classes of enzyme (e.g., proteases, p作者: 平 時(shí)間: 2025-3-26 17:37
,Protein–Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays,action networks, to molecular fingerprinting and small molecular inhibitor discovery. The technique has significantly impacted both basic and applied research. The microarray platform can likewise enable high-throughput screening and discovery of protein–protein interaction (PPI) inhibitors. Herein 作者: Ancestor 時(shí)間: 2025-3-26 23:00
Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays,ease states. One such approach is the use of small molecule microarrays (SMMs). Typically, SMMs are generated by spatially arraying and covalently linking a library of small molecules to a glass surface. Next, incubation of the arrays with a fluorescently labeled RNA reveals binding interactions tha作者: 裝飾 時(shí)間: 2025-3-27 03:23
Profiling Phosphopeptide-Binding Domain Recognition Specificity Using Peptide Microarrays,ns are regulated by covalent posttranslational modifications such as phosphorylation and acetylation. These modifications can change the chemical nature of the interaction interfaces and modulate the binding affinity of the interacting partners. In signal transduction, the most frequent modification作者: 下級 時(shí)間: 2025-3-27 06:22
Validation Procedure for Multiplex Antibiotic Immunoassays Using Flow-Based Chemiluminescence Microegard to multiplex quantification, these tests can be performed as chemiluminescence microarray immunoassays, in which, in principle, the analyte in the sample and the same substance immobilized on the chip surface compete for a limited number of specific antibody binding sites. The amount of the sp作者: Invigorate 時(shí)間: 2025-3-27 13:20 作者: DEVIL 時(shí)間: 2025-3-27 17:36 作者: 的闡明 時(shí)間: 2025-3-27 21:51 作者: Armada 時(shí)間: 2025-3-27 22:10 作者: VEST 時(shí)間: 2025-3-28 03:14
Large-Scale Interaction Profiling of Protein Domains Through Proteomic Peptide-Phage Display Using lay (ProP-PD). In this chapter, we describe protocols for phage display for the identification of natural peptide binders for a given protein. We finally describe deep sequencing for the analysis of the proteomic peptide-phage display.作者: 高度 時(shí)間: 2025-3-28 08:00
Screening Mammalian Cells on a Hydrogel: Functionalized Small Molecule Microarray, preparation of mammalian cell-based microarrays using selectively captured of human prostate cancer cells (PC-3). This platform was then used in controlled drug release and measuring the associated drug effects on these cancer cells.作者: 平庸的人或物 時(shí)間: 2025-3-28 12:33 作者: 我們的面粉 時(shí)間: 2025-3-28 16:34 作者: CERE 時(shí)間: 2025-3-28 19:09
,Protein–Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays,ls. Unlike previously reported peptide-based PPI inhibitors of BRCA1, the compounds identified could be directly administered to tumor cells, thus making them useful in targeting BRCA1/PARP-related pathways involved in DNA damage and repair response, for cancer therapy.作者: JAMB 時(shí)間: 2025-3-29 02:52
Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays,his approach is useful for screening a broad variety of structurally and functionally diverse RNAs. Here, we present a general method for the preparation and use of SMMs to rapidly identify small molecules that selectively bind to an RNA of interest.作者: 同時(shí)發(fā)生 時(shí)間: 2025-3-29 04:50 作者: Amylase 時(shí)間: 2025-3-29 10:13 作者: 平息 時(shí)間: 2025-3-29 15:25 作者: 相符 時(shí)間: 2025-3-29 17:20 作者: 煩躁的女人 時(shí)間: 2025-3-29 21:35
https://doi.org/10.1007/978-1-4939-6584-7Microarray fabrication; Imaging modes; small molecules; label-free approaches; imaging microarrays; bona 作者: MAZE 時(shí)間: 2025-3-30 02:12 作者: Servile 時(shí)間: 2025-3-30 04:10
Der Friedhof an der Schneeküste im Sternbild des Oriongstagen, lange bevor die Grabsteine durch die Str?ucher verdeckt werden, tauchen die Krokusse aus den schmelzenden Schneefl?chen auf. Ich ging hin, um sie aufblühen zu sehen, und so nahm ich auch an den Beerdigungen teil. Der Gegensatz zwischen den Ereignissen faszinierte mich. Auf der einen Seite v作者: 極大的痛苦 時(shí)間: 2025-3-30 09:06
Graph Dichotomy Algorithm and Its Applications to Analysis of Stocks Market that some of them can be different and some of them can coincide. The normalized entropy of this set is a reasonable index for formal definition of complexity of a given graph. This property allows us making every day short-term predictions of big crises at stock markets.作者: Substitution 時(shí)間: 2025-3-30 15:13
PT-Symmetry and Non-Hermitian Wave Transport in Microwaves and RF Circuits, – often stretching the borders of investigation to the most general area of non-Hermitian wave transport where concepts like coherent perfect absorbers, gain-induced lasing shut-down, and asymmetric transport are naturally emerging.作者: Ascendancy 時(shí)間: 2025-3-30 20:33
Conference proceedings 2019g Enterprise Engineering a reality...The 9 full papers and 3 short papers presented in this volume were carefully reviewed and selected from 24 submissions. They were organized in topical sections named: on architecture; on security and blockchain; on DEMO; and on teaching. ?.作者: arrogant 時(shí)間: 2025-3-30 20:59
Rudolf Bussertnt business processes out of a large data base. Not anymore single ratios, rather expressions in several dimensions are goals of benchmarking. On a basis of 282 european companies, patterns of organizational structures, cost structures, product attributes, and client relationships of successful comp作者: Abnormal 時(shí)間: 2025-3-31 03:08
Alexandra Dorfer,Gudrun Salmhofer,Lisa Scheerschmerzen, HWS-Syndrom. Durch viele nützliche Hinweise zu Indikationen, Pharmakokinetik und Wirkmechanismen sowie konkrete Praxistipps ein wertvoller Begleiter im Klinikalltag. Darüberhinaus ist es die optimale Prüfungsvorbereitung zur Erlangung der Zusatzbezeichnung "Spezielle Schmerztherapie". .978-3-642-20024-3作者: Osmosis 時(shí)間: 2025-3-31 07:16 作者: 人類學(xué)家 時(shí)間: 2025-3-31 11:42 作者: JOT 時(shí)間: 2025-3-31 16:03
https://doi.org/10.1007/978-3-531-92281-2Empf?nger-Sender; Informationsaustausch; Kommunikation; PR; Wahrhaftigkeit; ?ffentlichkeitsarbeit作者: 熱心 時(shí)間: 2025-3-31 19:36
Systems of Linear Equations, Matrices,n Deutschland bis vor kurzem noch ein v?llig unterbelichtetes Forschungsgebiet mit nur wenigen Pionierarbeiten war. Zu zeigen, welche Arbeiten in den vergangenen Jahren stattgefunden haben und welche Erkenntnisse dabei zutage gef?rdert wurden, ist das Ziel dieses Sammelbandes.978-3-658-11722-1978-3-658-11723-8作者: subordinate 時(shí)間: 2025-3-31 23:56
