標(biāo)題: Titlebook: Single-Cell Mutation Monitoring Systems; Methodologies and Ap Aftab A. Ansari,Frederick J. Serres Book 1984 Plenum Press, New York 1984 Fix [打印本頁(yè)] 作者: cobble 時(shí)間: 2025-3-21 19:54
書目名稱Single-Cell Mutation Monitoring Systems影響因子(影響力)
作者: conduct 時(shí)間: 2025-3-21 22:29
Book 1984ould then be evaluated with more complex tests, including those based on mammalian cells in culture. Testing in the final tier requires whole-animal studies, and is expensive and time-consum- ing, and even the results from these studies need to be extrapolated for human risk assessment. The mutation作者: 偽造 時(shí)間: 2025-3-22 02:40 作者: 雄偉 時(shí)間: 2025-3-22 06:37 作者: 漫不經(jīng)心 時(shí)間: 2025-3-22 08:53
James W. Allen,Karen Brock,James Campbell,Yousuf Sharief作者: oxidant 時(shí)間: 2025-3-22 14:24 作者: 抵制 時(shí)間: 2025-3-22 19:40
William L. Bigbee,Elbert W. Branscombntribute to hemorrhage, while interaction with complement resistance mediators may contribute to survival in serum. While not a classical intracellular pathogen, the interaction of leptospires and phagocytic cells appears complex, with bacteria surviving uptake and promoting apoptosis; mutants relat作者: 大火 時(shí)間: 2025-3-23 00:00
Masroor A. Baig,Aftab A. Ansarips on troubleshooting and avoiding known pitfalls..Cutting-edge and comprehensive, .Leptospira spp.: Methods and Protocols. is a valuable resource for researchers interested in learning more about this developing field and these fascinating organisms.??.作者: Arthr- 時(shí)間: 2025-3-23 05:17 作者: 傀儡 時(shí)間: 2025-3-23 08:01 作者: 大溝 時(shí)間: 2025-3-23 12:05 作者: bronchodilator 時(shí)間: 2025-3-23 15:07 作者: 徹底檢查 時(shí)間: 2025-3-23 20:00
Unscheduled DNA Synthesis as an Indicator of Genotoxic Exposure,revealed by autoradiography when UV irradiation was shown to induce the uptake of labeled thymidine into non-S-phase cells.. At least three steps are required: adduct formation; excision of the adducts; and DNA-strand polymerization and ligation (Figure 1)..作者: guzzle 時(shí)間: 2025-3-23 23:42 作者: LUMEN 時(shí)間: 2025-3-24 02:33 作者: Acclaim 時(shí)間: 2025-3-24 08:52
Masroor A. Baig,Aftab A. Ansarif leptospirosis. The chapters in this book cover topics such as the procedure to cultivate and isolate leptospires from both clinical and environmental samples; using methods like whole genome sequencing and Matrix Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry to identify bac作者: antiandrogen 時(shí)間: 2025-3-24 12:26
Use of Fluorescence-Activated Cell Sorter for Screening Mutant Cells,normal somatic cells that generally have little or no replicative capacity. As a result, a number of efforts are underway to develop nonclonogenic mutation assays applicable to cells obtained from . tissue samples and to find alternative means for authenticating the mutant pedigree of detected cells.作者: 倒轉(zhuǎn) 時(shí)間: 2025-3-24 15:45 作者: 慎重 時(shí)間: 2025-3-24 20:05 作者: OATH 時(shí)間: 2025-3-25 02:59
Somatic-Cell Mutation Monitoring System Based on Human Hemoglobin Mutants,y abnormal globin chains. Development of appropriate methods of screening blood samples should then permit detection and enumeration of red cells that contain an abnormal hemoglobin as a result of somatic mutation in a stem cell.作者: 果核 時(shí)間: 2025-3-25 06:19
Detection of Chemically Induced Y-Chromosomal Nondisjunction in Human Spermatozoa, presumably the number of investigators evaluating this technique are minimal. In this chapter, we will describe the studies that led to the development of this method, discuss the technique, and present data obtained using this procedure.作者: 含水層 時(shí)間: 2025-3-25 08:16
Book 1984 injury requires monitoring the exposed individuals for genetic damage and identifying chemicals that may cause mutation or cancer. Tests available for identifying mutagens or carcinogens range from relatively simple, rapid assays in prokaryotes and test systems utilizing mammalian cells in tissue c作者: TAIN 時(shí)間: 2025-3-25 14:34 作者: 創(chuàng)新 時(shí)間: 2025-3-25 19:49
The Identification of Somatic Mutations in Immunoglobulin Expression and Structure,time of animal cells has made it more difficult to establish useful genetic systems, the very complexity of such cells demands that molecular genetics be used if we are ever to fully understand how they function.作者: Thyroid-Gland 時(shí)間: 2025-3-25 23:50
Somatic-Cell Mutation Monitoring System Based on Human Hemoglobin Mutants,ozygous for an abnormal hemoglobin. It is assumed, first, that mutations arise spontaneously in human hemopoietic stem cells, as they do in gametal stem cells, and second, that somatic mutations of globin-chain genes do not diminish the viability of affected stem cells. The latter assumption is a re作者: ASSET 時(shí)間: 2025-3-26 00:50 作者: laparoscopy 時(shí)間: 2025-3-26 05:01
Development of a Plaque Assay for the Detection of Red Blood Cells Carrying Abnormal or Mutant Hemoen) has been recently reviewed.. The use of immunological methods for detection of mutations has been possible by using antibodies that can specifically recognize the amino acid difference(s) between the molecule normally present in a given cell and its variant form. Techniques like immunofluorescen作者: 嬉耍 時(shí)間: 2025-3-26 11:10 作者: acrophobia 時(shí)間: 2025-3-26 13:59
Application of Antibodies to 5-Bromodeoxyuridine for the Detection of Cells of Rare Genotype, The primary purpose of automating mutagen detection is to increase the speed and statistical reliability that is afforded by the instrumentation being recruited to this task, flow or image cytometry. In addition, this approach would eliminate the human bias and error characteristic of manual method作者: 致命 時(shí)間: 2025-3-26 16:57
Cytogenetic Abnormalities as an Indicator of Mutagenic Exposure,t to cycle. In animals there are several cell types that fit these criteria, but for humans there are to all intents and purposes only two types that are practically suitable. These are the bone marrow cells, which are a cycling population, and peripheral lymphocytes, which are normally noncycling, 作者: 違反 時(shí)間: 2025-3-26 22:32
Sister Chromatid Exchange Analysis in Lymphocytes,Although the fundamental nature of SCE is not well understood, interests in its frequency have been central both to historical and current studies. Early autoradiographic techniques used to detect this phenomenon were applied for a variety of investigations into its spontaneous and irradiationrelate作者: 清洗 時(shí)間: 2025-3-27 02:29
Unscheduled DNA Synthesis as an Indicator of Genotoxic Exposure,revealed by autoradiography when UV irradiation was shown to induce the uptake of labeled thymidine into non-S-phase cells.. At least three steps are required: adduct formation; excision of the adducts; and DNA-strand polymerization and ligation (Figure 1)..作者: outrage 時(shí)間: 2025-3-27 07:57
The Micronucleus Test as an Indicator of Mutagenic Exposure,and comprehensive assay systems for the detection of genotoxic effects. Such effects can be classified in three broad categories, namely (1) gene and point mutations, (2) chromosome mutations, and (3) genome mutations. It is well known that in humans these effects may lead to severe clinical disorde作者: BRACE 時(shí)間: 2025-3-27 11:41
The Identification of Somatic Mutations in Immunoglobulin Expression and Structure,egulation of gene expression and have been used to define the biosynthetic pathways of macromolecules. Mutants in both bacterial and animal viruses have made it possible to define their interactions with host cells and to identify and map the functions that they perform. Naturally occurring mutation作者: Excitotoxin 時(shí)間: 2025-3-27 14:46
Detection of Chemically Induced Y-Chromosomal Nondisjunction in Human Spermatozoa,s questionable or the genetic basis for the tests has yet to be established. Conversely, there are certain procedures where the potential for identifying genetic lesions in relevant systems is considerable, but their utilization is slow to develop. A procedure with great potential for identifying mu作者: triptans 時(shí)間: 2025-3-27 20:54
Application of Antibodies to 5-Bromodeoxyuridine for the Detection of Cells of Rare Genotype,g recruited to this task, flow or image cytometry. In addition, this approach would eliminate the human bias and error characteristic of manual methods. In the case of . assessment of mutagenesis, a method would be available to measure genetic variation in cells that either do not clone or clone at extremely low efficiencies.作者: 天氣 時(shí)間: 2025-3-27 22:39
ch genetic injury requires monitoring the exposed individuals for genetic damage and identifying chemicals that may cause mutation or cancer. Tests available for identifying mutagens or carcinogens range from relatively simple, rapid assays in prokaryotes and test systems utilizing mammalian cells i作者: Bernstein-test 時(shí)間: 2025-3-28 02:24
,Bildung — Motor oder Hemmnis für nachhaltige Entwicklung?,nen in einer Flut von Publikationen und Datenbanken: In den letzten fünf Jahren hat sich dementsprechend die Zahl der wissenschaftlichen Zeitschriftentitel um 26 Prozent auf rund 147 000 erh?ht. Im gleichen Zeitraum stieg die Zahl der Fachdatenbanken um 30 Prozent auf ungef?hr 8800. Weltweit erschei作者: EVICT 時(shí)間: 2025-3-28 10:10
The Red Eyease. It is important that every practising doctor has an understanding of the differential diagnosis of this common sign, and a categorisation of the signs, symptoms and management of the red eye will now be made from the standpoint of the non-specialist general practitioner.作者: AVOW 時(shí)間: 2025-3-28 10:28 作者: Glucocorticoids 時(shí)間: 2025-3-28 14:42 作者: coagulate 時(shí)間: 2025-3-28 22:46
Heinrich-Otto Bujachange individuals after a given number of generations. The experimental results show improvements in both computing time and quality of EEG classification with features extracted by multiresolution analysis (MRA), an approach widely used in the BCI field with useful properties for both temporal and作者: heckle 時(shí)間: 2025-3-29 02:50 作者: Postulate 時(shí)間: 2025-3-29 03:56 作者: 誘導(dǎo) 時(shí)間: 2025-3-29 10:53 作者: Instrumental 時(shí)間: 2025-3-29 15:28 作者: indignant 時(shí)間: 2025-3-29 17:48
Lecture Notes in Mechanical Engineering則 (precautionary principle) 以及合作原則等法律原則進(jìn)行了詳細(xì)分析。隨后, 本文重點(diǎn)關(guān)注當(dāng)代最重要的環(huán)境原則, 即可持續(xù)發(fā)展原則, 介紹了該原則的由來(lái)及主要構(gòu)成要素, 然后詳細(xì)分析了引用最多的國(guó)際條約以及國(guó)際法庭和法院的一些裁決, 這些裁決均對(duì)可持續(xù)發(fā)展原則給予了足夠的重視。.本文最后詳細(xì)敘述了環(huán)境法原則在國(guó)際環(huán)境法中可能發(fā)揮的各種作用, 目的是明確環(huán)境法原則對(duì)環(huán)境管理的實(shí)際及潛在影響。作者: 慢慢流出 時(shí)間: 2025-3-29 20:32
Nonlinear hyperbolic problems,tably their ability to generate discontinuous solutions also in the case of continuous initial and boundary data. The numerical approximation of these problems is far from easy. Here we will simply limit ourselves to point out how finite difference and finite element schemes can be applied in the case of one-dimensional equations.
