標題: Titlebook: Rational Drug Design; Methods and Protocol Thomas Mavromoustakos,Tahsin F. Kellici Book 2018 Springer Science+Business Media, LLC, part of [打印本頁] 作者: mentor 時間: 2025-3-21 18:01
書目名稱Rational Drug Design影響因子(影響力)
書目名稱Rational Drug Design影響因子(影響力)學科排名
書目名稱Rational Drug Design網(wǎng)絡公開度
書目名稱Rational Drug Design網(wǎng)絡公開度學科排名
書目名稱Rational Drug Design被引頻次
書目名稱Rational Drug Design被引頻次學科排名
書目名稱Rational Drug Design年度引用
書目名稱Rational Drug Design年度引用學科排名
書目名稱Rational Drug Design讀者反饋
書目名稱Rational Drug Design讀者反饋學科排名
作者: 嬉耍 時間: 2025-3-22 00:06
Panagiotis Lagarias,Youness Elkhou,Jayson Vedad,Athina Konstantinidi,Adam A. Profit,Tahsin F. Kellicaft darstellte. Eng damit verbunden war die Aussage von der Verdoppelung des Strombrauchs alle zehn Jahre. Seit einigen Jahren ist das in den entwickelten Industriel?ndern ganz anders: der Energieverbrauch w?chst langsamer als die Wirtschaft oder stagniert sogar. ?Strom und Konjunktur entkoppelt“, s作者: Foreknowledge 時間: 2025-3-22 01:30
Haralambos Tzoupis,Theodore Tselios der Einspeisung von Biogas in Erdgasnetze. Das Buch bietet einen soliden und umfassenden überblick nach dem Stand der Technik und informiert über Trends und neuere Entwicklungen. Es ist den Herausgebern gelungen, unter Mitarbeit einer Vielzahl kompetenter Fachleute ein solides Werk "aus einem Guss"作者: 碳水化合物 時間: 2025-3-22 05:48
Jeffrey R. Brender,Janarthanan Krishnamoorthy,Anirban Ghosh,Anirban Bhunia(d. h. Bio?l- und Holzkohleerzeugung). Zus?tzlich wird auf die thermo-chemische Umwandlung in hydrothermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten作者: 瘙癢 時間: 2025-3-22 10:33 作者: TAG 時間: 2025-3-22 14:39
Andrew Anighoro,Jürgen Bajorath(d. h. Bio?l- und Holzkohleerzeugung). Zus?tzlich wird auf die thermo-chemische Umwandlung in hydrothermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten作者: MOTIF 時間: 2025-3-22 20:56
Patricia Saenz-Méndez,Leif A. Eriksson(d. h. Bio?l- und Holzkohleerzeugung). Zus?tzlich wird auf die thermo-chemische Umwandlung in hydrothermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten作者: Pathogen 時間: 2025-3-23 01:08
Vassilios Myrianthopoulos,George Lambrinidis,Emmanuel Mikros(d. h. Bio?l- und Holzkohleerzeugung). Zus?tzlich wird auf die thermo-chemische Umwandlung in hydrothermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten作者: 隱藏 時間: 2025-3-23 03:12
Davide Sabbadin,Veronica Salmaso,Mattia Sturlese,Stefano Moro(d. h. Bio?l- und Holzkohleerzeugung). Zus?tzlich wird auf die thermo-chemische Umwandlung in hydrothermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten作者: 文件夾 時間: 2025-3-23 07:46
1064-3745 and cutting-edge, .Rational Drug Design: Methods and Protocols. .aims to ensure successful results in the further study of this vital field..978-1-4939-9347-5978-1-4939-8630-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 訓誡 時間: 2025-3-23 13:09
Adam A. Profit,Ruel Z. B. Desameroüberblick nach dem Stand der Technik und informiert über Trends und neuere Entwicklungen. Es ist den Herausgebern gelungen, unter Mitarbeit einer Vielzahl kompetenter Fachleute ein solides Werk "aus einem Guss"978-3-662-07025-3作者: Mundane 時間: 2025-3-23 14:56
Flavio Ballantehermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten978-3-662-47438-9作者: REIGN 時間: 2025-3-23 21:17 作者: Creditee 時間: 2025-3-23 23:23
Dimitra-Danai Varsou,Spyridon Nikolakopoulos,Andreas Tsoumanis,Georgia Melagraki,Antreas Afantitishermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten978-3-662-47438-9作者: 謊言 時間: 2025-3-24 04:02
David A. Sykes,Steven J. Charltonhermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten978-3-662-47438-9作者: BOGUS 時間: 2025-3-24 07:47 作者: MANIA 時間: 2025-3-24 13:36 作者: 有助于 時間: 2025-3-24 18:31
Simone Schierle,Daniel Merkhermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten978-3-662-47438-9作者: conjunctivitis 時間: 2025-3-24 23:04 作者: 倔強一點 時間: 2025-3-24 23:14
Konstantinos D. Marousis,Aikaterini C. Tsika,Maria Birkou,
Minos-Timotheos Matsoukas,Georgios A. Spyhermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten978-3-662-47438-9作者: ADOPT 時間: 2025-3-25 05:45
Ugo Perricone,Marcus Wieder,Thomas Seidel,Thierry Langer,Alessandro Padovahermaler Atmosph?re (z.?B. hydrothermale Karbonisierung) eingegangen..·?????? Die?.physikalisch-chemische Umwandlung.?beinhaltet die Pflanzen?lerzeugung und die entsprechenden Umwandlungsm?glichkeiten978-3-662-47438-9作者: 食草 時間: 2025-3-25 09:03
Book 2018by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Authoritative and cutting-edge, .Rational Drug Design: Methods and Protocols. .aims to ensure successful results in the further study of this vital field..作者: 遭受 時間: 2025-3-25 14:41
,Molecular Dynamics Simulations on the Bioactive Molecule of hIAPP22–29 (NFGAILSS) and Rational Drug that led to an “amyloidogenic core” observed from NOE experiments. The results showed that in DMSO and HFIP environment, Phe is not in spatial proximity with Leu or Ile, and this is consistent with an amyloidogenic core. However, in an amphipathic environment such as the model lipid bilayers, this 作者: cauda-equina 時間: 2025-3-25 18:44 作者: DAUNT 時間: 2025-3-25 22:38 作者: DAFT 時間: 2025-3-26 01:25
Enalos+ KNIME Nodes: New Cheminformatics Tools for Drug Discovery,nderline the value and the effectiveness of the nodes for molecular descriptors calculation and QSAR predictive model development. In addition, case studies are also presented demonstrating the benefits of the use of Enalos+ nodes for database exploitation within a drug discovery project.作者: 軟弱 時間: 2025-3-26 08:03
In Silico Screening of Compound Libraries Using a Consensus of Orthogonal Methodologies,tocol can be performed in its basic version as described in this work, but it can also be extended manually by integrating a number of different screening tools and their case-specific variations to further increase the performance of virtual screening in prioritizing the most promising compounds fo作者: Hyperopia 時間: 2025-3-26 10:32
The Use of Dynamic Pharmacophore in Computer-Aided Hit Discovery: A Case Study,the binding pocket and then evaluate the most important interactions that are created during the host-guest recognition process. Findings derived from the MD analysis, especially focused on interactions, can be in fact exploited as features for pharmacophore generation or constraints to be used in t作者: 減至最低 時間: 2025-3-26 13:24 作者: 仇恨 時間: 2025-3-26 19:26 作者: BRIDE 時間: 2025-3-26 23:04 作者: Tortuous 時間: 2025-3-27 03:56 作者: Mets552 時間: 2025-3-27 07:02
Thomas Mavromoustakos,Tahsin F. KelliciIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key note and implementation advice from the expert作者: Constant 時間: 2025-3-27 10:48
978-1-4939-9347-5Springer Science+Business Media, LLC, part of Springer Nature 2018作者: finale 時間: 2025-3-27 15:40
Rational Drug Design978-1-4939-8630-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Prostaglandins 時間: 2025-3-27 18:45
1064-3745 tion advice from the expert.This volume covers several aspects of rational drug design, such as synthesis of novel bioactive drugs; development and application of new methodologies; computational methods valuable for the establishment of new approaches in drug discovery; and the effects of physical-作者: Cocker 時間: 2025-3-27 23:54
A Hybrid Virtual Screening Protocol Based on Binding Mode Similarity,based on the assessment of binding mode similarity between docked compounds and a bound reference ligand. In this context, both experimental and computationally modeled poses have been successfully used as references for three-dimensional (3D) similarity calculations. In this chapter, the methods applied in recent validation studies are described.作者: 有其法作用 時間: 2025-3-28 04:24 作者: 極微小 時間: 2025-3-28 06:37 作者: 確定方向 時間: 2025-3-28 13:34
,Molecular Dynamics Simulations on the Bioactive Molecule of hIAPP22–29 (NFGAILSS) and Rational Drugerived using X-ray and its 2D NOESY NMR experiments in ..-DMSO and .-HFIP solvents. This molecule contains eight of the ten amino acids of the 20–29 region of the human islet amyloid polypeptide (hIAPP) often referred as the “amyloidogenic core.” Amyloid deposits are well-known to cause as many as 2作者: meditation 時間: 2025-3-28 18:38
Development of Peptide-Based Inhibitors of Amylin Aggregation Employing Aromatic and Electrostatic sfolds to form amyloid plaques in the pancreas. The self-assembly of hIAPP has been linked to the loss of insulin production and β-cell death. Recent investigations have revealed that soluble oligomers of hIAPP are the cytotoxic species responsible for β-cell death and not insoluble amyloid fibrils.作者: absolve 時間: 2025-3-28 22:22
In Silico Drug Design: Non-peptide Mimetics for the Immunotherapy of Multiple Sclerosis,ng, molecular docking, and molecular dynamics (MD) simulations have been extensively applied, separately or in combination, in the design of potent molecules. The techniques involve the identification of a potential drug target (e.g., protein) and its subsequent characterization. The next step in th作者: 領導權 時間: 2025-3-28 23:16 作者: Pepsin 時間: 2025-3-29 04:51 作者: Outspoken 時間: 2025-3-29 07:19 作者: 擺動 時間: 2025-3-29 12:17 作者: LIMN 時間: 2025-3-29 18:01 作者: notion 時間: 2025-3-29 20:39 作者: Misnomer 時間: 2025-3-29 23:58 作者: 讓空氣進入 時間: 2025-3-30 06:54 作者: Arbitrary 時間: 2025-3-30 11:53 作者: 令人發(fā)膩 時間: 2025-3-30 15:11
Exploring Polypharmacology in Drug Design,ly describes the mechanism of biomolecular recognition. The need to take into account the polypharmacology in structure-based drug design has led to the development of several computational tools. Here we present a computational protocol to identify promising compounds against several biological tar作者: 混沌 時間: 2025-3-30 19:38 作者: evasive 時間: 2025-3-30 21:00 作者: Pcos971 時間: 2025-3-31 03:11 作者: 有雜色 時間: 2025-3-31 05:14 作者: 發(fā)現(xiàn) 時間: 2025-3-31 13:03
Lead Identification Through the Synergistic Action of Biomolecular NMR and In Silico Methodologies,computational methodologies to screen large databases readily available for testing small molecules, in synergy with NMR techniques focused on protein–ligand interactions, can be used in the early lead compound identification process against a protein drug target.作者: 無瑕疵 時間: 2025-3-31 15:28 作者: 言外之意 時間: 2025-3-31 21:07
Development of Peptide-Based Inhibitors of Amylin Aggregation Employing Aromatic and Electrostatic ctronic effects or electrostatic charge repulsion. These peptide-based modulators may serve as lead compounds for the development of more drug-like molecules and demonstrate that tuning π-electron density and employing charged amyloid disrupting elements are viable approaches toward the design of potential amyloid inhibitors.作者: 真 時間: 2025-4-1 01:14
Protein-Ligand Docking in Drug Design: Performance Assessment and Binding-Pose Selection,ing software, a comparative docking assessment in an early research stage represents a must-use step to minimize fails in molecular modeling. This chapter describes how to perform a docking assessment, using freely available tools, in a semiautomated fashion.作者: 制度 時間: 2025-4-1 03:49 作者: 無能力之人 時間: 2025-4-1 06:35
Dynamic Undocking: A Novel Method for Structure-Based Drug Discovery,us making it exceptionally useful in virtual screening. Here, we present a protocol suitable for DUck’s application in drug design strategy, as well as notes that will help to solve common problems addressed by users.
