作者: 招惹 時(shí)間: 2025-3-21 22:29
https://doi.org/10.1007/978-3-662-09127-2Antidiabetics; Biguanides; Diabetes; Diabetes mellitus; Glucosidase inhibitors; Insulin; Non-Pharmacologic作者: 有斑點(diǎn) 時(shí)間: 2025-3-22 03:55 作者: 災(zāi)禍 時(shí)間: 2025-3-22 04:52 作者: 救護(hù)車 時(shí)間: 2025-3-22 10:18
Springer-Verlag Berlin Heidelberg 1996作者: 災(zāi)禍 時(shí)間: 2025-3-22 14:26 作者: Immobilize 時(shí)間: 2025-3-22 17:27
Chemistry and Structure-Activity Relationships of BiguanidesIn 1878–1879, . obtained a new compound in very low yield via a condensation reaction of thiourea and phosphorus trichloride (which are cyanamide generators) with guanidine.作者: 緯線 時(shí)間: 2025-3-23 00:53
Non-Pharmacological Management of Non-Insulin-Dependent Diabetesood lipids and will thereby reduce the risk for coronary heart disease. Even in insulin-dependent diabetes mellitus (IDDM), the role of diet is not only to help minimize the short-term fluctuations of blood glucose but also to reduce the risk of long-term complications by helping to achieve optimum 作者: 哺乳動(dòng)物 時(shí)間: 2025-3-23 04:51 作者: 賞心悅目 時(shí)間: 2025-3-23 06:07 作者: 讓步 時(shí)間: 2025-3-23 12:28 作者: Keratin 時(shí)間: 2025-3-23 15:53 作者: 侵蝕 時(shí)間: 2025-3-23 18:22 作者: 評(píng)論性 時(shí)間: 2025-3-23 22:29
Introductionountries and commonly between ethnic groups in the same country. Currently diabetes affects an estimate 15.1 million people in North America, 12.6 million in Latin America, 18.5 million in Europe, 6.6 million in the former USSR, 5.3 million in Africa, 51.4 million in Asia, and just under 1 million i作者: Genetics 時(shí)間: 2025-3-24 03:54
Pathophysiology of Type 2 Diabetes Mellitus population of most Western countries, with, however, wide international variation (. et al. 1993). Furthermore, NIDDM is often undiagnosed even in the Western countries (. et al. 1990), and numerous data indicate that undiagnosed NIDDM is not a benign condition (Harris 1993). Certainly, NIDDM is a 作者: 語源學(xué) 時(shí)間: 2025-3-24 08:04
Non-Pharmacological Management of Non-Insulin-Dependent DiabetesM). Today’s diet, which is rich in fats and relatively low in carbohydrates and fibres, the so-called westernized diet, is highly associated with the occurrence of NIDDM. It is therefore concluded that dietary modifications are the mainstay of treatment for NIDDM. These modifications, concentrating 作者: 輕信 時(shí)間: 2025-3-24 13:53 作者: genesis 時(shí)間: 2025-3-24 15:47 作者: Atheroma 時(shí)間: 2025-3-24 20:40 作者: reaching 時(shí)間: 2025-3-25 02:50 作者: champaign 時(shí)間: 2025-3-25 04:13 作者: 爆炸 時(shí)間: 2025-3-25 08:54 作者: 多節(jié) 時(shí)間: 2025-3-25 14:48 作者: mortuary 時(shí)間: 2025-3-25 18:34 作者: Ligneous 時(shí)間: 2025-3-25 22:06
Toxicology of Biguanidese, phenylethylbiguanide (phenformin), was given marketing approval in the United States in 1957. Due to the serious side effects, however, the compound was withdrawn from the market in the United States and the major European countries about 20 years later. Similar problems occurred with .-butylbigu作者: 開頭 時(shí)間: 2025-3-26 00:20
Clinical Pharmacology of Biguanides983; . 1992). Repeated reports of phenformin-associated lactic acidosis led to the withdrawal of this biguanide in the United States in 1977 and in most other countries. Buformin shared the same fate, but metformin escaped withdrawal, even if the use became more restricted. At the same time the Univ作者: ARY 時(shí)間: 2025-3-26 05:35 作者: 受人支配 時(shí)間: 2025-3-26 08:27 作者: overhaul 時(shí)間: 2025-3-26 16:04 作者: 遭遇 時(shí)間: 2025-3-26 20:09 作者: 流眼淚 時(shí)間: 2025-3-26 21:47
Sulfonylureas: Physico-chemical Properties, Analytical Methods of Determination and Bioavailabilitytic drugs include acetohexamide, acetylcarbutamide, carboxytolbutamide, carbutamide, chlorpropamide, glibenclamide, glibornuride, gliclazide, glimepiride, glipizide, gliquidone, glisoxepide, metahexamide, tolazamide and tolbutamide. The structural formulas of some of the important antidiabetic agents are given in Fig. 1.作者: 暫時(shí)休息 時(shí)間: 2025-3-27 02:48 作者: 令人悲傷 時(shí)間: 2025-3-27 06:09
Clinical Pharmacology of Sulfonylureasion of insulin secretion. Sulfonylureas bind to receptor-like structures on the B cell, which may be closely linked to or be part of the potassium channels (. et al. 1987; . et al. 1988; . et al. 1990). The binding capacity of different sulfonylureas reflects their ability to stimulate insulin secretion.作者: 令人心醉 時(shí)間: 2025-3-27 13:26 作者: Immobilize 時(shí)間: 2025-3-27 15:33 作者: 策略 時(shí)間: 2025-3-27 18:21
Chemistry and Structure-Activity Relationships of Glucosidase Inhibitorse rational design of a lead compound, when the biochemical mechanism and the structure of the enzyme are well known. In the late 1960s, when we started to look for such potent and selective inhibitors, we had to choose the random screening approach, relying mainly on testing of extracts of the culture broths of microorganisms.作者: 完整 時(shí)間: 2025-3-28 00:55
0171-2004 -threatening disease. This attitude needs to be changed because the complications asso- ciated with the adult form of diabetes affect almost every organ system. The high morbidity and mortality of non-insulin-dependent diabetes mellitus (NIDDM) suggest that current treatment strategies are unsatisfa作者: menopause 時(shí)間: 2025-3-28 03:16 作者: Mawkish 時(shí)間: 2025-3-28 06:27 作者: 乞丐 時(shí)間: 2025-3-28 13:06 作者: Tdd526 時(shí)間: 2025-3-28 14:42
d Syndrome addresses the complete range of conditions produced by this common disorder which is also known as APS or "sticky blood" syndrome. APS is one of the main causes of strokes (40%), leg deep vein thrombosis, and recurrent miscarriages in women. It is an important risk factor for thrombosis i作者: 換話題 時(shí)間: 2025-3-28 21:13
Eljar Akhgarnush individual alveolar ventilation (.A) and blood flow (.). The resultant PO. of the end-capillary blood leaving each of these lung units (PeCO.) depends on the inspired PO., the PO. of the mixed venous blood (P.O.), the ability of the blood and gas phases to equilibrate and the ventilation-perfusion 作者: 2否定 時(shí)間: 2025-3-29 02:17 作者: NOMAD 時(shí)間: 2025-3-29 03:33
AI-Empowered Blockchain Techniques Against Cybersecurity Context in IoT: A Surveyf Things (IoT) solutions have been created over the past 20?years by small, medium-sized, and major businesses to improve our quality of life. The need for more robust cybersecurity safeguards is becoming more critical as technology develops. Despite the fact that they are both different in nature a作者: Aerate 時(shí)間: 2025-3-29 08:00 作者: 獨(dú)行者 時(shí)間: 2025-3-29 12:50 作者: 嚴(yán)厲譴責(zé) 時(shí)間: 2025-3-29 17:32
Lycopene for the Prevention and Treatment of Prostate Disease,which commonly improve symptoms but are often off-set by adverse events including erectile dysfunction, which affect quality of life. Similarly, a variety of treatment options exist for the treatment of prostate cancer. The applicability of these prostate cancer treatments is reliant on stage of dis作者: 富饒 時(shí)間: 2025-3-29 20:04 作者: Occlusion 時(shí)間: 2025-3-30 02:47 作者: 掙扎 時(shí)間: 2025-3-30 05:16
Traversing Middleboxes with the Host Identity Protocolsociations are established solely between the communicating end hosts, HIP also aims to interwork with middleboxes such as NATs and firewalls. This paper investigates this interworking aspect and proposes a solution for secure middlebox traversal.作者: 使長(zhǎng)胖 時(shí)間: 2025-3-30 09:52
The Education System of the Cayman Islands,nd curriculum. It also discusses key events and issues in the development of the education system, the overall administration and organization of the sector, the supply of teachers from overseas, and the structure within the International Standard Classification of Education (ISCED).作者: 類似思想 時(shí)間: 2025-3-30 13:38 作者: Restenosis 時(shí)間: 2025-3-30 17:08
Oswald Georg Bauerntgen ist nach wie vor die wichtigste, aussagekr?ftigste und h?ufigste radiologische Untersuchung auf einer Intensivstation; man rechnet mit 1,5 Thoraxr?ntgen pro Intensivbett und Tag [36]. An die Bildqualit?t einer Thoraxbettaufnahme sind deshalb ?hnliche Forderungen zu stellen wie bei Aufnahmen am作者: 圍裙 時(shí)間: 2025-3-30 20:46
Analysis of , Germline Small RNA Pathways,O binding partner. Here, we describe a framework for analyzing AGO/sRNA pathways in the germline, from using CRISPR-Cas9 to tag or mutate AGOs, through protocols for the extraction, sequencing, and analysis of sRNAs from AGO IPs and . mutants.作者: 進(jìn)取心 時(shí)間: 2025-3-31 04:01
Obligations as Social Constructsfirms andhow they successfully manage their M&A.?The author brings to this work his 14 years of experience in Japan and has relied not only on English literature but also on original Japanese sources in creatin978-4-431-56401-0978-4-431-54989-5作者: 2否定 時(shí)間: 2025-3-31 07:10
Sarah L. Bergaes PET-CT as a true combined modality.Chapters are written b.This book is specifically designed to meet the needs of practicing radiologists. Chapters are written by radiologists who appreciate and understand both PET and CT. The emphasis on an integrated understanding of PET-CT as a combined modali作者: 譏諷 時(shí)間: 2025-3-31 10:14
Ius Gentium: Comparative Perspectives on Law and Justicehttp://image.papertrans.cn/u/image/940204.jpg作者: 西瓜 時(shí)間: 2025-3-31 15:25
ocedures have been added to the original "Tension-free hernioplasty", described by Irving Lichtenstein at thebeginning of the ‘70s, but widespread only at the end of the ‘80s. Some of these prosthetic techniques had a remarkable diffusion all over the world, while others were adopted only in certain countries978-2-287-59766-4978-2-8178-0853-6
