標(biāo)題: Titlebook: Oncogene-Directed Therapies; Janusz Rak Book 2003 Springer Science+Business Media New York 2003 angiogenesis.cell.gene therapy.metastasis. [打印本頁(yè)] 作者: 離開浮于空中 時(shí)間: 2025-3-21 19:19
書目名稱Oncogene-Directed Therapies影響因子(影響力)
作者: 豎琴 時(shí)間: 2025-3-21 20:54
The Molecular Basis of Chromosomal Instability in Human Cancer Cellskpoint genes that affect their ability to direct the appropriate segregation of chromosomes in cell division. Future work is aimed at the identification of the genes involved in these processes that are altered in human cancers.作者: aneurysm 時(shí)間: 2025-3-22 04:25
Oncogenic Receptor Tyrosine Kinases This plethora of surface and cytoplasmic events culminates in the regulation of gene transcription, eventually leading to alterations in cellular behavior ranging from entry into the cell cycle to terminal differentiation (for a specific example of the pleiotropic response to a growth factor see re作者: Aphorism 時(shí)間: 2025-3-22 07:24 作者: armistice 時(shí)間: 2025-3-22 09:11 作者: 賞錢 時(shí)間: 2025-3-22 15:25
Oncogenes as Therapeutic Targets to Prevent Metastasis of metastasis affected by Ras suggest that the ability of cancer cells to grow in a secondary site can be significantly affected by activated Ras-signaling. Because oncogene expression can markedly influence the growth phase of the metastatic process, inhibition of oncogene action offers a clinical作者: 有特色 時(shí)間: 2025-3-22 18:55 作者: 使閉塞 時(shí)間: 2025-3-23 00:12 作者: IDEAS 時(shí)間: 2025-3-23 04:50
Clinical Evaluation of Agents Targeting Epidermal Growth Factor Receptor (EGFR) in Cancertosis, and inhibition of tumor invasion and metastasis .. Furthermore, overexpression of EGFR, frequently observed in a number of human cancers, is associated with poor overall prognosis, increased tumor recurrence, and decreased patient survival .. The hypothesis that EGFR might be a cancer therape作者: transplantation 時(shí)間: 2025-3-23 06:50 作者: 天空 時(shí)間: 2025-3-23 10:37
Kirill Rosen PhD,Jorge Filmus PhDricks.A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastro978-88-470-3976-6978-88-470-3977-3Series ISSN 2280-9848 Series E-ISSN 2281-0854 作者: travail 時(shí)間: 2025-3-23 17:52
Janusz Rak MD PhD,Robert S. Kerbel PhDricks.A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastro978-88-470-3976-6978-88-470-3977-3Series ISSN 2280-9848 Series E-ISSN 2281-0854 作者: BROTH 時(shí)間: 2025-3-23 21:33
Ann F. Chambers PhD,Hemanth J. Varghese BScricks.A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastro978-88-470-3976-6978-88-470-3977-3Series ISSN 2280-9848 Series E-ISSN 2281-0854 作者: Medley 時(shí)間: 2025-3-23 22:17
ricks.A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastro978-88-470-3976-6978-88-470-3977-3Series ISSN 2280-9848 Series E-ISSN 2281-0854 作者: Incorruptible 時(shí)間: 2025-3-24 06:26 作者: 懲罰 時(shí)間: 2025-3-24 08:48
Edward H. Lin MD,James L. Abbruzzese MDricks.A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastro978-88-470-3976-6978-88-470-3977-3Series ISSN 2280-9848 Series E-ISSN 2281-0854 作者: 瑣碎 時(shí)間: 2025-3-24 11:26 作者: infantile 時(shí)間: 2025-3-24 16:58 作者: 夾死提手勢(shì) 時(shí)間: 2025-3-24 19:01
2196-9906 targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.978-1-4684-9738-0978-1-59259-313-2Series ISSN 2196-9906 Series E-ISSN 2196-9914 作者: Infirm 時(shí)間: 2025-3-25 00:31
therefore to get clinicians closer to these pathologies, describing their complexity and the current state of the art in diagnostic, therapeutic and pathological classification strategy, thus providing them with the tools for a modern and updated clinical management of these patients.作者: Adrenaline 時(shí)間: 2025-3-25 06:46
Susan J. Done MA, MB, BCHIR, PhD, FRCPC,Jeremy A. Squire PhD therefore to get clinicians closer to these pathologies, describing their complexity and the current state of the art in diagnostic, therapeutic and pathological classification strategy, thus providing them with the tools for a modern and updated clinical management of these patients.作者: engrave 時(shí)間: 2025-3-25 11:03
Eric C. Holland MD, PhD at different levels of government is not controlled. The failures recorded in the history of . in countries such as Italy, which should focus its development policies on this extraordinary and strategic resource, are a warning we should not ignore: from the sharing of guidelines, programs, and mast作者: 細(xì)胞學(xué) 時(shí)間: 2025-3-25 14:53 作者: 滔滔不絕地講 時(shí)間: 2025-3-25 19:06
the formation of the IPAA (ileal pouch-anal anastomosis), together with helpful tips and tricks.A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastro作者: sultry 時(shí)間: 2025-3-25 22:46 作者: 狗窩 時(shí)間: 2025-3-26 01:15
Senji Shirasawa MD, PhD,Takehiko Sasazuki MD, PhDthe formation of the IPAA (ileal pouch-anal anastomosis), together with helpful tips and tricks.A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastro作者: Little 時(shí)間: 2025-3-26 05:00 作者: CANON 時(shí)間: 2025-3-26 09:38
Genetic Basis of Cancer Progressionetic alterations. This model was first postulated by Cavenee et al. . and further developed by Fearon and Vogelstein .. In the simplest situation of a hematologic neoplasm, such as chronic myeloid leukemia (CML), neoplasia arises as a direct result of the formation of the Philadelphia chromosome .. 作者: 服從 時(shí)間: 2025-3-26 12:47
The Molecular Basis of Chromosomal Instability in Human Cancer Cellsenotype of human cancer has been well described throughout the long history of careful microscopic and karyotypic scrutiny of human tumors .,.. More recently, this tradition has been complemented by molecular and cellular analyses of tumor cell aneuploidy. These analyses have shown that tumor cell a作者: medium 時(shí)間: 2025-3-26 18:07 作者: VEIL 時(shí)間: 2025-3-26 22:47
Oncogenic Receptor Tyrosine Kinaseshormones, which penetrate through the plasma membrane due to their hydrophobic character, these factors must bind a cell surface-localized receptor. In contrast to multispan receptors for neuropeptides and chemical transmitters, growth factor receptors transverse the plasma membrane only once, and t作者: Minatory 時(shí)間: 2025-3-27 03:57
Ras-Mediated Deregulation of Gene Expression and Contribution to Oncogenesis stimulation of a wide spectrum of cell surface receptors, converge on and activate Ras .. Activated Ras, in turn, interacts with a multitude of downstream effector targets to initiate functionally diverse cytoplasmic signaling pathways .. Many of the cytoplasmic signaling components that function u作者: Abrupt 時(shí)間: 2025-3-27 09:10 作者: insolence 時(shí)間: 2025-3-27 13:19
Genetic Basis of Altered Responsiveness of Cancer Cells to Their Microenvironment can provide a selective pressure for the expansion of populations of oncogenically transformed rodent cells with reduced apoptotic sensitivity, not only to hypoxia ., but to chemotherapeutic agents as well ..作者: 吹牛需要藝術(shù) 時(shí)間: 2025-3-27 16:49 作者: Mawkish 時(shí)間: 2025-3-27 19:56 作者: CUR 時(shí)間: 2025-3-28 00:14
Oncogenes and Tumor Angiogenesismulus for studies on oncogenes .. Although this approach proved to be very powerful in establishing the genetic causes of cancer, it was in itself insufficient to properly interpret the resulting complexity of the unfolding pathological process .. Indeed, cancer as a disease involves a multitude of 作者: Arrhythmia 時(shí)間: 2025-3-28 03:35 作者: 磨坊 時(shí)間: 2025-3-28 10:20
The Impact of Oncogenes on Tumor Maintenancee number, chromosomal translocation, and gene amplifications .. These alterations result in a gain of function of oncogenes and a loss of function of tumor suppressor genes, leading to uncontrolled growth, differentiation, and apoptosis. The number of mutations required for a tumor to develop in hum作者: Perigee 時(shí)間: 2025-3-28 12:06
Primary and Secondary Events in Oncogene-Driven Tumor Development mouse models of tumor development offer the means to reproducibly isolate different stages of tumor progression, which then are amenable to pathological, genetic, and biochemical analyses. Moreover, tumor cell lines derived from the different tumor stages are useful tools in experimentally addressi作者: Parley 時(shí)間: 2025-3-28 15:50
Targeting Oncogenes in Hematopoietic Malignancieslogy of leukemia was poorly understood. While cytotoxic chemotherapeutic drugs have played, and continue to play, an essential role in cancer management, their relative lack of specificity and the frequency of resistance have been a limit to this approach. This has prompted a search for targeted the作者: Verify 時(shí)間: 2025-3-28 22:21
Clinical Evaluation of Agents Targeting Epidermal Growth Factor Receptor (EGFR) in Cancerrises from a multistep process promoted by the imbalanced growth signals as a consequence of gain of oncogene and/or loss of tumor suppressor genes .. The six essential cancer hallmarks include persistent cell growth signals, insensitivity to antigrowth signals, evasion of apoptosis, persistent angi作者: champaign 時(shí)間: 2025-3-29 02:10
Inhibition of the HER-2/neu Oncogenembers include the epidermal growth factor receptor (EGFR), HER-3, and HER-4 .. The HER-2/neu receptor protein is expressed in a wide variety of tissues, including the breast, ovary, endometrium, lung, liver, gastrointestinal tract, kidney, and central nervous system, and HER-2/neu is believed to pla作者: 心胸狹窄 時(shí)間: 2025-3-29 04:32 作者: 人類 時(shí)間: 2025-3-29 09:44
ons in the pancreatic gland of asymptomatic patients, and in the last decades a more detailed and specific pathological classification definitivelyopened an unexpected world of more or less rare pancreatic tumors. As a matter of fact, nowadays most surgical procedures deal with these so called uncom作者: 流利圓滑 時(shí)間: 2025-3-29 12:43
Susan J. Done MA, MB, BCHIR, PhD, FRCPC,Jeremy A. Squire PhDons in the pancreatic gland of asymptomatic patients, and in the last decades a more detailed and specific pathological classification definitivelyopened an unexpected world of more or less rare pancreatic tumors. As a matter of fact, nowadays most surgical procedures deal with these so called uncom作者: 真實(shí)的人 時(shí)間: 2025-3-29 15:55 作者: 大門在匯總 時(shí)間: 2025-3-29 22:49 作者: lesion 時(shí)間: 2025-3-30 02:05
cordingly, it starts with the symptoms and the clinical picture, before addressing the use of radiological and endoscopic studies that are performed to make a diagnosis, and the role of the pathological examination. The book also includes detailed information on the medical treatment of the disease,作者: 不連貫 時(shí)間: 2025-3-30 06:17 作者: 休閑 時(shí)間: 2025-3-30 08:31
Kirill Rosen PhD,Jorge Filmus PhDuate type of medications to use.Explains surgical techniquesThis book reviews the latest advances in treating ulcerative colitis. Its structure is designed to reflect the natural presentation of the disease; accordingly, it starts with the symptoms and the clinical picture, before addressing the use作者: flavonoids 時(shí)間: 2025-3-30 13:06
Janusz Rak MD PhD,Robert S. Kerbel PhDuate type of medications to use.Explains surgical techniquesThis book reviews the latest advances in treating ulcerative colitis. Its structure is designed to reflect the natural presentation of the disease; accordingly, it starts with the symptoms and the clinical picture, before addressing the use作者: parsimony 時(shí)間: 2025-3-30 19:47 作者: 怕失去錢 時(shí)間: 2025-3-30 22:03 作者: 大猩猩 時(shí)間: 2025-3-31 02:46 作者: 織布機(jī) 時(shí)間: 2025-3-31 08:43
uate type of medications to use.Explains surgical techniquesThis book reviews the latest advances in treating ulcerative colitis. Its structure is designed to reflect the natural presentation of the disease; accordingly, it starts with the symptoms and the clinical picture, before addressing the use作者: Altitude 時(shí)間: 2025-3-31 10:48 作者: HEPA-filter 時(shí)間: 2025-3-31 14:07
Edward H. Lin MD,James L. Abbruzzese MDuate type of medications to use.Explains surgical techniquesThis book reviews the latest advances in treating ulcerative colitis. Its structure is designed to reflect the natural presentation of the disease; accordingly, it starts with the symptoms and the clinical picture, before addressing the use
