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標(biāo)題: Titlebook: Nuclear Receptors: From Structure to the Clinic; Iain J. McEwan,Raj Kumar Book 2015 Springer International Publishing Switzerland 2015 NMR [打印本頁]

作者: retort    時間: 2025-3-21 17:07
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作者: 預(yù)示    時間: 2025-3-22 08:23
Structural Analysis of Heterodimeric Nuclear Receptorsing domains. They explain how DNA dictates the topology of the complex and its asymmetry, thus remodeling the interaction surfaces according to the different response elements. The structural investigations provide additional information related to the dynamics of the regulation process like the sol
作者: 落葉劑    時間: 2025-3-22 09:59
Primate-Specific Multi-Functional Androgen Receptor Coregulator and Proto-Oncogene Melanoma Antigen- cancer-testis antigen expressed on the human X chromosome. MAGE-A11 binding to the AR F.LF motif competes with the AR N/C interaction and increases AR transcriptional activity by stabilizing AR dimer-dimer interactions and recruiting p300 and p160 nuclear receptor coactivators. MAGE-A11 increases t
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Book 20155 years ago, which heralded in the idea of a superfamily of intracellular receptor proteins that bound small molecule ligands: classical steroid hormones, vitamins, fatty acids and other products of metabolism. These signals are then transmitted through multiprotein receptor-DNA complexes, leading t
作者: 貨物    時間: 2025-3-23 06:57
Christopher J. Millard,John W. R. Schwabencestors did so long ago—look up and appreciate the stars. His insights in this revised book spread farther and wider than ever before in this learned and enchanting tour of the skies..978-3-319-37101-6978-3-319-19878-1Series ISSN 0067-0057 Series E-ISSN 2214-7985
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ken into account. Stability can be restored, however, if the Dirac operator with the field, instead of the bare Dirac operator, is used to define an electron. Thus, the notion of a “bare” electron without its self-field is physically questionable.978-3-540-27056-0
作者: 新娘    時間: 2025-3-23 16:30
Iain J. McEwan,Raj Kumarken into account. Stability can be restored, however, if the Dirac operator with the field, instead of the bare Dirac operator, is used to define an electron. Thus, the notion of a “bare” electron without its self-field is physically questionable.978-3-540-27056-0
作者: gusher    時間: 2025-3-23 19:25
ken into account. Stability can be restored, however, if the Dirac operator with the field, instead of the bare Dirac operator, is used to define an electron. Thus, the notion of a “bare” electron without its self-field is physically questionable.978-3-540-27056-0
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Jordan T. White,Hesam N. Motlagh,Jing Li,E. Brad Thompson,Vincent J. Hilserken into account. Stability can be restored, however, if the Dirac operator with the field, instead of the bare Dirac operator, is used to define an electron. Thus, the notion of a “bare” electron without its self-field is physically questionable.978-3-540-27056-0
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Marek Or?owski,Piotr Dobryszycki,Anna Zoglowek,Joanna Pieprzyk,Katarzyna Bielska,Beata Greb-Markiewi
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Iain J. McEwan,Raj Kumarn mathematical physics, particularly for his contribution toThis fourth edition of selecta of my work on the stability of matter contains recent work on two topics that continue to fascinate me: Quantum electrodynamics (QED) and the Bose gas. Three papers have been added to Part VII on QED. As I men
作者: 使殘廢    時間: 2025-3-26 00:31
n mathematical physics, particularly for his contribution toThis fourth edition of selecta of my work on the stability of matter contains recent work on two topics that continue to fascinate me: Quantum electrodynamics (QED) and the Bose gas. Three papers have been added to Part VII on QED. As I men
作者: Interferons    時間: 2025-3-26 05:40
Peter J. Fuller,Jun Yang,Morag J. Youngn mathematical physics, particularly for his contribution toThis fourth edition of selecta of my work on the stability of matter contains recent work on two topics that continue to fascinate me: Quantum electrodynamics (QED) and the Bose gas. Three papers have been added to Part VII on QED. As I men
作者: Cervical-Spine    時間: 2025-3-26 11:08
Raj Kumar,Iain J. McEwann mathematical physics, particularly for his contribution toThis fourth edition of selecta of my work on the stability of matter contains recent work on two topics that continue to fascinate me: Quantum electrodynamics (QED) and the Bose gas. Three papers have been added to Part VII on QED. As I men
作者: Intercept    時間: 2025-3-26 15:44
Vanessa Dubois,Christine Helsen,Liesbeth Clinckemalie,Lien Spans,Micha?l Laurent,Leen Antonio,Thomasn mathematical physics, particularly for his contribution toThis fourth edition of selecta of my work on the stability of matter contains recent work on two topics that continue to fascinate me: Quantum electrodynamics (QED) and the Bose gas. Three papers have been added to Part VII on QED. As I men
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Christopher J. Millard,John W. R. Schwabeork of Alfred Lord Tennyson and Gerald Manley Hopkins.Offers.In this updated second edition renowned amateur comet-searcher David H. Levy?expands on his work about the?intricate relationship between the night sky and the works of English Literature.?This revised and expanded text includes new sectio
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Twenty-five Years of Nuclear Receptor Structure Analysis: From the Laboratory to the Clinic,ematic representation of nuclear receptors, based on biochemical studies, to crystal and NMR structures of the isolated ligand binding and DNA binding domains, which have increased our understanding of receptor structure and provided fresh insights into function. Recent progress has seen the emergen
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作者: Vital-Signs    時間: 2025-3-27 09:29
Glucocorticoid Receptor Structure and Function the level of gene regulation by binding to the glucocorticoid receptor (GR). The phenomenon of hormone-dependent activation of the GR has extensively been exploited for the clinical evolution of small molecule selective glucocorticoid receptor modulators. Current understanding of the available stru
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作者: 淡紫色花    時間: 2025-3-27 22:53
Structural Analyses of Ordered and Disordered Regions in Ecdysteroid Receptoreptor (EcR) and Ultraspiracle (Usp). Upon dimerization EcR and Usp recognize the ecdysteroid response elements (EcREs) present in promoter regions of the ecdsysteroid-responsive genes. Detailed structural analyses of EcR and Usp DNA binding domains revealed that each protein contributes in different
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作者: Custodian    時間: 2025-3-28 08:20
Primate-Specific Multi-Functional Androgen Receptor Coregulator and Proto-Oncogene Melanoma Antigen-stosterone or dihydrotestosterone. AR transcriptional activity is modulated by the androgen-dependent NH.- and carboxyl-terminal (N/C) interaction between the AR NH.-terminal F.LF motif and the activation function 2 surface of the ligand binding domain. The N/C interaction stabilizes AR and modulate
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作者: 密碼    時間: 2025-3-29 00:00
Twenty-five Years of Nuclear Receptor Structure Analysis: From the Laboratory to the Clinic,uctural analysis are paralleled by the growing evidence linking nuclear receptor function to normal physiological processes and disease. The insights gained from nuclear receptor structures have the potential to be translated into new drugs for major diseases, including cancer, metabolic syndrome and cardiovascular disease.
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