作者: 友好關系 時間: 2025-3-21 23:39
Clinical Instruments to Evaluate and Guide Treatment in Schizophrenia,ces. This has led to the use of functional capacity measures which monitor an individual’s ability to perform functionally meaningful tasks even if they do not complete these tasks. Attention has also focused on interview-based measures of cognition and negative symptoms. Both of these psychopatholo作者: Hdl348 時間: 2025-3-22 02:30 作者: DIKE 時間: 2025-3-22 07:54 作者: fidelity 時間: 2025-3-22 10:03
Towards Medication-Enhancement of Cognitive Interventions in Schizophrenia, might be possible to significantly enhance the efficacy of cognitive therapies. We review and suggest several laboratory measures that might detect potential pro-neurocognitive effects of drugs in individual patients, using a “test dose” design, aided by specific biomarkers predicting an individual作者: Comprise 時間: 2025-3-22 14:27
Mutant Mouse Models in Evaluating Novel Approaches to Antipsychotic Treatment,enetics of schizophrenia and mutant models relating to replicable risk genes. Lastly, we extend this discussion by exemplifying two new variant approaches in mutant mice that may serve as prototypes for advancing antipsychotic drug development. There is continuing need not only to address numerous t作者: 類似思想 時間: 2025-3-22 17:42 作者: 節(jié)約 時間: 2025-3-22 22:48
The Role of Dopamine D3 Receptors in Antipsychotic Activity and Cognitive Functions,iating positive symptoms is still unsettled, selective D. receptor antagonism has therapeutic features for schizophrenia and beyond as demonstrated by several animal models: improved cognitive function, emotional processing, executive function, flexibility, and social behavior. D. receptor antagonis作者: Ornithologist 時間: 2025-3-23 03:18 作者: collagenase 時間: 2025-3-23 08:09 作者: 火光在搖曳 時間: 2025-3-23 12:24
Glutamatergic Synaptic Dysregulation in Schizophrenia: Therapeutic Implications,eptor function whose allelic variants are associated with increased risk for schizophrenia including genes encoding .-amino acid oxidase, its modulator G72, dysbindin, and neuregulin. The parvalbumin-positive, fast-firing GABAergic interneurons that provide recurrent inhibition to cortical-limbic py作者: Folklore 時間: 2025-3-23 14:37
Nicotinic Receptors and Functional Regulation of GABA Cell Microcircuitry in Bipolar Disorder and Ss at this locus. Using laser microdissection, recent studies have focused selectively on these two layers and their associated GABA cells using microarray technology. The results have provided support for the idea that nicotinic cholinergic receptors play a particularly important role in regulating 作者: 拒絕 時間: 2025-3-23 21:19 作者: Ige326 時間: 2025-3-23 23:20 作者: PRE 時間: 2025-3-24 05:43 作者: 正論 時間: 2025-3-24 07:07 作者: 廣大 時間: 2025-3-24 12:04
Jared W. Young,Nurith Amitai,Mark A. Geyer is sufficiently smooth, then such heuristic can attain a regret which is arbitrarily close to square root. For the Bayesian approach, a Thompson sampling-based heuristic can achieve square root regret.作者: BARK 時間: 2025-3-24 16:31
Colm M. P. O’Tuathaigh,Lieve Desbonnet,John L. Waddington is sufficiently smooth, then such heuristic can attain a regret which is arbitrarily close to square root. For the Bayesian approach, a Thompson sampling-based heuristic can achieve square root regret.作者: 文字 時間: 2025-3-24 20:35 作者: Priapism 時間: 2025-3-25 02:22 作者: 繁榮地區(qū) 時間: 2025-3-25 03:22 作者: FIS 時間: 2025-3-25 09:15 作者: integral 時間: 2025-3-25 15:17 作者: 鉗子 時間: 2025-3-25 19:14 作者: 口訣 時間: 2025-3-25 22:52
Anton Bespalov,Corinna Klein,Berthold Behl,Gerhard Gross,Hans Schoemakersis and basic experience with functions of a complex variable, which most first-year graduate students in mathematics, engineering, or other formal sciences have already acquired. Measure theory and integration theory are necessary only for the last section of the final chapter..978-0-8176-4998-2作者: Modify 時間: 2025-3-26 02:43 作者: LVAD360 時間: 2025-3-26 08:09
Gerhard Gross,Karla Drescherls. This text cohesively links key and related KO material and provides a deeper understanding of the domain in its broadest sense and with enough detail to truly investigate its many fa978-3-319-36264-9978-3-319-09357-4作者: animated 時間: 2025-3-26 10:11
Hsun-Hua Chou,Elizabeth Twamley,Neal R. Swerdlowal for bias in estimation and existence of closed-form test distributions or asymptotic theory. We illustrate some promising modifications to bandit procedures to address power and bias issues, and we reflect upon the open challenges that remain for an increased uptake of bandit models in clinical trials.作者: Silent-Ischemia 時間: 2025-3-26 16:33 作者: 噴出 時間: 2025-3-26 19:37
Cognitive Impairment in Schizophrenia,lities in occupational, social, and economic functioning in patients with schizophrenia and an important treatment target. The profile of deficits in schizophrenia includes many of the most important aspects of human cognition: attention, memory, reasoning, and processing speed. While various effort作者: 結束 時間: 2025-3-27 00:25 作者: –DOX 時間: 2025-3-27 01:33
Towards Medication-Enhancement of Cognitive Interventions in Schizophrenia,riable neuropathology of schizophrenia strongly suggests that it is not currently, and may never be, correctable with drugs. In contrast, several forms of cognitive therapy have been demonstrated to have modest but lasting positive effects on cognition, symptoms, and functional outcomes in schizophr作者: 隱士 時間: 2025-3-27 08:33
Mutant Mouse Models in Evaluating Novel Approaches to Antipsychotic Treatment, they relate to behavioral, psychopharmacological, and cellular phenotypes of putative import for antipsychotic drug development. Mutant models appear to be heuristic at two main levels; firstly, by indicating the functional roles of neuronal components thought to be of relevance to the putative pat作者: BURSA 時間: 2025-3-27 13:24
5-HT2C Agonists as Therapeutics for the Treatment of Schizophrenia,iple signal transduction pathways leading to engagement of a number of intracellular signaling molecules. Moreover, there are multiple allelic variants of the 5-HT. receptor and the receptor is subject to RNA editing in the coding regions. The complexity of this receptor is further emphasized by the作者: 猛擊 時間: 2025-3-27 17:22 作者: Mri485 時間: 2025-3-27 21:31 作者: chemoprevention 時間: 2025-3-28 01:35 作者: Hangar 時間: 2025-3-28 04:02
Glutamatergic Synaptic Dysregulation in Schizophrenia: Therapeutic Implications,mpliance with existing antipsychotic medications. An alternative hypothesis invoking the excitatory neurotransmitter, glutamate, arose out of clinical observations that NMDA receptor antagonists, the dissociative anesthetics like ketamine, can replicate in normal individuals the full range of sympto作者: 定點 時間: 2025-3-28 06:34 作者: patriarch 時間: 2025-3-28 14:19 作者: Amnesty 時間: 2025-3-28 14:41
Nicotinic Receptors and Functional Regulation of GABA Cell Microcircuitry in Bipolar Disorder and S interneurons. Significant decreases in the expression of GAD67, a marker for GABA cell function, have been found repeatedly in several different brain regions that include the hippocampus. In this region, nicotinic receptors are thought to play an important role in modulating the activity of GABAer作者: 賞錢 時間: 2025-3-28 22:49
Development of Disease-Modifying Treatment of Schizophrenia,interest rather than to produce preclinical effects similar to those of currently used antipsychotics. Application of such novel strategy will undoubtedly require a very deep understanding of the disease biology that is just starting to emerge. Alternatively, one may let environmental experiences of作者: gerontocracy 時間: 2025-3-29 01:32 作者: 導師 時間: 2025-3-29 06:32 作者: 先兆 時間: 2025-3-29 09:14
Richard S. E. Keefe,Philip D. Harveyrecent developments for the joint learning and pricing problem with inventory constraints using both frequentist and Bayesian approaches. As the total demand and supply in the system scales proportionally, information-theoretical lower bounds indicate that any algorithm must have a regret (i.e., the作者: 剛毅 時間: 2025-3-29 15:20 作者: 中世紀 時間: 2025-3-29 16:49
Hsun-Hua Chou,Elizabeth Twamley,Neal R. Swerdlowcs, machine learning, economics, and others. It is a framework well suited to model resource allocation under uncertainty in a wide variety of contexts. Across the existing theoretical literature, the use of bandit models to optimally design clinical trials is one of the most typical motivating appl作者: 美食家 時間: 2025-3-29 23:37 作者: 使服水土 時間: 2025-3-30 00:41
Sharon Rosenzweig-Lipson,Thomas A. Comery,Karen L. Marquis,Jonathan Gross,John Dunloprecent developments for the joint learning and pricing problem with inventory constraints using both frequentist and Bayesian approaches. As the total demand and supply in the system scales proportionally, information-theoretical lower bounds indicate that any algorithm must have a regret (i.e., the作者: Agronomy 時間: 2025-3-30 06:40 作者: Interregnum 時間: 2025-3-30 09:29 作者: 調情 時間: 2025-3-30 14:03 作者: CIS 時間: 2025-3-30 20:12 作者: Ceramic 時間: 2025-3-31 00:28
E. J. Herman,M. Bubser,P. J. Conn,C. K. Jonesinteresting counterexamples, that demonstrate the frontiers .This fully revised, updated, and corrected edition of?.The Elements of Operator Theory.?includes a significant expansion of?problems and solutions used to illustrate the principles of operator theory. Written in?a user-friendly, motivating
