標(biāo)題: Titlebook: Neuroscience in the 21st Century; From Basic to Clinic Donald W. Pfaff,Nora D. Volkow Reference work 20162nd edition Springer Science+Busin [打印本頁] 作者: 從未迷惑 時(shí)間: 2025-3-21 19:51
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作者: Little 時(shí)間: 2025-3-21 23:33
Axonal Transportional transport, known collectively as axonal transport, is not fundamentally different from the pathways of macromolecular and membrane traffic found in other parts of the neuron, or indeed in any eukaryotic cell, but it is unique for the volume and scale of the traffic required to maintain these long processes.作者: Contort 時(shí)間: 2025-3-22 00:33 作者: Jejune 時(shí)間: 2025-3-22 08:11 作者: happiness 時(shí)間: 2025-3-22 11:50
Voltage-Gated Ion Channelsxins tetrodotoxin, saxitoxin, and scorpion toxin (discussed later in this chapter). However, the molecular basis of excitability remained unclear until the 1980s, when Dr. William A. Catterall and his colleagues at the University of Washington discovered the VGSC protein (in 1980) and the VGCC prote作者: 我要沮喪 時(shí)間: 2025-3-22 14:42 作者: 違法事實(shí) 時(shí)間: 2025-3-22 20:15
Signal Transduction-Dependent Channelsmark.. Because of its large conductance, this voltage- and calcium-activated K. channel was christened “maxi-K” or “BK” (for big K.). This high single-channel conductance is not only a characteristic of Slo1 but is shared by the other members of this family of K. channels, Slo2 and Slo3. These chann作者: 教唆 時(shí)間: 2025-3-22 23:47 作者: 易發(fā)怒 時(shí)間: 2025-3-23 05:02 作者: 甜瓜 時(shí)間: 2025-3-23 08:26
Neural Stem Cells in Cerebral Cortex Developmentother mammals, including hominids. Key differences exist, however, and they are pinpointed where appropriate. We also highlight some areas of intense current research and mention ideas that could contribute to our understanding of CNS development and function.作者: Mangle 時(shí)間: 2025-3-23 13:07
Adult Neurogenesisrogenesis critically contributes to hippocampal function, allowing life-long adaptation processes. If adult neurogenesis fails, this might contribute to several important diseases, including dementias, major depression and schizophrenia, as well as temporal lobe epilepsy.作者: 哪有黃油 時(shí)間: 2025-3-23 16:31 作者: Inoperable 時(shí)間: 2025-3-23 19:14
Dendritic Elaboration: Morphology and Chemistry – involving the summation of signals as well as spatial – entailing the aggregation of excitatory and inhibitory inputs from individual branches. Dendrites were thought to convey electrical signals passively. However, as shown recently dendrites can activly support action potentials and release neu作者: 放縱 時(shí)間: 2025-3-24 01:27
Regressive Phenomena: Refining Connectionsy of the guidance cues that instructed neurons to their target initially also regulate regressive events later in development. Beyond the removal of supernumerary connections, regressive processes also allow for the creation of a number of complex synaptic structures and the refinement of individual作者: Conclave 時(shí)間: 2025-3-24 04:27
Dendritic Morphology and Functionl and electrical compartments and the implications for synaptic integration and plasticity will be reviewed. In addition, this chapter will review different forms of dendritic computation and its implication in synaptic plasticity and in the hierarchical processing of information in the cerebral cor作者: hysterectomy 時(shí)間: 2025-3-24 07:45
Cell Biology of the Synapse PSD displays a complex array of proteins, which are arranged in a hierarchical manner: (1) receptors, ion channels, and adhesion proteins shared with the postsynaptic membrane; (2) scaffold proteins connecting the receptors to each other, to other membrane components, and to the actin cytoskeleton;作者: 調(diào)整 時(shí)間: 2025-3-24 12:50 作者: Pedagogy 時(shí)間: 2025-3-24 18:15 作者: 激怒某人 時(shí)間: 2025-3-24 22:08 作者: Flatter 時(shí)間: 2025-3-25 02:11 作者: ureter 時(shí)間: 2025-3-25 07:14
Rolf Sprengel-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: 生來 時(shí)間: 2025-3-25 08:12 作者: 業(yè)余愛好者 時(shí)間: 2025-3-25 13:17
Stewart Hendry-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: Flavouring 時(shí)間: 2025-3-25 17:12 作者: 斷言 時(shí)間: 2025-3-25 22:40
Inna Tabansky,Joel N. H. Stern-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: ETCH 時(shí)間: 2025-3-26 04:02
Felipe Mora-Bermúdez,Miguel Turrero García,Wieland B. Huttner-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: Observe 時(shí)間: 2025-3-26 06:44 作者: Inexorable 時(shí)間: 2025-3-26 09:02
Peter Kozulin,Linda J. Richards-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: 抱怨 時(shí)間: 2025-3-26 13:18 作者: Expressly 時(shí)間: 2025-3-26 16:56
Will Agnew-Svoboda,Alex L. Kolodkin,Martin M. Riccomagno-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: 獨(dú)白 時(shí)間: 2025-3-26 23:04
-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: SCORE 時(shí)間: 2025-3-27 03:02 作者: Interferons 時(shí)間: 2025-3-27 06:02 作者: handle 時(shí)間: 2025-3-27 10:33
Rochelle S. Cohen-the-art applications in important technical areas, this thoroughly revised and updated edition is an excellent reference to a widespread academic, industrial, and professional engineering audience..978-0-387-30877-7Series ISSN 2522-8692 Series E-ISSN 2522-8706 作者: 惡名聲 時(shí)間: 2025-3-27 14:10 作者: Maximize 時(shí)間: 2025-3-27 19:11 作者: mediocrity 時(shí)間: 2025-3-28 00:07
as. ..Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding978-1-4939-3474-4作者: 不知疲倦 時(shí)間: 2025-3-28 05:04 作者: 駁船 時(shí)間: 2025-3-28 09:28
Voltage-Gated Ion Channels), Ca. (VGCC), and K. (VGPC) channels are responsible for action potential generation in electrically excitable cells, for example, neurons and muscle cells, and for regulation of membrane potential and intracellular Ca. levels in other cell types. The basic functional properties of this protein fam作者: ironic 時(shí)間: 2025-3-28 14:22 作者: Moderate 時(shí)間: 2025-3-28 16:32 作者: 猜忌 時(shí)間: 2025-3-28 20:16
Post-Synaptic Potentials and Action Potentials: Membrane Potentialsormation takes place at a neuron’s axon hillock and initial segment, and conduction of the integrated signal occurs down its axon. And at the hundreds of terminals formed by its axon, a neuron transmits information to its targets. This division of labor among the several parts of a neuron is referre作者: LEVER 時(shí)間: 2025-3-29 00:32 作者: 滔滔不絕地講 時(shí)間: 2025-3-29 05:45 作者: venous-leak 時(shí)間: 2025-3-29 09:54
Adult Neurogenesis Rodents and primates have two neurogenic zones, the hippocampus and the olfactory bulb. Lower vertebrates often have many more sites of adult neurogenesis. In the peripheral nervous system, there is high neurogenesis in the olfactory epithelium. Neurogenesis in the olfactory bulb originates from pr作者: Tractable 時(shí)間: 2025-3-29 14:08
Axonal Guidance: Making Connectionshese circuits during brain development, neurons extend an axon from the cell body to make connections with neurons in target brain areas, which can be a considerable distance away from the neuronal cell body. To ensure that axons accurately elongate toward the correct target field over such a distan作者: defibrillator 時(shí)間: 2025-3-29 18:14 作者: canonical 時(shí)間: 2025-3-29 23:44 作者: dendrites 時(shí)間: 2025-3-30 01:38 作者: nerve-sparing 時(shí)間: 2025-3-30 07:49
Axonal Transportnces, up to a meter or more in large animals. Remarkably, however, most axonal components originate in the nerve cell body, at one end of the axon, and must be shipped out along the axon by mechanisms of intracellular motility. In addition, signals from the axon and its environment must be conveyed 作者: Perennial長期的 時(shí)間: 2025-3-30 11:43 作者: 內(nèi)行 時(shí)間: 2025-3-30 16:03
Molecular Regulation of Synaptic Releaseinterspersed along terminal axonal branches or demarcate the end point of axonal arborization (nerve terminals). At these sites, the axonal lumen is enlarged, and the cytoplasmic space is filled with numerous small membrane vesicles, termed synaptic vesicles, that serve as storage organelles for neu作者: 必死 時(shí)間: 2025-3-30 19:16
The Postsynaptic Density not display perforations. The intimacy of its association with the postsynaptic membrane is reflective of the distribution of some proteins, which are shared between the PSD and postsynaptic membrane, e.g., receptors, ion channels, and adhesion proteins. The PSD displays a complex array of proteins作者: 腐敗 時(shí)間: 2025-3-30 22:17 作者: 橡子 時(shí)間: 2025-3-31 04:50 作者: commune 時(shí)間: 2025-3-31 06:31
