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標(biāo)題: Titlebook: Nephrotoxicity; In Vitro to In Vivo P. H. Bach,E. A. Lock Book 1989 Springer Science+Business Media New York 1989 development.etiology.eva [打印本頁(yè)]

作者: 桌前不可入    時(shí)間: 2025-3-21 18:06
書目名稱Nephrotoxicity影響因子(影響力)




書目名稱Nephrotoxicity影響因子(影響力)學(xué)科排名




書目名稱Nephrotoxicity網(wǎng)絡(luò)公開度




書目名稱Nephrotoxicity網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Nephrotoxicity被引頻次




書目名稱Nephrotoxicity被引頻次學(xué)科排名




書目名稱Nephrotoxicity年度引用




書目名稱Nephrotoxicity年度引用學(xué)科排名




書目名稱Nephrotoxicity讀者反饋




書目名稱Nephrotoxicity讀者反饋學(xué)科排名





作者: 歪曲道理    時(shí)間: 2025-3-21 22:31

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https://doi.org/10.1007/978-1-4757-2040-2development; etiology; evaluation; homeostasis; immunology; kidney; renal failure; safety; toxicity
作者: Condyle    時(shí)間: 2025-3-22 13:59

作者: SLAG    時(shí)間: 2025-3-22 18:23
Differential Effects of Cadmium and Mercury on Lysosomal Enzymes in the Kidney of Myxine GlutinosaIn man and most animals the exposure to the environmental pollutants cadmium and mercury results in accumulation of these heavy metals especially in the kidneys and the liver. At the cellular level proteinbound heavy metals are enriched in the lysosomal system after pinocytotic uptake.
作者: 改革運(yùn)動(dòng)    時(shí)間: 2025-3-22 23:05
Species Differences in Renal Structure and Function — Applications to Nephrotoxicity in Man (26). Marshall had shown that dog renal tubules accumulate the dye phenol red even when glomerular filtration was stopped by lowering the blood pressure. However, due to the belief held by most physiologists in the theory proposed by Cuhsny (that tubular secretion did not exist), the proofs present
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作者: Capture    時(shí)間: 2025-3-23 05:56
Predicting the Kidney Burden of Toxic Metalsposure, the resulting dose to the kidney and effects on kidney function. Development of methods for directly measuring or predicting kidney burden of metals in humans is a central component of this problem. Experiments in laboratory animals allow a rigorous exploration of the biokinetics of metals i
作者: CRASS    時(shí)間: 2025-3-23 11:27
A Prospective Study of Proteinuria in Cadmium Workersrliest biological sign of Cd interference with kidney function. Cadmium can decrease the tubular reabsorption of low molecular weight proteins (< 40, 000 dalton), such as ?2-m and RBP, and it can also enhance the glomerular filtration of high molecular weight proteins (> 40, 000 dalton), such as alb
作者: 注意力集中    時(shí)間: 2025-3-23 13:54
Red Blood Cell Negative Charges as an Index of the Glomerular Polyanion in Chronic Cadmium Poisoningcules such as albumin (1). Loss of glomerular polyanion in clinical or experimental renal diseases is associated with an enhanced excretion of anionic molecules. Evidence has been presented by recent studies (2, 3) that the negative charges of the red blood cells (RBCs) membrane, as determined by th
作者: FLEET    時(shí)間: 2025-3-23 20:34
Some Considerations on Critical Concentration of Cadmium for Renal Toxicity in Ratsarly in the liver and kidney and during the life-long exposure a renal Cd concentration becomes higher than a hepatic Cd concentration, which often causes renal tubular dysfunction (Friberg et al., 1985). Thus, we need to know the critical concentration of Cd to obtain information on the safety marg
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Nephrotoxicity of Cadmium in Chickensmarawickrama, 1979; Webb, 1979). There are various common features such as bone demineralisation, hypercalcaemia, anaemia, hypertension, and accumulation of Cd. in the liver, then in other tissue, predominantly the kidney. Among the consequences of Cd. nephrotoxicity are various cellular and biochem
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Protective Effect of Low Concentrations of Mercury Against HgCl2-Induced Nephrotoxicitylular distribution or excretion of mercury. Six main overlapping classes of compounds have been used to protect against mercury nephrotoxicity, these including beta-blocking agents, diuretics, chelators, substances that induce metallothioneins, agents involving a competition with mercury for the sam
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作者: Campaign    時(shí)間: 2025-3-25 00:59
Analysis of Unscheduled Dna Synthesis and S-Phase Synthesis in F344 Rat Kidney After in Vivo Treatmeess the issue of tissue-specificity. Tests that focus on tissuespecific responses such as the in vivo — in vitro unscheduled DNA synthesis (UDS) and S-phase synthesis (SPS) assays (Mirsalis, et al., 1985; Mirsalis, 1987) have been reasonably successful in the prediction of hepatocarcinogenic potenti
作者: 縮影    時(shí)間: 2025-3-25 04:47
In Vitro and in Vivo HgCl2-Induced Nephrotoxicity Assessed by Tubular Enzymes Releaseic parameters and electrolytes excretion. However, the acute tubular necrosis involved in many forms of toxic nephropathy is frequently detected and quantified by the evaluation of the urinary activity of marker enzymes form various segments of the nephron. Enzymuria has been shown to be an early an
作者: 使饑餓    時(shí)間: 2025-3-25 07:39
Prevention and Reversal of Mercuric Chloride-Induced Increases in Renal Vascular Resistance by Captosed rat kidney (IPRK) allows changes in RVR to be monitored precisely following nephrotoxin exposure. Mercuric chloride causes dose-dependent increases in RVR in filtering perfused rat kidneys (1) . We have examined the prevention and/or reversibility of these alterations in RVR by hydralazine, vera
作者: KIN    時(shí)間: 2025-3-25 14:44
Regioselective Acute Tubular Necrosis in Renal Cortical Slices Following HgCl2 and K2Cr2O7: Localizavely, has been reproduced in renal cortical slices (Ruegg et al, 1987a). This demonstrates that the toxicity of these two metals results from the innate sensitivity of these segments of the nephron to the specific metal and is not a result of altered blood flow or feed-back mechanisms . The question
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作者: 搜尋    時(shí)間: 2025-3-25 23:31
Early Indicators of Lead Nephropathy1) . Changes in serum creatinine and blood urea nitrogen (BUN) have proved to be relatively insensitive indices of renal impairment in individual workers, although epidemiological studies in large numbers of workers have indicated a statistically significant increase in both parameters with length o
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Bodil Schmidt-Nielsenry systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body‘s cells. Because physiological conduits have deformable and reactive walls, mac
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R. A. Goyer,C. R. Weinberg,W. M. Victery,C. R. Millerry systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body‘s cells. Because physiological conduits have deformable and reactive walls, mac
作者: GRE    時(shí)間: 2025-3-26 14:17
Gary L. Diamond,Thomas W. Clarkson,John B. Hursh,M. George Cherianry systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body‘s cells. Because physiological conduits have deformable and reactive walls, mac
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Z. H. Endre,L. G. Nicholls,P. J. Ratcliffe,J. G. G. Ledinghamh with practical clinical applications.Presents a consistent.Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology.? The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracel
作者: 瘋狂    時(shí)間: 2025-3-26 22:09
C. E. Ruegg,A. J. Gandolfi,A. K. Brendelh with practical clinical applications.Presents a consistent.Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology.? The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracel
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F. Khalil-Manesh,H. C. Gonick,E. Weiler,V. Rosen,L. Roche,A. Mutti,E. Bergamaschi,R. Alinovi,I. Franh with practical clinical applications.Presents a consistent.Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology.? The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracel
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作者: fixed-joint    時(shí)間: 2025-3-27 17:08
Cadmium May Predispose Mice to Immune Complex-Mediated Renal Injury: Another Possible Mechanism for antigen antibody complexes in the circulation which in turn might lead to greater deposition of the complexes in the glomeruli of the kidney and possibly other sites potentially injurious to organ function.
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In Vitro and in Vivo HgCl2-Induced Nephrotoxicity Assessed by Tubular Enzymes Releaseuantified by the evaluation of the urinary activity of marker enzymes form various segments of the nephron. Enzymuria has been shown to be an early and are much a more sensitive index of tubular damage than haemodynamic or electrolyte changes (Price, 1982).
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作者: 一美元    時(shí)間: 2025-3-29 07:05
Predicting the Kidney Burden of Toxic Metalsnless they can be validated with quantitative assessments in humans. Methods for in vivo measurement or estimation of metals in kidney can be used to test models that are based on laboratory animal data, and thus, potentially, can lead to a greatly improved understanding of exposure-effect relationships for nephrotoxic metals in humans.
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作者: 檢查    時(shí)間: 2025-3-29 12:48
Nephrotoxicity of Cadmium in Chickensidney it can pass through the glommruli and be reabsorbed. At a certain total level of the metal, some Cd. will not be bound in metallothionein and can therefore exert a toxic effect (Piscator, 1986) .
作者: 我的巨大    時(shí)間: 2025-3-29 16:12
Protective Effect of Low Concentrations of Mercury Against HgCl2-Induced NephrotoxicityCd, etc (Yoshikawa, 1970). Against this background, the present work was undertaken to determine whether a pretreatment with low concentrations of mercury, the so-called “Mercurius corrosivus” also protects against lethal doses of HgCl..
作者: Intercept    時(shí)間: 2025-3-29 22:10
agent, only a few clinical end-effects are diagnosed. Thus nephropathies are generally classified as acute or chronic renal failure, malignancies or immunological changes. The weaknesses in diagnosing nephropathies arises because of the effective role the kidney plays in maintaining homeostasis, des
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Book 1989ngency of chemical safety evaluation for their potential nephrotoxic effects. This is strongly countered by the increased financial pressure to identify potentially nephrotoxic chemicals earlier in their development and humanitarian considerations to more closely relate animal test to the clinical s
作者: A簡(jiǎn)潔的    時(shí)間: 2025-3-30 14:03
e the stringency of chemical safety evaluation for their potential nephrotoxic effects. This is strongly countered by the increased financial pressure to identify potentially nephrotoxic chemicals earlier in their development and humanitarian considerations to more closely relate animal test to the clinical s978-1-4757-2042-6978-1-4757-2040-2
作者: receptors    時(shí)間: 2025-3-30 19:59
Z. H. Endre,L. G. Nicholls,P. J. Ratcliffe,J. G. G. Ledinghamimprove cardiac function, and discussion of future directions.? Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology.? It is an invaluable reference for cardiology researchers and practitioners..978-1-4899-9576-6978-1-4419-9461-5
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H. J. Mason,L. J. Somervaille,D. R. Tennant,D. R. Chettle,M. C. Scottimprove cardiac function, and discussion of future directions.? Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology.? It is an invaluable reference for cardiology researchers and practitioners..978-1-4899-9576-6978-1-4419-9461-5
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Chiharu Tohyama,Naoko Sugihira,Kazuo T. Suzuki,Masataka Murakami,Hiroshi Saito
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