標(biāo)題: Titlebook: NMR: Principles and Applications to Biomedical Research; Jay W. Pettegrew Book 1990 Springer-Verlag New York Inc. 1990 Optische Koh?renzto [打印本頁(yè)] 作者: DIGN 時(shí)間: 2025-3-21 18:33
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作者: 移動(dòng) 時(shí)間: 2025-3-21 21:48
T. C. Farraring) what is the molecular basis; (d) considering the universal ribosome conservation, what is the capability of functional plasticity and cellular adaptation of the ribosome biogenesis pathway?.In this review, we provide a brief overview of ribosome biogenesis across the tree of life and try to ill作者: Meander 時(shí)間: 2025-3-22 03:35 作者: dendrites 時(shí)間: 2025-3-22 08:21 作者: 性滿(mǎn)足 時(shí)間: 2025-3-22 11:15
B. S. Duncan,J. F. Brinkley,R. B. Altman,B. G. Buchanan,O. Jardetzky in yeast are highly conserved in eukaryotes including humans. Mutations in factors involved in rRNA modification are linked to several rare severe human diseases (e.g., X-linked Dyskeratosis congenita, the Bowen–Conradi syndrome and the William–Beuren disease). In this chapter, we summarize all rRN作者: 違抗 時(shí)間: 2025-3-22 13:17
I. C. P. Smith we describe a set of plasmids that can be used as template for PCR-based MNase tagging of genes by homologous recombination in .. The templates enable both N- and C-terminal tagging with MNase in combination with linker regions of different lengths and properties. In addition, an affinity tag is in作者: Accord 時(shí)間: 2025-3-22 21:06 作者: CROAK 時(shí)間: 2025-3-22 23:47
J. D. Glickson,J. P. Wehrle,S. S. Rajan,S. J. Li,R. G. Steenformat, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..?.Invaluable and easy to use, .Ribosome Display and Related Technologies作者: ATOPY 時(shí)間: 2025-3-23 03:07 作者: carotenoids 時(shí)間: 2025-3-23 08:49 作者: Allure 時(shí)間: 2025-3-23 09:47 作者: 大包裹 時(shí)間: 2025-3-23 14:24
NMR Imaging of the Human Brain-Insights into Neurological Diseases,ntext. In other words, we are still using the same parameters for diagnosis as we have in CT for years. The location of the lesion, its margins, change in blood-brain-barrier as denoted by an intravenously administered contrast agent, and evolution over time are all weighed in the context of the cli作者: notion 時(shí)間: 2025-3-23 19:06
Book 1990 1952, studies of liquids and solids with broad resonance lines dominated the field of NMR. However, the reports of 3 1 P NMR chemical shifts in several corrpounds in 1949 by Khight, of 14 N resonances in several ions by Proctor and Yu in 1950, and of 1 9 F resonances in several corrpounds in 1950 b作者: anarchist 時(shí)間: 2025-3-24 01:54 作者: 構(gòu)想 時(shí)間: 2025-3-24 05:06
NMR: Principles and Applications to Biomedical Research作者: Etching 時(shí)間: 2025-3-24 07:26 作者: guardianship 時(shí)間: 2025-3-24 11:35
A. A. Bothner-Bymplexity of rRNAs, and Part Six provides readers with a review of eukaryotic translation and - for the first time - describes a new method to analyze translation in vitro. Written in the highly successful .Meth978-1-0716-2503-3978-1-0716-2501-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: EWER 時(shí)間: 2025-3-24 15:43 作者: 古代 時(shí)間: 2025-3-24 19:45 作者: 不透明 時(shí)間: 2025-3-25 01:24 作者: Antigen 時(shí)間: 2025-3-25 07:23 作者: 討好女人 時(shí)間: 2025-3-25 08:24
S. Adlermaterials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..?.Invaluable and easy to use, .Ribosome Display and Related Technologies978-1-4939-5872-6978-1-61779-379-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Odyssey 時(shí)間: 2025-3-25 12:04 作者: 猜忌 時(shí)間: 2025-3-25 17:28
J. C. Gorematerials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..?.Invaluable and easy to use, .Ribosome Display and Related Technologies978-1-4939-5872-6978-1-61779-379-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: ORBIT 時(shí)間: 2025-3-25 21:42
G. L. Wolfmaterials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..?.Invaluable and easy to use, .Ribosome Display and Related Technologies978-1-4939-5872-6978-1-61779-379-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: dysphagia 時(shí)間: 2025-3-26 00:15 作者: 使人煩燥 時(shí)間: 2025-3-26 04:26
978-1-4612-7957-0Springer-Verlag New York Inc. 1990作者: hypnotic 時(shí)間: 2025-3-26 10:33 作者: 供過(guò)于求 時(shí)間: 2025-3-26 12:40
https://doi.org/10.1007/978-1-4612-3300-8Optische Koh?renztomografie; imaging; liquid water; magnetic resonance; protein; spectroscopy; transport作者: faculty 時(shí)間: 2025-3-26 18:21 作者: Ingenuity 時(shí)間: 2025-3-26 21:09
Two-Dimensional Fourier Transform NMR: Homonuclear and Heteronuclear Couplings-Multiple Quantum Filion of a single variable, the frequency at which the signal would be observed in a steady state experiment. As clearly described by Dr. Farrar, the spectrum is obtained by Fourier transformation of the signal measured as a function of the single variable time, following application of a short r.f. pulse (Ernst et al 1966).作者: 跳脫衣舞的人 時(shí)間: 2025-3-27 04:41 作者: JECT 時(shí)間: 2025-3-27 09:02 作者: recession 時(shí)間: 2025-3-27 12:02 作者: 鋼盔 時(shí)間: 2025-3-27 17:02
Introduction to NMR Imaging, the many techniques that have been developed until now, it has proven to be the roost versatile and free of instrumental artifacts. In this article, I will try to explain how the SW technique works and some recent innovations based on it.作者: 冒煙 時(shí)間: 2025-3-27 18:57
Principles of Pulse NMR Spectroscopy,dramatic and exciting new ways of applying the power and versatility of NMR methods, a wide range of other applications also exit. In this introductory chapter we outline the basic principles of NMR spectroscopy and mention a few of the more important applications (Farrar 1987).作者: Contend 時(shí)間: 2025-3-27 22:36
Application of Solid State NMR to the Lipids of Model and Biological Membranes,pids can lead to quite different properties. It has thus become essential to develop methods to study the properties of these lipids, especially in the natural biological environment of the untouched membrane. Nuclear magnetic resonance has had a strong role to play in this development.作者: JADED 時(shí)間: 2025-3-28 04:23 作者: 防御 時(shí)間: 2025-3-28 06:29
1H-NMR Spectroscopy of Brain,ies with .H-NMR have been made possible in living organisms by the development of pulse sequences that suppress the large proton signal from water and allow detection of protons contained in compounds present at lower concentrations.作者: 露天歷史劇 時(shí)間: 2025-3-28 12:18 作者: Decibel 時(shí)間: 2025-3-28 15:09
Solid State 31P and 27Al NMR Studies of Model Membranes and Mammalian Brain: Possible Implications insoluble, and concentrations of dissolved aluminum are, therefore, low in both surface and subsoil water. The solubility of aluminum increases at lower pH values in the presence of calcium which has a buffering effect that facilitates aluminum dissolution (Ganrot 1986).作者: 單片眼鏡 時(shí)間: 2025-3-28 20:06 作者: Self-Help-Group 時(shí)間: 2025-3-29 02:28
High-Resolution NMR of Solids,ation mechanisms rather than as line broadening effects (Lyerla et al 1974). The most important of these are chemical shift anisotropy, dipolar coupling, conformation effects, and quadrupole splittings.作者: 越自我 時(shí)間: 2025-3-29 03:28
NMR Imaging: Techniques and Developments,y Bothner-By) or spin warp technique (see chapter by Lowe), are presented elsewhere in this volume. Here we emphasize that NMR images of several different types can be produced, and the practical roles of some of these have not yet been clearly defined.作者: 交響樂(lè) 時(shí)間: 2025-3-29 11:11 作者: Apoptosis 時(shí)間: 2025-3-29 13:34 作者: 帳單 時(shí)間: 2025-3-29 16:34
Nuclear Magnetic Resonance and Cell pH with a Focus on Brain pH,rather than a truly homogeneous solution and local microscopic pH environments probably exist. Nevertheless, “overall” or “mean” or “average” cytoplasmic pH is an important quantity which helps define the cell’s metabolic state.作者: dominant 時(shí)間: 2025-3-29 22:12
er to appreciate the elegance and power of this technology a historical perspective is in order. In 1924 Pauli suggested that hydrogen nuclei might possess a magnetic IIlOlllent. This was in fact confinned by Rabbi in 1939 who demonstrated that a beam of hydrogen molecules in the presence of a magne作者: 軟弱 時(shí)間: 2025-3-30 00:09
Principles of Pulse NMR Spectroscopy,hem in a magnetic field they will develop a net magnetization. NMR spectroscopy is concerned primarily with compounds of this type. The human body is composed primarily of diamagnetic materials and because of this whole body imaging is possible. Although whole body and other imaging experiments are 作者: 死亡 時(shí)間: 2025-3-30 08:08
Relaxation Theory with Applications to Biological Studies,hydrogen (.H) NMR imaging for several reasons. Their values affect the selection of pulse sequence parameters in imaging. The differences among the NMR relaxation times of the various tissues and of pathological states of these tissues are crucial to the use of NMR imaging in the detection of anatom作者: garrulous 時(shí)間: 2025-3-30 08:26 作者: Preamble 時(shí)間: 2025-3-30 15:51
High-Resolution NMR of Solids,la et al 1981). Rapid tumbling in the liquid state averages orientation dependence, so these interactions appear (when they appear at all) as T. relaxation mechanisms rather than as line broadening effects (Lyerla et al 1974). The most important of these are chemical shift anisotropy, dipolar coupli作者: 門(mén)閂 時(shí)間: 2025-3-30 17:02 作者: 溺愛(ài) 時(shí)間: 2025-3-30 22:21
Application of Solid State NMR to the Lipids of Model and Biological Membranes,lipids were there to stabilize them or to force them into the relevant conformations, as well as to provide a passive hydrophobic barrier. Views have changed! It is now known that lipids play an important role in the immunological and transport properties of membranes, and that different mixes of li作者: HILAR 時(shí)間: 2025-3-31 03:08 作者: 扔掉掐死你 時(shí)間: 2025-3-31 07:46
,31P NMR of Brain Aging and Alzheimer’s Disease,extra-neural tissue (Barany and Glonek, 1984). Neural tissue studies have been performed on tissue extracts (Pettegrew et al 1979, 1986, 1987, 1988a, Glonek et al 1982), . brain slices (Cohen et al 1984), and on animals and humans . (Chance et al 1978, Ackerman et al 1980, Cady et al 1983, Petroff e作者: Adenoma 時(shí)間: 2025-3-31 10:35
NMR Spectroscopy of Tumors,n differences in relaxation times, which are usually longer for tumors, and distortion of surrounding anatomy. While imaging has proven very sensitive, particularly for central nervous system tumors, it has limited specificity, making discrimination of tumors from a number of nonmalignant pathologie作者: 破譯密碼 時(shí)間: 2025-3-31 17:14 作者: 自作多情 時(shí)間: 2025-3-31 20:31
23Na and 7Li NMR Studies of Mammalian Cells: Assessment of Cation Transport and Cytoskeletal Struct processes serve to alter the chemical state of the ion and the position of carefully controlled equilibria. Alterations in Na. transmembrane unidirectional rate constants with resultant alterations in intracellular Na. concentration have been implicated in a number of human disease processes such a作者: NAUT 時(shí)間: 2025-4-1 00:03 作者: UNT 時(shí)間: 2025-4-1 03:07
31P in vivo Spectroscopy of Adult Human Brain,ble tool in the fields of chemistry and physics. Only within the past few years has NMR been directly applied to the field of medicine. One application has resulted in the development of anatomical imaging (MRI); the impact of which has been compared to the development of the x-ray.作者: Hamper 時(shí)間: 2025-4-1 07:51
1H-NMR Spectroscopy of Brain,2). The usefulness of .H-NMR for . studies has been shown in hypoxia (Behar et al 1983), hypoglycemia (Behar et al 1985), seizures (Petroff et al 1986), and ischemia (Gadian et al 1986, Crockard et al 1987). Measurement of lactate and N-acetyl groups has been done in humans (LuYten et al 1986). Stud作者: anaerobic 時(shí)間: 2025-4-1 10:58
Nuclear Magnetic Resonance and Cell pH with a Focus on Brain pH,bolism, it is important to be able to measure cell pH accurately if the metabolic state of the cell is to be properly assessed. It is not strictly correct to discuss “cell pH” as a single entity since there are different pH regions within the cell. In addition to the pH within organelles such as the作者: 眨眼 時(shí)間: 2025-4-1 15:33
Introduction to NMR Imaging, the many techniques that have been developed until now, it has proven to be the roost versatile and free of instrumental artifacts. In this article, I will try to explain how the SW technique works and some recent innovations based on it.作者: Exposure 時(shí)間: 2025-4-1 20:17
NMR Imaging: Techniques and Developments,that can be performed to yield different sorts of information. The details of MRI involved, for example, in the two dimensional Fourier (see chapter by Bothner-By) or spin warp technique (see chapter by Lowe), are presented elsewhere in this volume. Here we emphasize that NMR images of several diffe作者: 開(kāi)始沒(méi)有 時(shí)間: 2025-4-1 22:47 作者: 使人入神 時(shí)間: 2025-4-2 02:49
