標(biāo)題: Titlebook: Microcalorimetry of Biological Molecules; Methods and Protocol Eric Ennifar Book 2019 Springer Science+Business Media, LLC, part of Springe [打印本頁] 作者: 厭倦了我 時(shí)間: 2025-3-21 17:49
書目名稱Microcalorimetry of Biological Molecules影響因子(影響力)
書目名稱Microcalorimetry of Biological Molecules影響因子(影響力)學(xué)科排名
書目名稱Microcalorimetry of Biological Molecules網(wǎng)絡(luò)公開度
書目名稱Microcalorimetry of Biological Molecules網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Microcalorimetry of Biological Molecules被引頻次
書目名稱Microcalorimetry of Biological Molecules被引頻次學(xué)科排名
書目名稱Microcalorimetry of Biological Molecules年度引用
書目名稱Microcalorimetry of Biological Molecules年度引用學(xué)科排名
書目名稱Microcalorimetry of Biological Molecules讀者反饋
書目名稱Microcalorimetry of Biological Molecules讀者反饋學(xué)科排名
作者: Cardiac-Output 時(shí)間: 2025-3-21 21:38 作者: fertilizer 時(shí)間: 2025-3-22 04:07
Philipp O. Tsvetkov,Fran?ois Devredgn courses, as well as for undergraduate-level project-based spatial science courses..Keywords:? proposal writing, grant writing, research, geography, spatial science.978-94-007-9345-3978-94-007-2281-1作者: 屈尊 時(shí)間: 2025-3-22 07:03 作者: 友好 時(shí)間: 2025-3-22 10:34 作者: locus-ceruleus 時(shí)間: 2025-3-22 16:30
Rafael Claveria-Gimeno,Sonia Vega,Olga Abian,Adrian Velazquez-Campoygn courses, as well as for undergraduate-level project-based spatial science courses..Keywords:? proposal writing, grant writing, research, geography, spatial science.978-94-007-9345-3978-94-007-2281-1作者: 獨(dú)特性 時(shí)間: 2025-3-22 20:01
Eva Mu?oz,Juan Sabíngn courses, as well as for undergraduate-level project-based spatial science courses..Keywords:? proposal writing, grant writing, research, geography, spatial science.978-94-007-9345-3978-94-007-2281-1作者: Peak-Bone-Mass 時(shí)間: 2025-3-22 22:15 作者: 剝皮 時(shí)間: 2025-3-23 03:36 作者: 修正案 時(shí)間: 2025-3-23 05:47
Emma Schenckbecher,Beno?t Meyer,Eric Ennifarposal Writing in Spatial Science" can serve as a textbook for graduate-level research-design courses, as well as for undergraduate-level project-based spatial science courses..Keywords:? proposal writing, grant writing, research, geography, spatial science.作者: CRATE 時(shí)間: 2025-3-23 11:52 作者: depreciate 時(shí)間: 2025-3-23 15:07
Ryo Amano,Tomohisa Furukawa,Taiichi Sakamotoposal Writing in Spatial Science" can serve as a textbook for graduate-level research-design courses, as well as for undergraduate-level project-based spatial science courses..Keywords:? proposal writing, grant writing, research, geography, spatial science.作者: Senescent 時(shí)間: 2025-3-23 18:12
Beno?t Meyer,Cyrielle da Veiga,Philippe Dumas,Eric Ennifarposal Writing in Spatial Science" can serve as a textbook for graduate-level research-design courses, as well as for undergraduate-level project-based spatial science courses..Keywords:? proposal writing, grant writing, research, geography, spatial science.作者: 延期 時(shí)間: 2025-3-23 22:56
Anna Solokhina,Gernot Bonkat,Olivier Braissantposal Writing in Spatial Science" can serve as a textbook for graduate-level research-design courses, as well as for undergraduate-level project-based spatial science courses..Keywords:? proposal writing, grant writing, research, geography, spatial science.作者: BULLY 時(shí)間: 2025-3-24 03:40 作者: –DOX 時(shí)間: 2025-3-24 09:04 作者: calorie 時(shí)間: 2025-3-24 13:38
Plasmatic Signature of Disease by Differential Scanning Calorimetry (DSC)elopment of standardized methods of data analysis are necessary to reach the promising diagnostic potential of this methodology. Using plasma samples from healthy individuals and glioblastoma patients, we outline the steps necessary to obtain a plasmatic calorimetric profile with VP-DSC instrument a作者: 個(gè)人長篇演說 時(shí)間: 2025-3-24 17:40 作者: Aromatic 時(shí)間: 2025-3-24 22:41
ITC Studies of Ribosome/Antibiotics Interactionsl very poor..In this chapter we describe the use of ITC microcalorimetry to investigate the binding of bacterial ribosome to two antibiotics targeting the peptide tunnel: macrolides and proline-rich antimicrobial peptides (PrAMPs). This strategy yields reliable and artifact-free binding parameters f作者: relieve 時(shí)間: 2025-3-25 00:09 作者: GNAT 時(shí)間: 2025-3-25 05:01
1064-3745 practical, .Microcalorimetry of Biological Molecules: Methods and Protocols. aims to ensure successful results in the further study of this vital field..978-1-4939-9179-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 軟弱 時(shí)間: 2025-3-25 08:26
Value of DSC in Characterization and Optimization of Protein StabilityDifferential scanning calorimetry (DSC) is a well-established technique for biomolecular stability studies. The technique is based on forced thermal denaturation of biomolecules in solution. Here we describe the use of DSC for characterization and optimization of stability of two proteins, a protein kinase and a mAb protein.作者: Multiple 時(shí)間: 2025-3-25 14:14
Analysis of Isothermal Titration Calorimetry Data for Complex Interactions Using I2CITC for systems involving a self-aggregating ligand and a host offering one or two binding sites can be analyzed, how interaction models can be tested, and how confidence intervals for the optimized parameters can be determined.作者: Opponent 時(shí)間: 2025-3-25 19:07 作者: encomiast 時(shí)間: 2025-3-25 20:40
Microcalorimetry of Biological Molecules978-1-4939-9179-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: GOAT 時(shí)間: 2025-3-26 01:49
Methods in Molecular Biologyhttp://image.papertrans.cn/m/image/633126.jpg作者: 細(xì)微差別 時(shí)間: 2025-3-26 04:57
https://doi.org/10.1007/978-1-4939-9179-2thermodynamic parameters; structure-based drug design; enzyme kinetics; conformational changes; isotherm作者: 不幸的人 時(shí)間: 2025-3-26 11:28
Eric EnnifarIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains keynotes and implementation advice from the experts作者: Hypomania 時(shí)間: 2025-3-26 14:29
Protocols of IATC, DSC, and PPC: The Multistate Structural Transition of Cytochrome aled that the MG state is an equilibrium intermediate state of the reversible thermal three-state transition of the protein, and we successfully determined its volumetric properties by pressure perturbation calorimetry (PPC). Our findings underscore the importance of a precise calorimetry and analysis model for protein research.作者: insurrection 時(shí)間: 2025-3-26 18:04 作者: MOTTO 時(shí)間: 2025-3-26 21:14
Characterization of Microtubule-Associated Proteins (MAPs) and Tubulin Interactions by Isothermal Tiodynamic method that enables a full thermodynamic characterization of the interaction after a single titration experiment. We provide here the protocols to apply ITC to tubulin interaction with either stathmin or tau, which will help to avoid the common pitfalls in this very powerful and sensitive method.作者: BILIO 時(shí)間: 2025-3-27 01:42 作者: Climate 時(shí)間: 2025-3-27 07:51 作者: 實(shí)施生效 時(shí)間: 2025-3-27 11:31
High-Quality Data of Protein/Peptide Interaction by Isothermal Titration Calorimetryr the protein, making the sample quality and data acquisition all the more critical. This chapter emphasizes more specifically the relevance of those points to improve the reproducibility of ITC measurements and to gain high-quality thermodynamic parameters.作者: Arctic 時(shí)間: 2025-3-27 16:45 作者: 合唱隊(duì) 時(shí)間: 2025-3-27 20:03
Tinkering with Binding Polynomials in Isothermal Titration Calorimetryr handling the complexities that can be encountered when studying macromolecule-ligand interactions, though it has been deemed troublesome. The goal of this chapter is to provide a quite simple and widely available set of training experiments aimed at mastering the formalism of the binding polynomial applied to isothermal titration calorimetry.作者: 新奇 時(shí)間: 2025-3-28 00:54 作者: 諷刺滑稽戲劇 時(shí)間: 2025-3-28 02:31
Isothermal Titration Calorimetry Measurements of Riboswitch-Ligand Interactionsl or translational output. For over a decade, isothermal titration calorimetry (ITC) has been used to investigate how riboswitches interact with small molecules. We present methods for assaying RNA-ligand interactions using ITC and analyzing resulting data to estimate thermodynamic parameters associated with binding.作者: adumbrate 時(shí)間: 2025-3-28 07:39 作者: GRIPE 時(shí)間: 2025-3-28 13:01 作者: NEEDY 時(shí)間: 2025-3-28 17:02 作者: 違抗 時(shí)間: 2025-3-28 20:03
The Contribution of Differential Scanning Calorimetry for the Study of Peptide/Lipid Interactionsicated in several pathologies. They constitute important targets because they are either at the basis of novel therapies (drug delivery for CPPs or antimicrobial activity for AMPs) or they are the agents causing these pathologies (viral and amyloid peptides). They all share the common property of in作者: 擁護(hù) 時(shí)間: 2025-3-29 03:00
Protocols of IATC, DSC, and PPC: The Multistate Structural Transition of Cytochrome terize the thermodynamic property changes accompanying three-dimensional structure changes. We developed isothermal acid-titration calorimetry (IATC) to evaluate the pH dependence of protein enthalpy. Using the double deconvolution method with precise differential scanning calorimetry (DSC), we reve作者: 使激動 時(shí)間: 2025-3-29 04:13
Plasmatic Signature of Disease by Differential Scanning Calorimetry (DSC). It allows to determine the denaturation temperature and enthalpy of individual domains of proteins, thus giving new insights into their domain organization and ligand interaction. Over the past decade, it has been shown that this technique can also be used to study biofluids such as plasma or cere作者: 非實(shí)體 時(shí)間: 2025-3-29 10:18
Intrinsic Thermodynamics of Protein-Ligand Binding by Isothermal Titration Calorimetry as Aid to Drun. This technique is commonly used in drug development programs when low-molecular-weight molecules are sought that bind tightly and specifically to a protein (disease target) molecule. The method allows a complete thermodynamic characterization of an interaction, i.e., ITC enables direct determinat作者: 暫時(shí)中止 時(shí)間: 2025-3-29 12:43 作者: 窗簾等 時(shí)間: 2025-3-29 16:46 作者: 狂怒 時(shí)間: 2025-3-29 19:50
High-Quality Data of Protein/Peptide Interaction by Isothermal Titration Calorimetrys of affinities and thermodynamic parameters of single interactions in order to fully dissect the mechanisms of binding. To this end, isothermal titration calorimetry (ITC) is a well-established and convenient label-free technique covering a broad range of affinities..This review describes the caref作者: 試驗(yàn) 時(shí)間: 2025-3-30 03:38
ITC Measurement for High-Affinity Aptamers Binding to Their Target Proteinsmatic evolution of ligands by exponential enrichment (SELEX). Because of their high affinity and specificity, aptamers were developed as therapeutic agents. Although aptamers are investigated as promising therapeutic agents, the mechanism of their high affinity and specificity is not clear. Therefor作者: 擴(kuò)張 時(shí)間: 2025-3-30 04:43
Thermodynamics of Molecular Machines Using Incremental ITChly regulated tasks, with a remarkable accuracy. Significant advances in structural studies during the past 20?years provided a wealth of information regarding their architecture and considerably contributed to a better understanding of their mechanism of action. However, the three-dimensional struc作者: ensemble 時(shí)間: 2025-3-30 11:08
Measuring the Metabolic Activity of Mature Mycobacterial Biofilms Using Isothermal Microcalorimetryoping new antibiofilm compounds and potentially new treatments. Current culture-based and microscopic methods although of much use have several drawbacks. Isothermal calorimetry can be useful in this context by allowing measurements of the metabolic activity of biofilm grown and maintained on solid 作者: 浪費(fèi)物質(zhì) 時(shí)間: 2025-3-30 13:52 作者: Infelicity 時(shí)間: 2025-3-30 16:52 作者: Digest 時(shí)間: 2025-3-30 22:35 作者: 發(fā)芽 時(shí)間: 2025-3-31 01:44 作者: Rebate 時(shí)間: 2025-3-31 06:52 作者: Ancestor 時(shí)間: 2025-3-31 09:57 作者: Visual-Acuity 時(shí)間: 2025-3-31 14:04
Shigeyoshi Nakamura,Shun-ichi Kidokorod practical complications when ‘doing research’. Graduate students in a broad range of related fields need to learn how to tackle the discipline-specific issues of space, place, and scale as they propose and perform research in the spatial sciences. This practical textbook and overview blends plenty作者: 帶子 時(shí)間: 2025-3-31 19:34
Katherine Bowers,Natalia Markova what can be improved and so on.Update and expanded graphics.The complex interactions between human and physical systems confronting social scientists and policymakers pose unique conceptual, methodological, and practical complications when ‘doing research’. Graduate students in a broad range of rel作者: 修改 時(shí)間: 2025-4-1 01:05
