標題: Titlebook: Metronomic Chemotherapy; Pharmacology and Cli Guido Bocci,Giulio Francia Book 2014 The Editor(s) (if applicable) and The Author(s), under e [打印本頁] 作者: 側面上下 時間: 2025-3-21 18:51
書目名稱Metronomic Chemotherapy影響因子(影響力)
書目名稱Metronomic Chemotherapy影響因子(影響力)學科排名
書目名稱Metronomic Chemotherapy網(wǎng)絡公開度
書目名稱Metronomic Chemotherapy網(wǎng)絡公開度學科排名
書目名稱Metronomic Chemotherapy被引頻次
書目名稱Metronomic Chemotherapy被引頻次學科排名
書目名稱Metronomic Chemotherapy年度引用
書目名稱Metronomic Chemotherapy年度引用學科排名
書目名稱Metronomic Chemotherapy讀者反饋
書目名稱Metronomic Chemotherapy讀者反饋學科排名
作者: 咆哮 時間: 2025-3-22 00:17
Book 2014preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemot作者: STENT 時間: 2025-3-22 04:20
Development and Evolution of the Concept of Metronomic Chemotherapy: A Personal Perspectiveetronomic chemotherapy concept is summarized along with suggestions for improving its impact as a promising means of achieving better and less toxic cancer control, not only in patients in low and middle income countries, but also patients in highly developed high income countries as well.作者: 截斷 時間: 2025-3-22 06:21 作者: Fatten 時間: 2025-3-22 09:15
Clinical Activity of Metronomic Chemotherapy in Central Nervous System Cancersma models and numerous clinical applications of metronomic regimens (e.g. etoposide, temozolomide) for adult patients with tumors of CNS have been described. Moreover, metronomic treatment may serve as a useful platform for combination strategies in certain CNS tumors.作者: NIL 時間: 2025-3-22 16:04 作者: Exploit 時間: 2025-3-22 20:59
Metronomic Chemotherapy in Pediatric Malignanciesatriccancer. Maintenancelowdosechemotherapyhasproven itsbenefits in increasingoverallsurvival inseveral pediatric cancer. Thischapter isreviewingthecurrentknowledge ofpediatric metronomic chemotherapy and potential forfuture development ascytotoxic agents or in combinationwith targetedtherapy including its potentialapplicationinemergingcountries.作者: exercise 時間: 2025-3-22 22:13 作者: fibula 時間: 2025-3-23 02:13
Preclinical Activity of Metronomic Regimens with Alkylating Agents and Antimetabolitesnomic chemotherapy approach. Much of this report concerns cyclophosphamide, since, in this context, it is the most widely explored drug so far. The report also draws attention to the numerous cancer cell lines and the main murine models used.作者: Limousine 時間: 2025-3-23 08:16 作者: 噱頭 時間: 2025-3-23 10:11
Mechanisms of Action of Low-Dose Metronomic Chemotherapygs in low doses. This relatively new treatment strategy concept is called low-dose metronomic (LDM) chemotherapy. The therapeutic efficacy of LDM has been assessed for reducing the tumor load during the acute phase and in delaying relapse during the maintenance phase. The major benefits found in usi作者: 腐蝕 時間: 2025-3-23 15:37
Effects of Metronomic Chemotherapy on Immunityincluding immune cells. Therefore, conventional and maximum-tolerated dose chemotherapy is inevitably associated with the risk of immunity deterioration. Metronomic chemotherapy is a unique protocol that administers chemotherapeutic agents at relatively low doses, without prolonged drug-free periods作者: Morphine 時間: 2025-3-23 20:42 作者: 蛤肉 時間: 2025-3-24 02:07
Metronomic Chemotherapy Regimens Using Microtubule-Targeting Agents: Mechanisms of Action, Preclinicers. Although originally administered at or close to the maximum tolerated dose once every 3 weeks, the discovery of their potent antiangiogenic properties at the end of the 1990s has led to the re-evaluation of treatment protocols. Nowadays, MTAs are often administered at lower doses either weekly 作者: Cpap155 時間: 2025-3-24 05:41
Metronomic Chemotherapy in Breast Cancersme metastatic during the follow-up period and need a personalized and/or target treatment approach. Metronomic chemotherapy can be regarded as a multi-targeted therapy for advanced disease, combining effects not only on tumor cells but also on their microenvironment by inhibiting tumor angiogenesis,作者: 木質 時間: 2025-3-24 06:46 作者: helper-T-cells 時間: 2025-3-24 13:56
Clinical Trials of Low-Dose Metronomic Chemotherapy in Castration-Resistant Prostate Cancerte cyclic treatment interruptions. Recently, LDM chemotherapy has gained traction for the treatment of castration-resistant prostate cancer (CRPC). Its excellent safety profile and relatively low rate of severe (i.e., grade 3/4) toxicities make it an enviable treatment, especially for elderly and fr作者: 使饑餓 時間: 2025-3-24 15:59 作者: STRIA 時間: 2025-3-24 20:12
Clinical Activity of Metronomic Chemotherapy in Central Nervous System Cancerscharacteristics in malignant gliomas is the robust and aberrant vasculature within the tumor which could be the target for the frequent administration of low-dose metronomic chemotherapy. This chapter will mainly focus on determining current status and recent trends of metronomic treatment for CNS t作者: GROUP 時間: 2025-3-25 02:34
Metronomic Chemotherapy in Pediatric Malignanciesconventional chemotherapy.Several pediatric preclinical solid tumor modelsaresupportingthe clinical development of this newtherapeuticmodality in pediatriccancer. Maintenancelowdosechemotherapyhasproven itsbenefits in increasingoverallsurvival inseveral pediatric cancer. Thischapter isreviewingthecu作者: 攀登 時間: 2025-3-25 04:30 作者: novelty 時間: 2025-3-25 09:10 作者: 瑣碎 時間: 2025-3-25 12:39 作者: harbinger 時間: 2025-3-25 16:03 作者: 改變立場 時間: 2025-3-25 22:07
Pharmacokinetics and Pharmacogenetics of Metronomic Chemotherapyd pharmacogenetics data on this dosing regimen are available. Indeed, only the pharmacokinetics of metronomically administered drugs, such as irinotecan, UFT, and vinorelbine, have been described in patients, but no data are available on the most widely explored agents in such an approach like cyclo作者: anniversary 時間: 2025-3-26 00:51
und ?konomische Entwicklungen sowie auf deren Deutung und politische Bearbeitung durch die parlamentarischen Demokratien. Zugleich geriet er aber, insbesondere in Deutschland nach Gründung der Bundesrepublik, sofort unter gesellschaftlichen und staatlichen Druck, weil ein Wiederaufleben von NS-Geda作者: Nebulizer 時間: 2025-3-26 04:47 作者: 細微差別 時間: 2025-3-26 12:20
Robert S. Kerbel PhDtaat auf eine Fundamentalkritik, die seinen Nutzen für die Volkswirtschaft bestreitet, massenhaften Leistungsmi?brauch wittert und statt der ?ffentlichen ?Rundumversorgung“ für mehr private Eigenvorsorge pl?diert. Durch die Vereinigung beider deutscher Staaten ergaben sich für einen liberalkonservat作者: 蹣跚 時間: 2025-3-26 13:49
Ella Fremder,Yuval Shaked PhDroblemen auf die Tagesordnung gesetzt. Dazu geh?ren nicht nur die rechtliche Stellung von Ausl?ndern in Deutschland, nicht nur ihre benachteiligte Position auf den Arbeits-, Wohnungs- und Bildungsm?rkten, sondern auch jene prek?ren kommunikativen Schnittstellen, an denen sich Bilder des jeweils ande作者: 思考才皺眉 時間: 2025-3-26 18:51
Mamoru Harada MD, PhDtaat auf eine Fundamentalkritik, die seinen Nutzen für die Volkswirtschaft bestreitet, massenhaften Leistungsmi?brauch wittert und statt der ?ffentlichen ?Rundumversorgung“ für mehr private Eigenvorsorge pl?diert. Durch die Vereinigung beider deutscher Staaten ergaben sich für einen liberalkonservat作者: 不愿 時間: 2025-3-26 22:48 作者: 青石板 時間: 2025-3-27 02:13
Lisa Salvatore,Federica Zoratto,Fotios Loupakis,Alfredo Falconerliegende Beitrag untersucht die Validit?t der darauf aufbauenden Messinstrumente am Beispiel des T.-M.s. Mithilfe dieser einzigartigen L?ngsschnittstudie werden für einen Zeitraum von zwei Jahrzehnten die interne Struktur und Entwicklung der Messung und des Ph?nomens ?Rechtsextremismus‘ analysiert.作者: Cumulus 時間: 2025-3-27 09:14 作者: 連鎖 時間: 2025-3-27 13:11
https://doi.org/10.1007/978-3-662-43604-2Antiangiogenic drugs; Cancer; Metronomic chemotherapy; Pharmacology作者: 過多 時間: 2025-3-27 16:25
Guido Bocci,Giulio FranciaCovers all aspects of metronomic chemotherapy.Describes the pharmacological bases of metronomic chemotherapy.Presents and discusses the clinical results of all published studies on metronomic chemothe作者: Hdl348 時間: 2025-3-27 18:14 作者: 耕種 時間: 2025-3-27 22:36 作者: 變白 時間: 2025-3-28 03:43
The Role of Metronomic Chemotherapy in the Treatment of Metastatic Colorectal Cancer Patients or partial antiangiogenic activity such as bevacizumab, aflibercept, and regorafenib. Metronomic chemotherapy may be an alternative strategy for targeting tumor angiogenesis and several clinical studies suggested its promising activity and its extremely favorable toxicity profile in the treatment of metastatic colorectal cancer patients.作者: 拖債 時間: 2025-3-28 07:17
Mechanisms of Action of Low-Dose Metronomic Chemotherapyction. Initially, LDM was considered an antiangiogenic treatment strategy; however, in the last decade additional preclinical studies uncovered other possible mechanisms including enhancing the antitumor immune response, substantially increasing the efficacy of targeted drugs by various mechanisms, 作者: aspersion 時間: 2025-3-28 13:28
Effects of Metronomic Chemotherapy on Immunity-bearing hosts. However, administration protocols heavily influence the host’s immunity because chemotherapeutic agents potentially kill proliferating lymphocytes. To this end, we investigated the effects of a CTX administration protocol on the in vivo induction of antitumor T cells in a preclinical作者: 妨礙 時間: 2025-3-28 15:40
Metronomic Chemotherapy Regimens Using Microtubule-Targeting Agents: Mechanisms of Action, PreclinicMTAs. We also present their effects on the immune system, which may contribute to the antitumour efficacy of MTA-based metronomic chemotherapy. Then, we review the results obtained with this type of therapeutic approach in preclinical models of human cancer, focusing on the most promising combinatio作者: filicide 時間: 2025-3-28 19:25
Metronomic Chemotherapy in Breast Cancersg for new applications of this therapeutic strategy. Biomarkers are being developed to identify reliable surrogate markers of response and also to identify the proper patients to be treated. Nowadays, there are several ongoing trials to identify the optimal regimen and schedule of metronomic chemoth作者: exostosis 時間: 2025-3-28 22:57
Clinical Trials of Low-Dose Metronomic Chemotherapy in Castration-Resistant Prostate Cancerotherapy was found to be beneficial in almost 60 % of patients (mean clinical benefit rate of 58.08?±?20.30). Severe treatment-associated side effects were rarely seen, with anemia being the most commonly reported. One comparative single-center study showed a superior safety profile and comparable b作者: 無法取消 時間: 2025-3-29 03:04
Metronomic Chemotherapy in Hematological Malignanciesn encouraging efficacy with metronomic chemotherapy in these disease categories, with generally low toxicity and cost. With the growing availability of the target-specific biological agents, some of which are specific for antiangiogenesis, it is conceivable that metronomic chemotherapy, either alone作者: Hla461 時間: 2025-3-29 08:43 作者: PACK 時間: 2025-3-29 11:43
Metronomic Chemotherapy in Non-Small-Cell Lung Cancersystem function through the elimination of immune suppressive cells. Numerous studies have investigated the efficacy of metronomic strategy in NSCLC patients with very promising results. Several chemotherapeutic agents, such as vinorelbine, gemcitabine, cyclophosphamide, and docetaxel, have been tes作者: incisive 時間: 2025-3-29 18:03
Pharmacokinetics and Pharmacogenetics of Metronomic Chemotherapy in various tumors, it remains largely unknown which genetic backgrounds could affect or predict the clinical response of patients. Trials integrating pharmacokinetic and pharmacogenetics research are necessary to better evaluate the clinical benefit of metronomic chemotherapy.作者: 債務 時間: 2025-3-29 20:01 作者: myriad 時間: 2025-3-30 00:14
angerufen und ihr Verhalten insgesamt entscheidet wesentlich darüber, ob integrative oder desintegrative Tendenzen der multikulturellen Gesellschaft die Oberhand gewinnen werden. Natürlich ist zu berücksichtigen, da? die Zahl der nichtdeutschen Tatverd?chtigen st?ndig steigt und Polizeibeamte von da作者: Epidural-Space 時間: 2025-3-30 04:38 作者: 不怕任性 時間: 2025-3-30 10:04
Ella Fremder,Yuval Shaked PhDangerufen und ihr Verhalten insgesamt entscheidet wesentlich darüber, ob integrative oder desintegrative Tendenzen der multikulturellen Gesellschaft die Oberhand gewinnen werden. Natürlich ist zu berücksichtigen, da? die Zahl der nichtdeutschen Tatverd?chtigen st?ndig steigt und Polizeibeamte von da作者: FLOAT 時間: 2025-3-30 15:11 作者: curriculum 時間: 2025-3-30 17:04 作者: 擺動 時間: 2025-3-30 21:59
Lisa Salvatore,Federica Zoratto,Fotios Loupakis,Alfredo Falconeeildimensionen identifiziert werden. Durch diese Differenzierungen erfasst das Messinstrument zuverl?ssig sowohl ideologische Wandlungen des ?Rechtsextremismus‘ als auch die langfristige Entwicklung seiner Verbreitung, deren Trends auf wirtschaftliche und politische Kontextfaktoren zurückgeführt wer作者: 平躺 時間: 2025-3-31 04:44
Doo-Sik Kong MD, PhD,Do-Hyun Nam MD, PhDeildimensionen identifiziert werden. Durch diese Differenzierungen erfasst das Messinstrument zuverl?ssig sowohl ideologische Wandlungen des ?Rechtsextremismus‘ als auch die langfristige Entwicklung seiner Verbreitung, deren Trends auf wirtschaftliche und politische Kontextfaktoren zurückgeführt wer作者: exquisite 時間: 2025-3-31 06:04 作者: groggy 時間: 2025-3-31 12:47 作者: CARK 時間: 2025-3-31 17:08
Athanasios Kotsakis,Nikolaos Kentepozidis,Vassilis Georgoulias MD, PhD作者: obscurity 時間: 2025-3-31 19:32
